From classic MEN syndromes to various germline and somatic mutations in sporadic tumors In these times, a book should aspire to present the most significant advances in the field, reflect the themes of the moment, and provide a useful compendium for future reference. This book accomplishes all three objectives by discussing the changing world of modern genetics in endocrine tumors and its impact on clinical practice. Clinicians have to incorporate modern genetics and systems biology in their daily practice. Educators and researchers have to introduce molecular pathways and their genetic variability in their teaching, as well as understanding of classic physiology and pathophysiology. Taking these aspects into account, the chapters in this book cover both the classic multiple endocrine neoplasia (MEN) syndromes, as well as newly described ones, such as Carney triad and Carney- Stratakis syndrome. Furthermore, the genetics of paragangliomas as well as thyroid, parathyroid, and pituitary tumors are examined. Outlining the latest research and its obvious implications for our understanding the genetics of endocrine tumor formation and molecular biology of cancer and their potential therapeutic implications, this book is not only useful for researchers but even more so for practicing clinicians, in particular internists, endocrinologists, oncologists, pediatricians, surgeons, pathologists, geneticists, and genetic counselors.

This book is composed of 13 informative chapters written by world-renowned healthcare providers and researchers in the fields of endocrinology, pharmacy, radiology, infertility, pediatrics, internal medicine, psychology and genetics. From topics covering psychosocial impacts to pharmacokinetic and homecare resources, the intent of this book is to provide guiding principles for a safe and informative transition of care for pediatric and adolescent patients with various familial endocrine cancer syndromes that are transitioning from pediatric to adult health care. It provides an in-depth exploration of the diagnostic and therapeutic strategies, survivorship navigation intervention, patient, caregiver and primary care provider challenges, and multidisciplinary care plans for conditions such as MEN1, MEN2 and other familial and genetic endocrine neoplasias. Familial Endocrine Cancer Syndromes: Navigating the Transition of Care for Pediatric and Adolescent Patients is a much-needed resource, as the literature currently lacks a comprehensive publication to facilitate pediatric patients’ transition to adult clinics and resources following endocrine cancer diagnosis and treatment.

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Greatly revised and expanded, Comprehensive Clinical Endocrinology, 3rd Edition, now includes detailed coverage of diabetes, making it a truly complete clinical reference. With a more detailed focus on each condition and new clinical treatment plans to assist in the long-term treatment of patients, this new edition contains the practical information readers need to know about every endocrine condition. Full-color illustrations throughout make it an attractive, useful resource for today's clinicians. Covers all endocrine disorders in detail, including diabetes. Features more than 250 superb, full-color line drawings, all updated and redrawn for this edition, plus 250 two-color illustrations and CD - Rom. Provides 20-40 carefully selected key references in each chapter, rather than cumbersome lists of 200 or more. Covers diabetes in great detail, making it an all - in - one clinical reference for disorders and diseases of the endocrine system. Emphasizes practical, clinical detail throughout, and discusses basic science where relevant. Includes Therapeutic Plan algorithms for every condition that show the various treatment options for patient care. Discusses diagnostic procedures in greater detail, giving clearer guidance on diagnosis of complex conditions. Features concise Patient Perspectives sections, providing details on the effects these conditions have on the patient, both psychological and physical.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. More than 1,500 Q&A and 450 full-color illustrations provide the ultimate review for the Anatomic Pathology Board Examination McGraw-Hill Specialty Board Review: Anatomic Pathology is the perfect way for residents to prepare for the Anatomic Pathology Board Examination and for practicing pathologists to prepare for recertification. You will find everything you need in one comprehensive, full-color review...multiple-choice questions with detailed answer explanations, hundreds of full-color illustrations, suggested readings, and case-based scenarios. FEATURES More than 1,500 multiple-choice questions and answers Answers to questions include discussion of the salient features of the entity, diagnostic pitfalls, and differential diagnosis; and an explanation of the incorrect choice More than 450 full-color, high-resolution gross and microscopic images Covers all areas of anatomic pathology practice, such as pulmonary, bone and soft tissue, immunopathology, and more Valuable review articles and references provided at the end of each chapter