Worldwide, osteoarthritis is one of the most rapidly rising conditions associated with disability. For most people, it is a syndrome of joint pain and stiffness, with associated functional problems that have a substantial effect on quality of life. As well as expert advice on well-established diagnostic criteria and the latest practical treatment information, this comprehensive handbook provides: • updates on the genetics of the disease • novel concepts of the association between structural changes and pain • recent recommendations for the use of modern imaging modalities • the latest on intra-articular therapies • an insight into current developments in the field. For all healthcare professionals who have ever felt unable to provide effective therapy for this disease, or who have encountered negative patient and community attitudes to joint pain, 'Fast Facts: Osteoarthritis' is essential reading. Something can be done to help every person with osteoarthritis!

Not to broach the subject of excess weight with a patient is a dereliction of duty as a healthcare professional, say the authors of 'Fast Facts: Obesity'. "Patients who smoke are rapidly identified for intervention, and the same should be true of anyone who is obese". Every consultation is an opportunity to educate and encourage patients to pursue better health. 'Fast Facts: Obesity' is packed with practical advice on how best to support patients to improve their nutrition and levels of physical activity, and change their habits, with simple and achievable goals tailored to individual needs and concerns. This highly readable handbook also provides a comprehensive overview of: • the causes and consequences of obesity • the latest information on pharmacological and surgical options • the issues specific to the management of obesity in children, pregnant women and the elderly. The authors say: “The opportunity to educate others and exert influence can be leveraged at many levels, even with limited amounts of time.” Reading 'Fast Facts: Obesity' is an excellent starting point for any healthcare professional who wants to understand this major threat to human health and ultimately improve outcomes. Contents: • Patient assessment • Causes and science • Cardiometabolic consequences • Other consequences • Management: diet • Management: physical activity • Management: behavioral therapy • Pharmacological and surgical treatments • Children, the elderly and pregnant women • Management tools, prevention and advocacy • Useful resources • The health risks of excess weight figure

All health professionals, regardless of specialty, will care for patients with pain that has persisted for more than 6 months. This fully updated fourth edition of 'Fast Facts: Chronic and Cancer Pain', written by two internationally renowned experts in the field, is designed to bring busy health professionals up to speed with the latest information in this area, including: • Easy-to-read overviews of pain mechanisms • A practical approach to pain assessment • Developments in stepped care and multimodal management • The latest thinking on opioids With health services around the world responding to calls to improve the management of painful long-term conditions, develop preventive and cost-effective solutions, and respond to patient choice and voice, this easy-to-read fact-packed book is essential reading for all GPs, nurses, junior hospital doctors, physical therapists, clinical psychologists, occupational therapists, pharmacists, medical specialists and medical students wanting - and needing - to know more. Contents: • Definitions and mechanisms • Assessment of pain • Treatment options • Trigeminal neuralgia • Complex regional pain syndrome • Diabetic and postherpetic neuropathic pain Central pain • Persistent postsurgical pain • Cancer pain • Musculoskeletal pain • Visceral pain • Headache

Psoriasis can no longer be considered a mere skin disease - it is a spectrum of different conditions requiring a spectrum of different treatments. Yet the systemic and psychosocial consequences of the condition often go unrecognized. The fourth edition of this refreshingly readable handbook explores the potential to improve the quality of life of patients by reducing the range of comorbidities associated with psoriasis, including arthritis, cardiovascular disease and inflammatory bowel disease. Fast Facts: Psoriasis is packed with practical information on all aspects of this increasingly treatable disease, including: • a concise review of the immunologic and genetic aspects of the disease • a well-illustrated guide to clinical presentation and differential diagnosis • all management options, from topical treatments to current and emerging receptor-targeted therapies • a commonsense approach to management by rotating and combining therapies • a fully updated chapter on psoriatic arthritis 'Fast Facts: Psoriasis' is essential reading for the primary care team, dermatology trainees and specialists in cardiology, gastroenterology and rheumatology who want to learn all about psoriasis but have little time to spare. Contents: • Epidemiology and pathophysiology • Clinical presentation • Differential diagnosis • General management approach • Topical Therapy • Phototherapy and photochemotherapy • Systemic therapy • Receptor-targeted (biological) therapies • Psoriatic arthritis • Future trends • Useful resources

'Fast Facts: Ankylosing Spondylitis' is a practical, fact-filled handbook for health professionals who need to update their knowledge of this disorder for the benefit of the patients in their care. • Provides a concise overview of the clinical features of the disease and differential diagnosis • Includes the most recent information on the genetic basis of this disorder • Covers the various management options including physical therapy, non-steroidal anti-inflammatory agents, and disease-modifying drugs • Highlights recently developed biological agents In addition to providing a wealth of practical information for use in patient care, this text reviews future directions for investigation and management of this debilitating disease. Contents: • The spectrum of spondylarthropathies • Genetic aspects • Epidemiology and socioeconomic impact • Clinical features • Assessment • Physical therapy • Non-steroidal anti-inflammatory drug therapy • Disease-controlling antirheumatic therapy • Future trends • Useful resources

