Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy. - Enables more effective study design and methods application in behavioral epigenetics research across human and animal models - Examines findings in human behavioral epigenetics to-date - Features contributions from leading international researchers in behavioral epigenetics

Embark on an illuminating voyage through the biological foundations of human nature and development with Psychobiological Footprints through Human Development. This unique volume unveils the intricate dance between genetics, neuroscience, and environment, offering a holistic understanding of how we become who we are. This comprehensive book examines the psychobiological, neuroendocrine, and epigenetic mechanisms that regulate developmental processes in typical development and under conditions of developmental risk. Moving within a dynamic systems epistemic framework and capitalizing from the heritage of the infant research field, it provides a solid framework for comprehending the interplay of nature and nurture. With a captivating blend of theoretical principles, processes, and contextual applications, this book transcends academic boundaries to empower anyone interested in the intricacies of human development. Psychobiological Footprints through Human Development is a guide to discovering how our life experiences contribute to making us who we are and therefore it is invaluable to graduate students in the fields of developmental psychology, neuroscience, genetics, and related disciplines. Delving into the biological roots of behaviour, cognition, and emotion, it will also equip practitioners, researchers, and educators with invaluable insights to enrich their practice.

Concepts and Theories of Human Development is the most comprehensive and in-depth overview of the foundational theoretical contributions to understanding human development and the influence of these contributions for contemporary research and application in developmental science. Since its initial publication in 1976, it has been an essential resource for students and professionals alike, and has become the go-to book for graduate students studying for their comprehensive exam on human development. In this new Fourth Edition, Richard M. Lerner concentrates his focus on advanced students and scholars already familiar with the basic elements of major psychological theories. The book discusses the assumptions involved in such topics as stage theories, the nature-nurture issue, the issue of continuity-discontinuity, and the important role of philosophical ideas about theories – in particular, metatheories – in understanding the links between theory and research. It particularly focuses on relational developmental systems (RDS) metatheory, exploring its roots in the 1930s, following its development into the present day, and contrasting it with the fundamentally flawed genetic reductionist models that continue to be circulated by scientists, the media, and the general public. It discusses implications of theory for research methods and for applications aimed at the promotion of health, positive development, and social justice among diverse people across the life span.

Epigenetic Shaping of Sociosexual Interactions: From Plants to Humans is the first attempt to interpret the higher social functions of organisms. This volume covers an extraordinarily wide range of biological research and provides a novel framework for understanding human-specific brain functions. Covers an extraordinarily wide range of biological research Provides a novel framework for understanding human-specific brain functions.

Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors as biomarkers and drug targets, (v) and the potential of epigenetics to advance personalized medicine. Here, readers will discover strategies to combat research challenges, improve quality of their epigenetic research and reproducibility of their findings. Additionally, discussion of assay and drug development for personalized healthcare pave the way for a new era of understanding in cardiovascular disease. - Offers a thorough overview of role of epigenetics mechanisms in cardiovascular disease - Includes guidance to improve research plans, experimental protocols design, quality and reproducibility of results in new epigenetics research - Explores biomarkers and drug targets of therapeutic potential to advance personalized healthcare - Features chapter contributions from a wide range of international researchers in the field

Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research. Thoroughly examines fundamental concepts in exercise and sports epigenetics, methods for new research, and known impacts for human physiology, disease, and clinical outcomes Discusses exercise and sports epigenetics in relation to metabolism, obesity, aging, immunity, and neurological disease, concussion, and sports doping, among other topics Includes preliminary information on exercise epigenetics and covid-19 infection Features chapter contributions from international experts in the field

Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects. - Offers a practical, interdisciplinary approach across epigenetics, epidemiology and various disease specialties - Applies epigenetic twin and family studies to determine the relationship between epigenetics and mental illness, cancers, cardiovascular disease, diabetes, obesity and high blood pressure, among other diseases and disorders - Features chapter contributions from a wide range of international researchers in the field

Drawing from philosophy, religion, biology, behavioral and social sciences, and the arts, The Routledge International Handbooks of Multidisciplinary Perspectives on Character Development, Volumes I and II, present cutting-edge scholarship about the concept of character across the life span, the developmental and contextual bases of character, and the key organizations of societal sectors, within and across nations, that promote character development in individuals, families, and communities. This first volume, Conceptualizing and Defining Character, explores the foundations of the field by providing an array of interdisciplinary approaches to character development, including economics, education, law, literature, military science, philosophy, and many more. With contributions from international experts, Volume I brings together cutting-edge research and discusses instances of character development, including civic character, courage, fairness, forgiveness, gratitude, morality, tolerance, and thankfulness. This comprehensive publication is an essential reference for researchers and graduate students in behavioral sciences, biology, philosophy, theology, and economics, as well as practitioners leading or evaluating character education or character development programs around the world. Find Volume II: Moderators, Threats, and Contexts here: www.routledge.com/9781032172453

Genome Stability: From Virus to Human Application, Second Edition, a volume in the Translational Epigenetics series, explores how various species maintain genome stability and genome diversification in response to environmental factors. Here, across thirty-eight chapters, leading researchers provide a deep analysis of genome stability in DNA/RNA viruses, prokaryotes, single cell eukaryotes, lower multicellular eukaryotes, and mammals, examining how epigenetic factors contribute to genome stability and how these species pass memories of encounters to progeny. Topics also include major DNA repair mechanisms, the role of chromatin in genome stability, human diseases associated with genome instability, and genome stability in response to aging. This second edition has been fully revised to address evolving research trends, including CRISPRs/Cas9 genome editing; conventional versus transgenic genome instability; breeding and genetic diseases associated with abnormal DNA repair; RNA and extrachromosomal DNA; cloning, stem cells, and embryo development; programmed genome instability; and conserved and divergent features of repair. This volume is an essential resource for geneticists, epigeneticists, and molecular biologists who are looking to gain a deeper understanding of this rapidly expanding field, and can also be of great use to advanced students who are looking to gain additional expertise in genome stability. - A deep analysis of genome stability research from various kingdoms, including epigenetics and transgenerational effects - Provides comprehensive coverage of mechanisms utilized by different organisms to maintain genomic stability - Contains applications of genome instability research and outcomes for human disease - Features all-new chapters on evolving areas of genome stability research, including CRISPRs/Cas9 genome editing, RNA and extrachromosomal DNA, programmed genome instability, and conserved and divergent features of repair