Winner of a HIGHLY COMMENDED AWARD in the Neurology category of the 2012 BMA Medical Book Competition. More than five million people die from stroke each year. Stroke is also the leading cause of adult disability, affecting over 20 million people worldwide, with two-thirds of stroke victims left permanently disabled. We now know that speed of intervention is critical and patient outcomes are determined by a very narrow therapeutic window, during which physicians need to be able to make their choice of treatment rapidly, based on the best evidence available. The purpose of this book is to review that evidence, for both medical and surgical therapies as well as preventative strategies, drawing on the expertise of leading international authorities to distinguish the issues for which there is a consensus on best practice from those for which the evidence remains inconclusive. For example, for patients with acute ischemic stroke the first choice is intravenous thrombolytic therapy, but does a treatment window of 0-3 hours deliver outcomes significantly better than one of 3-4.5 hours? Arterial hypertension is the single most important modifiable risk factor for ischemic stroke, but what are the effects of blood pressure reduction among acute stroke patients? How effective is blood pressure lowering in primary intracerebral hemorrhage? What are the arguments in favour of continuation versus temporary discontinuation of antihypertensive therapy immediately after acute ischemic stroke? Endovascular procedures (carotid angioplasty/stenting) are increasingly important but what do the data tell us about their safety? Or durability? How do they compare with carotid endarterectomy? The management of unruptured intracranial aneurysms is rife with controversies; clip, coil, wait and watch? The authors examine the evidence for and against. Other sections examine the impact of various risk factors, and special populations. A section on stroke after cardiovascular surgeries reviews the incidence and management of stroke following a whole range of procedures. Another examines special risks during pregnancy. Lastly, the book reviews our understanding of childhood stroke and presents current best practice recommendations for this most challenging group of patients.

The treatment of hypertension is now evolving into a decision-making process of ever greater complexity. Not only has the range of drugs available increased but so too has our knowledge of the diversity of individual patients' responsiveness to therapy, and the need to tailor their treatment with reference to a wide variety of additional factors. In order to provide effective patient care, the clinician needs to be aware of all the options available, but also of the evidence supporting their use and the extent to which that evidence justifies the choices made. In this new volume, leading authorities in their fields draw on the available evidence to provide answers to a series of key clinical questions facing the clinician treating hypertension: Should we treat prehypertension? How does the choice of therapy change in the presence of comorbidities such as obesity, ischemic heart disease, left ventricular hypertrophy, diabetes or cerebrovascular disease? Evidence-based Management of Hypertension provides answers to these and many other questions, as the authors present an expert analysis of the available evidence and offer authoritative recommendations for treatment planning. In each chapter, tables highlight evidence from a variety of sources, and every chapter concludes with a series of key practice points that present a summary of evidence-based recommendations for best practice, graded according to the quality of that evidence. For any clinician concerned with the care of the hypertensive patient, this volume will be a valuable aid to treatment planning and long-term management.

Practising evidence-based medicine necessarily depends on the clinician having access to the best evidence available, but in a fast-moving field, keeping up to date with the latest developments is a challenging prospect. In this new volume, leading experts focus on the most important clinical issues associated with the management of lipid disorders, evaluating and interpreting the evidence available to provide the reader with a reliable summary of our current knowledge. Topics covered include therapeutical strategies for managing hereditary lipid disorders, including familial hypercholesterolemia, both in adults and children, and familial combined hypercholesterolemia. The authors also evaluate the evidence for a link between inflammatory disease and cardiovascular risk; the metabolic syndrome and the interconnections between dyslipidemias and diabetes. They also look at therapeutic challenges such as the management of patients who are statin resistant, and the control of lipid levels in those suffering renal insufficiency. Tables highlight important data, evidence from trial results and expert reports, and each section concludes with a series of key points that present a summary of evidence-based recommendations for best practice, graded according to the quality of that evidence. Evidence-based Management of Lipid Disorders provides the busy clinician with a unique analysis of the data supporting current therapies and will help the reader formulate effective strategies for treating their own patients.

