This thorough introductory volume presents the background, applications, and stepwise directions for standard DNA and RNA isolation techniques. Unlike a kit chemistry approach, this book provides a breadth of information necessary for junior or non-expert researchers to learn and apply these techniques in their work. An accessible, indispensable how-to guide for researchers in immunology, molecular biology, zoology, forensic science, genetics, botany, neuroscience, physiology, and others.

As global criminology evolves, new questions arise. How can policymakers and law enforcement agencies leverage criminological insights to formulate effective crime prevention strategies? How do international collaborations in forensic science contribute to a more robust global criminal justice framework? Cases on Forensic and Criminological Science for Criminal Detection and Avoidance beckons readers into the fascinating world of forensic science and criminology. Distinguished authors span multi-level experience as practitioners, researchers, and academics, and they examine the multifaceted dimensions of criminal detection and avoidance. Contributors, hailing from globally recognized institutions such as the British Criminology Association, Chartered Society of Forensic Sciences, and American Criminology Association, navigate the complex intersections of forensic science and criminology, exploring the latest criminal detection and avoidance advancements. Moreover, the book examines the practical implications of research findings. This book is ideal for academics, practitioners, policymakers, students, and professionals in criminology, forensic science, and criminal justice seeking a comprehensive exploration of contemporary criminal detection and avoidance issues.

Medical Microbiology deals with the study of microorganisms that colonize or infect humans. It studies the pathogenesis and epidemiology of these microorganisms with practical applications in diagnosis, treatment and prevention of diseases (infectious diseases, infection-related cancer, dysbiosis related diseases, etc.,). In the past two decades, its expansion is essentially due to the great advances in related fields such as immunology, genetics, bioinformatics, science, technology, engineering and mathematics. New scientific knowledge and understanding make possible new applications. Nevertheless, it becomes a challenge due to lack of expertise to analyze fast-growing data and to translate them in clinical practice and medical education. The pace and sophistication of advances in all scientific disciplines applied to medical microbiology call for a comprehensive and integrative understanding of the overall knowledge development in the different related fields (immunology, genetics, bioinformatics, science, technology, engineering and mathematics, etc.,). In light of this, the main goal of this topical collection is to bridge the gap between all these fields. Each article in this compilation is a stand‐alone text based on an integrative review, which highlights advances in molecular diagnosis and epidemiology of human pathogens. It also helps researchers and practitioners to access and scrutinize the fast expanding knowledge. This research topic in medical microbiology provides an updated core of basic knowledge critical to clinical practice in medicine. It is designed for physicians, researchers, educators, residents, Lab technicians, undergraduate and graduate students. Each article deals with an important human pathogen. It uses a multidisciplinary approach integrating new advances, especially in genetics, bioinformatics, science, technology, engineering and mathematics. It provides an update of the current state-of-the-art scientific knowledge applied to molecular diagnosis and epidemiology of human pathogens. Rapid detection, accurate identification and typing of causative pathogens are necessary to optimize treatment, to trace pathogens and to study microbial population dynamics.

This comprehensive guide to gene cloning provides beginning and advanced readers with the background, standard techniques, practical applications, and ethical and safety considerations in the field. A one-stop reference for students, researchers in academia and industry, and anyone interested in a thorough but accessible overview.

The identification and quantification of material present and collected at a crime scene are critical requirements in investigative analyses. Forensic analysts use a variety of tools and techniques to achieve this, many of which use light. Light is not always the forensic analyst’s friend however, as light can degrade samples and alter results. This book details the analysis of a range of molecular systems by light-based techniques relevant to forensic science, as well as the negative effects of light in the degradation of forensic evidence, such as the breakage of DNA linkages during DNA profiling. The introductory chapters explain how chemiluminescence and fluorescence can be used to visualise samples and the advantages and limitations of available technologies. They also discuss the limitations of our knowledge about how light could alter the physical nature of materials, for example by breaking DNA linkages during DNA profiling or by modifying molecular structures of polymers and illicit drugs. The book then explains how to detect, analyse and interpret evidence from materials such as illicit drugs, agents of bioterrorism, and textiles, using light-based techniques from microscopy to surface enhanced Raman spectroscopy. Edited by active photobiological and forensic scientists, this book will be of interest to students and researchers in the fields of photochemistry, photobiology, toxicology and forensic science.

It’s alive! It’s alive! (Thanks to biochemistry, that is.) Biochemistry is the science of the chemical processes that allow for…well…life. If it moves, breathes, eats, or sleeps, biochemistry can probably explain how. So, it stands to reason that the fundamentals of biochemistry can get a little complicated. In Biochemistry For Dummies, you’ll explore the carbons, proteins, and cellular systems that make up the biochemical processes that create and sustain life of all kinds. Perfect for students majoring in biology, chemistry, pre-med, health-services, and other science-related fields, this book tracks a typical college-level biochemistry class. It simplifies and clarifies the subject with easy-to-follow diagrams and real-world examples. You’ll also get: Explorations of cell biology, carbohydrates, proteins, lipids, and other fundamental building blocks of life Discussions of the basic structures common to all living organisms Treatments of the microscopic details of life that make us all tick If you’re looking for a hand with some of the trickier parts of biochemistry—or you just need an accessible overview of the subject—check out Biochemistry For Dummies today!

Heres the expert guidance practitioners need to diagnose and treat the most commonly encountered infections! This fully revised and updated New Edition keeps readers current with the latest etiologic agents, the most appropriate diagnostic tests, and the most effective management options. The 2nd Edition features new chapters on Antimicrobial Agents for the Primary Care Physician and Prosthetic Joint Infections.

Introduces readers to the state of the art of omics platforms and all aspects of omics approaches for clinical applications This book presents different high throughput omics platforms used to analyze tissue, plasma, and urine. The reader is introduced to state of the art analytical approaches (sample preparation and instrumentation) related to proteomics, peptidomics, transcriptomics, and metabolomics. In addition, the book highlights innovative approaches using bioinformatics, urine miRNAs, and MALDI tissue imaging in the context of clinical applications. Particular emphasis is put on integration of data generated from these different platforms in order to uncover the molecular landscape of diseases. The relevance of each approach to the clinical setting is explained and future applications for patient monitoring or treatment are discussed. Integration of omics Approaches and Systems Biology for Clinical Applications presents an overview of state of the art omics techniques. These methods are employed in order to obtain the comprehensive molecular profile of biological specimens. In addition, computational tools are used for organizing and integrating these multi-source data towards developing molecular models that reflect the pathophysiology of diseases. Investigation of chronic kidney disease (CKD) and bladder cancer are used as test cases. These represent multi-factorial, highly heterogeneous diseases, and are among the most significant health issues in developed countries with a rapidly aging population. The book presents novel insights on CKD and bladder cancer obtained by omics data integration as an example of the application of systems biology in the clinical setting. Describes a range of state of the art omics analytical platforms Covers all aspects of the systems biology approach—from sample preparation to data integration and bioinformatics analysis Contains specific examples of omics methods applied in the investigation of human diseases (Chronic Kidney Disease, Bladder Cancer) Integration of omics Approaches and Systems Biology for Clinical Applications will appeal to a wide spectrum of scientists including biologists, biotechnologists, biochemists, biophysicists, and bioinformaticians working on the different molecular platforms. It is also an excellent text for students interested in these fields.

Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. Molecular Diagnostics provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting. - Serves as the definitivereference for molecular pathologists worldwide - Covers a variety of molecular techniques including next generation sequencing, tumor somatic cell genotyping, infectious and genetic disease tecting, and pharmacogenetics - Discusses in the detail issues concerning quality assurance, regulation, ethics, and future directions for the science