Mental health researchers are increasingly looking towards digital health tools to gather day-to-day lived experiences of people living with mental health conditions, by using apps and wearable devices complementing episodic clinical assessments. One of the key goals of collecting longitudinal real-world multimodal data (RWD) is to help build personalized computational models that may help explain the heterogeneity in clinical outcomes, mechanisms of action, and pathophysiology of mental health disorders across individuals.

Psychotic disorders are a group of severe mental disorders which affects 2-3% of the population and constitutes one of the leading causes of disability worldwide. Early intervention (EI) represents a major paradigm shift in psychiatric service and has been demonstrated to be effective in outcome improvement for first-episode psychosis (FEP) and at-risk mental state (ARMS). However, despite the promising findings, evidence has shown that a significant proportion of early psychosis patients still experience suboptimal clinical outcomes (such as high relapse risk, partial remission, early-onset treatment resistance, persistent negative symptoms, etc.), functional impairment and cognitive dysfunction. Further research clarifying the complex inter-relationships among symptomatology, psychosocial functioning, and cognitive deficits in the early illness course as well as evaluating effects of EI on further improvement on clinical, functional, and cognitive outcomes in patients with early psychosis would therefore facilitate development of next-generation EI service to enhance short-term treatment outcomes and long-term prognosis. This Research Topic aims to further our understanding of the complex relationships between symptomatology, psychosocial functioning and cognitive impairment in the early course of psychotic disorders, including first-episode psychosis (FEP) and at-risk mental state and to evaluate the effects of early intervention, either in terms of specific treatment modalities or in the comprehensive service framework, on further improvement in clinical, functional, and cognitive outcomes in patients with early psychosis.

Work-related factors have implications for health and wellbeing. Due to the amount of time spent at the workplace and the impact of work on health over an individual’s life course, the workplace has evolved as an important arena for population health promotion. Risk factors within the physical and psychosocial working environment, as well as inadequate organizational support, are associated with increasing work-related health problems, which result in psychosocial and economic implications for the individual, the family, the organization and the society. Recent estimates revealed an increasing level of sickness absence due to work related factors, among others. In recognition of the importance of worker health and a healthy working life, but also in line with numerous occupational health goals, many organisations set aside significant amounts of financial resources annually to promote work well-being. However, studies have shown that despite this positive disposition among employers, both employee participation and the impact of such programs remain minimal. According to the Ottawa declaration for health promotion and the Luxembourg declaration for Workplace Health Promotion (WHP), WHP should be strategic. It is recommended that WHP be conducted in a systematic and continuous process of needs analysis, priority setting, planning, implementation and evaluation. Unfortunately, available studies show that many companies have policies currently in place but lack knowledge regarding proper implementation and evaluation. The foregoing phenomenon raises questions regarding the level of knowledge of and attitudes towards WHP among people in management positions. This Research Topic aims to address factors affecting workplace health promotion. - What does WHP mean for employers? - What forms of WHP packages exist? - Is there evaluation and follow up of such interventions? - What are the barriers and facilitators relating to the uptake of WHP interventions among employees? - Do people in relevant managerial positions possess adequate knowledge regarding WHP? Manuscripts that explore factors crucial for WHP, including individual and organizational level factors, crucial for WHP are welcomed. Manuscripts on barriers, evidence-based interventions, best practices, analysis of existing policy documents and those with a life course perspective etc. are also welcomed. Manuscripts can be of national, international and global perspectives.

Digital Therapeutics for Mental Health and Addiction: The State of the Science and Vision for the Future presents the foundations of digital therapeutics with a broad audience in mind, ranging from bioengineers and computer scientists to those in psychology, psychiatry and social work. Sections cover cutting-edge advancements in the field, offering advice on how to successfully implement digital therapeutics. Readers will find sections on evidence for direct-to-consumer standalone digital therapeutics, the efficacy of integrating digital treatments within traditional healthcare settings, and recent innovations currently transforming the field of digital therapeutics towards experiences which are more personalized, adaptable and engaging. This book gives a view on current limitations of the technology, ideas for problem-solving the challenges of designing this technology, and a perspective on future research directions. For all readers, the content on cultural, legal and ethical dimensions of digital mental health will be useful. Gives a comprehensive overview of the field of digital therapeutics and research on their efficacy, effectiveness, scalability and cost-effectiveness Introduces novel directions in which digital therapeutics are currently being extended, including personalized interventions delivered in real-time Reviews important considerations surrounding digital therapeutics, including how they can be monetized and scaled, ethical issues, cultural adaptations, privacy and security concerns, and potential pitfalls