Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. - Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations - Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers - Features chapter contributions from international researchers in the field

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**Selected for Doody's Core Titles® 2024 in Clinical Genetics** Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine. This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs. - Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice - Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine - Organized from system disorders to multi-system disorders that involve epigenetic aberrations - Examines the role of epigenetics in precision medicine

This open access book focuses on of the impact of endocrine disrupting chemicals (EDCs) on human reproduction. It comprehensively discusses the three most important topics in the field: the basic biology of EDCs; the effects of EDCs on human reproduction and human reproductive systems; and potential interventions and practical advice for dealing with the problems caused by EDCs. Presenting a translational approach to endocrine disrupting chemicals research, spanning both basic biology and clinical applications, the book provides a critical link between laboratory investigations and clinical practice. Written by international experts in the field, it is a valuable reference resource for gynaecologists, obstetricians, endocrinologists and experts in reproductive medicine, and a useful tool for anyone interested in the impact of the environment on human reproduction.

Systems Biology and Machine Learning Methods in Reproductive Health is an innovative and wide-ranging book that discovers the synergetic combination of disciplines: systems biology and machine learning, with an application in the field of reproductive health. This book assembles the expertise of leading scientists and clinicians to present a compilation of cutting-edge techniques and case studies utilizing computational methods to elucidate intricate biological systems, elucidate reproductive pathways, and address critical issues in the fields of fertility, pregnancy, and reproductive disorders. Bringing science and data science together, this groundbreaking book provides scientists, clinicians, and students with a step-by-step guide to uncovering the complexities of reproductive health through cutting-edge computational tools.

Introducing "The Role of Genetics in Fertility: Exploring the Link Between Genetics and Reproductive Health" Are you curious about the role genetics play in fertility? Do you want to understand how genetic disorders can impact your ability to conceive? Look no further than "The Role of Genetics in Fertility: Exploring the Link Between Genetics and Reproductive Health." This short read book delves into the fascinating world of genetics and its influence on fertility, providing valuable insights and information for anyone interested in reproductive health. Table of Contents: 1. Genetic Disorders and Infertility: Discover how genetic disorders can affect fertility and what steps can be taken to overcome these challenges. 2. Genetic Testing for Fertility: Learn about the various genetic tests available to assess fertility potential and identify any underlying genetic issues. 3. Preimplantation Genetic Testing: Explore the revolutionary technique of preimplantation genetic testing and its role in selecting embryos with the highest chance of successful implantation. 4. Genetic Markers for Fertility: Uncover the genetic markers associated with fertility and how they can be used to predict reproductive success. 5. Genetic Counseling for Infertility: Understand the importance of genetic counseling in helping individuals and couples make informed decisions about their fertility journey. 6. Epigenetics and Fertility: Delve into the field of epigenetics and its impact on fertility, including how epigenetic changes can affect assisted reproduction techniques. 7. Epigenetic Inheritance and Fertility: Learn about the potential inheritance of epigenetic changes and its implications for future generations. 8. Genetic Factors in Age-Related Infertility: Explore the genetic factors that contribute to age-related infertility in both men and women. 9. Genetic Clock and Female Fertility: Gain insights into the concept of the genetic clock and its role in female fertility decline. 10. Genetic Factors in Male Age-related Infertility: Discover how genetic factors can affect male fertility as they age. 11. Genetic Disorders and Assisted Reproduction: Understand the challenges and considerations when using assisted reproduction techniques in individuals with genetic disorders. 12. Preimplantation Genetic Diagnosis for Genetic Disorders: Learn about the process of preimplantation genetic diagnosis and its role in preventing the transmission of genetic disorders. 13. Genetic Counseling for Assisted Reproduction: Explore the importance of genetic counseling in assisted reproduction to ensure the best possible outcomes. 14. Genetic Variability and Fertility: Discover the significance of genetic variability in fertility and its impact on reproductive success. This title is a short read. A Short Read is a type of book that is designed to be read in one quick sitting. These no fluff books are perfect for people who want an overview about a subject in a short period of time. Table of Contents The Role of Genetics in Fertility Genetic Disorders and Infertility Genetic Testing for Fertility Preimplantation Genetic Testing Genetic Markers for Fertility Genetic Counseling for Infertility Epigenetics and Fertility Epigenetic Changes and Assisted Reproduction Epigenetic Inheritance and Fertility Genetic Factors in Age-Related Infertility Genetic Clock and Female Fertility Genetic Factors in Male Age-related Infertility Genetic Disorders and Assisted Reproduction Preimplantation Genetic Diagnosis for Genetic Disorders Genetic Counseling for Assisted Reproduction Genetic Variability and Fertility Genetic Diversity and Fertility Genetic Compatibility and Reproductive Success Gene Therapy and Fertility Gene Editing for Infertility Gene Therapy for Reproductive Disorders Personalized Medicine and Fertility Genetic Biomarkers for Treatment Response Pharmacogenetics in Fertility Treatments Ethical Considerations in Genetic Fertility Research Genetic Privacy and Confidentiality Genetic Discrimination and Reproductive Choices Future Directions in Genetic Fertility Research Frequently Asked Questions

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Approximately one in twenty men have sperm counts low enough to impair fertility but little progress has been made in answering fundamental questions in andrology or in developing new diagnostic tools or management strategies in infertile men. Many of these problems increase with age, leading to a growing population of men seeking help. To address this, there is a strong movement towards integrating male reproductive and sexual healthcare involving clinicians such as andrologists, urologists, endocrinologists and counselors. This book will emphasize this integrated approach to male reproductive and sexual health throughout the lifespan. Practical advice on how to perform both clinical and laboratory evaluations of infertile men is given, as well as a variety of methods for medically and surgically managing common issues. This text ties together the three major pillars of clinical andrology: clinical care, the andrology laboratory, and translational research.

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.