The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

What is a stem cell? We have a basic working definition, but the way we observe a stem cell function in a dish may not represent how it functions in a living organism. Only this is clear: Stem cells are the engine room of multicelluar organisms—both plants and animals. However, controversies, breakthroughs, and frustration continue to swirl in eternal storms through this rapidly moving area of research. But what does the average person make of all this, and how can an interested scholar probe this vast sea of information? The Encyclopedia of Stem Cell Research provides a clear understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field. While stem cells are exciting alone, they are also clearly fueling the traditional areas of developmental biology and the field of regenerative medicine. These two volumes present more than 320 articles that explore major topics related to the emerging science of stem cell research and therapy. Key Features · Describes the different types of stem cells that have been reported so far and, where possible, tries to explain for each age, tissue, and species what is known about the biology of the cells and their history · Captures a strong sense of stem cell biology as it stands today and provides the reader with a reference manual to probe the mysteries of the field · Considers various religious, legal, and political perspectives · Includes selected reprints of major journal articles that pertain to the milestones achieved in stem cell research · Elucidates stem cell terminology for the nonscientist. Key Themes · Biology · Clinical Trials · Countries · Diseases · Ethics · History and Technology · Industry · Institutions · Legal · Organizations · People · Politics · Religion · States With contributions from scholars and institutional experts in the stem cell and social sciences, this Encyclopedia provides a primarily nonscientific resource to understanding the complexities of stem cell research for academic and public libraries.

This book presents important research advances in the study of stem cell research, as well as stem cell applications in diseases; stem cell transplantation; and pluripotent stem cells. Topics discussed herein include stem cell therapy for Alzheimer's disease; cancer stem cells and ncRNAs; stem cell applications in diabetes; image-guided stem cell therapy; cancer stem cells; stem cell transplantation; vascular tissue engineering; bone marrow-derived stem cells; and stem cell plasticity.

What is a stem cell? We have a basic working definition, but the way we observe a stem cell function in a dish may not represent how it functions in a living organism. Only this is clear: Stem cells are the engine room of multicelluar organisms—both plants and animals. However, controversies, breakthroughs, and frustration continue to swirl in eternal storms through this rapidly moving area of research. But what does the average person make of all this, and how can an interested scholar probe this vast sea of information? The Encyclopedia of Stem Cell Research provides a clear understanding of the basic concepts in stem cell biology and addresses the politics, ethics, and challenges currently facing the field. While stem cells are exciting alone, they are also clearly fueling the traditional areas of developmental biology and the field of regenerative medicine. These two volumes present more than 320 articles that explore major topics related to the emerging science of stem cell research and therapy. Key Features · Describes the different types of stem cells that have been reported so far and, where possible, tries to explain for each age, tissue, and species what is known about the biology of the cells and their history · Captures a strong sense of stem cell biology as it stands today and provides the reader with a reference manual to probe the mysteries of the field · Considers various religious, legal, and political perspectives · Includes selected reprints of major journal articles that pertain to the milestones achieved in stem cell research · Elucidates stem cell terminology for the nonscientist. Key Themes · Biology · Clinical Trials · Countries · Diseases · Ethics · History and Technology · Industry · Institutions · Legal · Organizations · People · Politics · Religion · States With contributions from scholars and institutional experts in the stem cell and social sciences, this Encyclopedia provides a primarily nonscientific resource to understanding the complexities of stem cell research for academic and public libraries.

The SAGE Encyclopedia of Stem Cell Research, Second Edition is filled with new procedures and exciting medical breakthroughs, including executive orders from the Obama administration reversing barriers to research imposed under the Bush administration, court rulings impacting NIH funding of research based on human embryonic stem cells, edicts by the Papacy and other religious leaders, and the first success in cloning human stem cells. Stem cell biology is clearly fueling excitement and potential in traditional areas of developmental biology and in the field of regenerative medicine, where they are believed to hold much promise in addressing any number of intractable medical conditions. This updated second edition encyclopedia will expand on information that was given in the first edition and present more than 270 new and updated articles that explore major topics in ways accessible to nonscientists, thus bringing readers up-to-date with where stem cell biology stands today, including new and evolving ethical, religious, legal, social, and political perspectives. This second edition reference work will serve as a universal resource for all public and academic libraries. It is an excellent foundation for anyone who is interested in the subject area of stem cell biology. Key Features: Reader’s Guide, Further Readings, Cross References, Chronology, Resource Guide, Index A Glossary will elucidate stem cell terminology for the nonscientist Statistics and selected reprints of major journal articles that pertain to milestones achieved in stem cell research Documents from Congressional Hearings on stem cells and cloning Reports to the President’s Council on Bioethics, and more

This book is an updated reference for one of the most exciting field of biomedical researches- Stem Cell Research and its therapeutic applications. Stem cell research holds great promise for the treatment of many human diseases that currently lack effective therapies. The set of chapters in this book provide insights into both basic stem cell biology and clinical applications of stem cell-based cell replacement therapies for a variety of human diseases, including cardiovascular diseases, neurological disorders, and li ver degeneration. It also covers novel technologies for the culture and differentiation of both human embryonic stem cells and adult tissue stem cells. This book summarizes our current state of knowledge in stem cell research and integrates basic stem cell biology with regenerative medicine in an overall context. It is an essential reference for students, postdoctoral fellows, academic and industrial scientists, and clinicians. v Acknowledgements The editors would like to thank Ms. Jill Brantley, Rose Chavarin, Alina Haas, and Emily Sun for their administrative assistance and proof-reading of this book. We would also like to thank all the authors for their contributions. vii The editors wish to dedicate this book to our mentors Ron Evans, Fred Gage, and, in memory of Daniel E. Koshland, Jr. Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Acknowledgements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi 1 Retinal Pigment Epithelial Cells: Development In Vivo and Derivation from Human Embryonic Stem Cells In Vitro for Treatment of Age-Related Macular Degeneration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Dennis O. Clegg, David Buchholz, Sherry Hikita, Teisha Rowland, Qirui Hu, and Lincoln V.

Encyclopedia of Tissue Engineering and Regenerative Medicine, Three Volume Set provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the fields of tissue engineering and regenerative medicine Contains multimedia features, including hyperlinked references and further readings, cross-references and diagrams/images Represents the most comprehensive and exhaustive product on the market on the topic