This book constitutes the refereed proceedings of the 4th International Workshop on Data Integration in the Life Sciences, DILS 2007, held in Philadelphia, PA, USA in July 2007. It covers new architectures and experience on using systems, managing and designing scientific workflows, mapping and matching techniques, modeling of life science data, and annotation in data integration.

This book constitutes the refereed proceedings of the Second International Workshop on Data Integration in the Life Sciences, DILS 2005, held in San Diego, CA, USA in July 2005. The 20 revised full papers presented together with 8 revised posters and demonstration papers, 2 keynote articles and 5 invited position statements were carefully reviewed and selected from 50 initial submissions. The papers are organized in topical sections on user applications, ontologies, data integration, and others and address all current issues in data integration from the life science point of view.

The development and increasingly widespread deployment of high-throughput experimental methods in the life sciences is giving rise to numerous large, c- plex and valuable data resources. This foundation of experimental data und- pins the systematic study of organismsand diseases, which increasinglydepends on the development of models of biological systems. The development of these models often requires integration of diverse experimental data resources; once constructed, the models themselves become data and present new integration challenges for tasks such as interpretation, validation and comparison. The Data Integration in the Life Sciences (DILS) Conference series brings together data and knowledge management researchers from the computer s- ence research community with bioinformaticians and computational biologists, to improve the understanding of how emerging data integration techniques can address requirements identi?ed in the life sciences. DILS 2010 was the seventh event in the series and was held in Goth- burg, Sweden during August 25–27, 2010. The associated proceedings contain 14 peer-reviewed papers and 2 invited papers. The sessions addressed ontology engineering, and in particular, evolution, matching and debugging of ontologies, akeycomponentforsemanticintegration;Web servicesasanimportanttechn- ogy for data integration in the life sciences; data and text mining techniques for discovering and recognizing biomedical entities and relationships between these entities; and information management, introducing data integration solutions for di?erent types of applications related to cancer, systems biology and - croarray experimental data, and an approach for integrating ranked data in the life sciences.

This book constitutes the refereed proceedings of the Third International Workshop on Data Integration in the Life Sciences, DILS 2006, held in Hinxton, UK in July 2006. Presents 19 revised full papers and 4 revised short papers together with 2 keynote talks, addressing current issues in data integration from the life science point of view. The papers are organized in topical sections on data integration, text mining, systems, and workflow.

This book constitutes the refereed proceedings of the First International Workshop on Data Integration in the Life Sciences, DILS 2004, held in Leipzig, Germany, in March 2004. The 13 revised full papers and 2 revised short papers presented were carefully reviewed and selected from many submissions. The papers are organized in topical sections on scientific and clinical workflows, ontologies and taxonomies, indexing and clustering, integration tools and systems, and integration techniques.

This book constitutes the refereed proceedings of the 10th International Conference on Data Integration in the Life Sciences, DILS 2014, held in Lisbon, Portugal, in July 2014. The 9 revised full papers and the 5 short papers included in this volume were carefully reviewed and selected from 20 submissions. The papers cover a range of important topics such as data integration platforms and applications; biodiversity data management; ontologies and visualization; linked data and query processing.

For several years now, there has been an exponential growth of the amount of life science data (e. g. , sequenced complete genomes, 3D structures, DNA chips, mass spectroscopy data), most of which are generated by high-throughput - periments. This exponentialcorpusof data is storedand made availablethrough a large number of databases and resources over the Web, but unfortunately still with a high degreeof semantic heterogeneity and varying levels of quality. These data must be combined together and processed by bioinformatics tools deployed on powerful and e?cient platforms to permit the uncovering of patterns, s- ilarities and in general to help in the process of discovery. Analyzing complex, voluminous, and heterogeneous data and guiding the analysis of data are thus of paramount importance and necessitate the involvement of data integration techniques. DILS 2008 was the ?fth in a workshop series that aims at fostering disc- sion, exchange, and innovation in research and development in the area of data integration for the life sciences. Each previous DILS workshop attracted around 100 researchers from all over the world and saw an increase of submitted - pers over the preceding one. This year was not an exception and the number of submitted papers increased to 54. The ProgramCommittee selected 18 of them. The selected papers cover a wide spectrum of theoretical and practical issues including data annotation, Semantic Web for the life sciences, and data mining on integrated biological data.

This book constitutes the refereed proceedings of the 8th International Conference on Data Integration in the Life Sciences, DILS 2012, held in College Park, MD, USA, on June 28-29, 2012. The 11 revised papers included in this volume were carefully reviewed and selected. The papers cover the following topics: foundations of data integration, new paradigms for data integration, and integrating clinical data.

Data integration in the life sciences continues to be important but challe- ing. The ongoing development of new experimental methods gives rise to an increasingly wide range of data sets, which in turn must be combined to allow more integrative views of biological systems. Indeed, the growing prominence of systems biology, where mathematical models characterize behaviors observed in experiments of di?erent types, emphasizes the importance of data integration to the life sciences. In this context, the representation of models of biological behavior as data in turn gives rise to challenges relating to provenance, data quality, annotation, etc., all of which are associated with signi?cant research activities within computer science. The Data Integration in the Life Sciences (DILS) Workshop Series brings together data and knowledge management researchers from the computer s- ence research community with bioinformaticians and computational biologists, to improve the understanding of how emerging data integration techniques can address requirements identi?ed in the life sciences.

This book constitutes revised selected papers from the 13th International Conference on Data Integration in the Life Sciences, DILS 2018, held in Hannover, Germany, in November 2018. The 5 full, 8 short, 3 poster and 4 demo papers presented in this volume were carefully reviewed and selected from 22 submissions. The papers are organized in topical sections named: big biomedical data integration and management; data exploration in the life sciences; biomedical data analytics; and big biomedical applications.