The clinical management of patients with diabetes is rapidly evolving. Evidence-based Management of Diabetes provides a succinct summary of a range of topics, including areas where there is already well developed evidence for a particular treatment, but also those areas where the evidence is perhaps doubtful or there is some associated controversy or ambiguity. Where possible throughout the book treatment recommendations are given based on the available evidence and practice guidelines. The book also highlights the gaps in evidence where further research is needed. In the practice of diabetes care, there are many issues influencing practitoners currently. This book addresses many of the most pertinent issues concerning delivery of diabetes care. The authors are internationally renowned experts in the field of diabetes care who successfully and succinctly present state-of-the-art reviews based on the medical evidence designed to help the clinician be as best informed as possible in the care of patients with diabetes.

This text addresses vascular anomalies and the management of these diverse and clinically challenging set of conditions which have significant impact on patient function, quality of life and, in certain cases, survival. The text covers each category and type of vascular anomaly and the unique diagnostic and therapeutic challenges they pose. The chapters will also include fundamental scientific literature pertaining to each specific condition to help clinicians and clinical researchers better assess and manage vascular anomalies of the head and neck. Each vascular condition will be supported with medical photographs and radiographic images, summaries of diagnostic and therapeutic options, a list of syndromes and genetic mutations known to be associated with each anomaly, case studies, and clinical and research pearls from national and international leaders in the field. Management of Head and Neck Vascular Anomalies: Evidenced-based Assessment will be an invaluable resource for otolaryngologists, plastic surgeons, general and general pediatric surgeons, orthopaedic surgeons, dermatologists, interventional radiologists, residents and fellows in these fields, and researchers with interest in vascular anomalies of the head and neck.

Accompanying CD-ROM contains video learning modules on gait and balance and dizziness, a dermatology quiz, and downloadable cognitive assessment tools, to hone clinical skills. File formats include QuickTime movies, PDFs, and HTML documents.

Master core content areas. Test your knowledge. Prepare for certification and clinical practice. Assure that you have the in-depth understanding of advanced pathophysiology, advanced pharmacology, advanced health assessment, diagnostic reasoning, clinical decision making, and the interplay between these concepts that are required for exam success. In addition to an-depth review of core content, you’ll also have access to Davis Edge, the online Q&A platform that creates quizzes based on your personal strengths and weaknesses and tracks your progress every step of the way. Approximately 240 questions in the book and 1,000 questions online at Davis Edge parallel the domain and content areas of the examination outlines of both the American Nurses Credentialing Center and the American Association of Critical Care. Answers and in-depth rationales for correct and incorrect responses advance your mastery and understanding. And, like the exam, the questions focus on analysis and synthesis of information rather than memorization.

For fifty years, experienced clinicians and physicians in training have relied on Swaiman's cornerstone text as their #1 source for authoritative guidance in pediatric neurology. Swaiman's Pediatric Neurology: Principles and Practice, 7th Edition, continues this tradition of excellence under the expert editorial direction of Drs. Stephen Ashwal and Phillip L. Pearl, along with a team of key leaders in the field who serve as associate and section editors in their areas of expertise. Thorough revisions—including new chapters, new videos, new editors, and expanded content—bring you up to date with this dynamic field. - Contains new sections on global child neurology and environment and brain development and a greatly expanded section on neurogenetics, in addition to new chapters on autoimmune epilepsies, immune-mediated movement disorders, and more. - Offers expanded online content, including additional figures, tables, and text, as well as new personal introductory videos by many chapter authors. - Covers new, emerging, or controversial topics such as COVID-19, teleneurology, environment and brain development, immune-mediated disorders of the nervous system, functional neurological disorders in children, nonverbal learning disorders, and the pharmacological and future genetic treatment of neurodevelopmental disabilities. - Provides authoritative coverage of perinatal acquired and congenital disorders, neurodevelopmental disabilities, extensive sections on pediatric epilepsy and movement disorders, nonepileptiform paroxysmal disorders, and disorders of sleep. - Features nearly 3,000 line drawings, photographs, tables, and boxes that highlight the text, clarify key concepts, and make it easy to find information quickly.

Fully revised throughout, the new edition of this concise textbook is aimed at doctors preparing to specialize in stroke care.