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Genre | : Science |
Author | : André Dallmann |
Publisher | : Frontiers Media SA |
Release | : 2022-06-06 |
File | : 129 Pages |
ISBN-13 | : 9782889763351 |
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Genre | : Science |
Author | : André Dallmann |
Publisher | : Frontiers Media SA |
Release | : 2022-06-06 |
File | : 129 Pages |
ISBN-13 | : 9782889763351 |
Genre | : Science |
Author | : Qiwei Yang |
Publisher | : Frontiers Media SA |
Release | : 2023-06-27 |
File | : 173 Pages |
ISBN-13 | : 9782832526569 |
The book, intended for biomedical researchers, attempts to foster a comprehensive understanding of the elements that impact scientific research, such as clinical trial design, communication, and publication methods. It introduces the process of idea generation and creative/critical thinking, leading to the development of key concepts that coalesce into theoretical constructs and working hypotheses. The book systematically delineates research phases associated with a bench-to-bedside translational approach, providing the full depth and breadth of drug discovery and development: design, synthesis, and optimization of drug candidates interacting with targets linked to diseases, as well as clinical trial design to acquire substantial evidence of efficacy and safety for candidate drugs in the target patient population. New and evolving topics such as artificial intelligence, machine and deep learning, drug repurposing approaches, and bioinformatics, are incorporated into the text as these features are becoming integrated into drug research and development. Additionally, it covers publication strategies, including literature search, manuscript preparation, data presentation, relevant discussion, editorial processes, elements of peer review, and bibliometrics. Finally, the book addresses grantsmanship, key strategies for building effective networks, mentorships, maintaining research integrity, and forging career advancement opportunities, including entrepreneurship.
Genre | : Medical |
Author | : Gowraganahalli Jagadeesh |
Publisher | : Springer Nature |
Release | : 2023-11-01 |
File | : 926 Pages |
ISBN-13 | : 9789819912841 |
**Selected for Doody's Core Titles® 2024 in Pharmacology**Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. - Presents the essential knowledge for effective practice of clinical pharmacology - Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology - Offers an extensive regulatory section that addresses US and international issues and guidelines - Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK
Genre | : Medical |
Author | : Shiew-Mei Huang |
Publisher | : Academic Press |
Release | : 2021-10-16 |
File | : 764 Pages |
ISBN-13 | : 9780128198841 |
Genre | : |
Author | : Lei Chen |
Publisher | : Springer Nature |
Release | : |
File | : 170 Pages |
ISBN-13 | : 9789819739219 |
This book provides a concise overview of recent advances in Pharmacokinetics (PK) and Pharmacodynamics (PD). The pharmacokinetics section covers the state of the art in Physiologically Based Pharmacokinetic (PBPK) modeling (Chapter 1) as well as the assessment of food effect on drug absorption using PBPK modeling (Chapter 2). Chapters 3 and 4 describe the recent development of Physiologically Based Finite Time Pharmacokinetic (PBFTPK) models and their applications to pharmacokinetic data. The pharmacodynamics section focuses on PK/PD modeling. Chapter 5 provides an overview of PK/PD modeling and simulation in clinical practice and studies. Chapter 6 deals with the subject/physiology variability issue encountered in PK/PD studies, while Chapter 7 reviews the influence of clinical pharmacology in the modernization of drug development and regulation. This book is an essential reference for pharmaceutical scientists.
Genre | : Science |
Author | : Panos Macheras |
Publisher | : Springer Nature |
Release | : 2023-05-26 |
File | : 208 Pages |
ISBN-13 | : 9783031295416 |
Genre | : Medicine |
Author | : |
Publisher | : |
Release | : 1996 |
File | : 1548 Pages |
ISBN-13 | : OSU:32436010438644 |
Genre | : Pesticides |
Author | : Robert Irving Krieger |
Publisher | : |
Release | : 2001 |
File | : 960 Pages |
ISBN-13 | : UOM:39015053145416 |