This new edition of 'Fast Facts: Soft Tissue Disorders' is written from the combined perspectives of rheumatology, orthopaedics and sports medicine and is designed to provide the primary care specialist with a well- rounded and highly practical 'handbook' on diagnosis, management and patient involvement in recovery. The structure of all the major soft tissues and their common pathologies and disorders are covered here and each condition covered includes a set of practical exercises for the patient. • Includes two entirely new chapters covering local injection therapies and anterior knee pain • Covers common pathologies and disorders of all major soft tissues as encountered in the primary care setting • Packed with practical advice including patient involvement in recovery and management of outcomes expectations Contents: • Pathophysiology and epidemiology • Classification and diagnosis • Management guidelines • Local injection therapies • Ankle sprains • Achilles tendinopathies • Plantar fasciitis • Anterior knee pain • Lateral epicondylitis (tennis elbow) • Shoulder disorders • Polymyalgia rheumatica • Fibromyalgia and regional myofascial pain syndromes • Future trends

Cigarette smoking is one of the most significant preventable causes of death and illness in the world. Given the wide-ranging effects smoking has on many disease processes, it is essential that clinicians understand: • the short- and long-term effects of smoking on the body • the benefits of smoking cessation • why smokers find it difficult to stop • the role of clinicians in promoting and supporting smoking cessation • the treatments available to help smokers overcome their addiction. 'Fast Facts: Smoking Cessation' meets these needs: here, in one place, you will find all the information you need on smoking, tobacco addiction and how best to treat the addiction. Ultimately, the best reason for reading this book is to help your patients who smoke to change their behavior for the better and sustainably. Every GP and support clinic will benefit from this edition, filled with tips, advice and treatment aids for the clinical team. Contents: • Cigarettes as a nicotine delivery system • Smoking patterns • Social, psychological and economic influences on smoking • Effects of smoking and smoking cessation • Addiction to cigarettes • The clinician and smoking • Treatments to aid smoking cessation • Future trends

Biosimilars have been in clinical use for more than 10 years, and evidence from more than 700 million patient-days’ exposure shows that approved biosimilars can be used as safely and effectively as their originator biologics. And yet concerns about these drugs persist, particularly in therapy areas where they are recent additions to the formulary. It is vital to address these concerns so that clinicians can prescribe biosimilars with confidence, realizing substantial cost savings and improving patient access to effective treatments. 'Fast Facts: Biosimilars' provides a comprehensive yet concise explanation of biosimilars: what they are, how they are regulated, and how they are used in clinical practice. It is ideal for healthcare professionals and decision makers who want to understand biosimilars and the key concerns and controversies around these valuable products. Contents: 1 - An introduction to biologics and biosimilars 2 - Why do we need biosimilars? 3 - How is the quality of biosimilars assured? 4 - How is the efficacy and safety of biosimilars ensured? 5 - What has been the experience with biosimilars to date? 6 - The future of biosimilar medicines 7 - How do I use biosimilar medicines?

Most hemorrhagic problems are emergencies, requiring rapid diagnosis and prompt management to stop bleeding. In some cases, such as nose bleeds, large bruises and heavy menses, it is the clinician’s responsibility to discern whether the patient has a clinically significant bleeding disorder that may predispose to excessive or potentially serious bleeding. 'Fast Facts: Bleeding Disorders' keeps a complex subject simple and clinically oriented. The authors have made numerous updates to this second edition to ensure it provides essential information in a readily accessible format. Highlights include: • An expert overview of normal hemostasis • A clear assessment pathway, from taking an accurate history and focused clinical examination, to essential laboratory investigations • Objective criteria for diagnosing hereditary hemorrhagic telangiectasia • The latest guidelines on diagnosing and treating primary immune thrombocytopenia • A discussion of the benefits of prophylaxis in patients with hemophilia • Updated methods for evaluating and treating bleeding disorders in pregnancy • An overview of the scoring system for disseminated intravascular coagulation • Information on the latest anticoagulants and antithrombotics, including bleeding risks and strategies to control bleeding. 'Fast Facts: Bleeding Disorders' remains a comprehensive up-to-date reference that reflects the latest research and clinical guidelines. It will assist primary care providers, physician assistants, nurse-clinicians, pharmacists, residents and doctors in training as they confront the challenges of controlling bleeding in patients with hemophilia, von Willebrand disease, platelet disorders and thrombosis, or as a result of antithrombotic or anticoagulant therapy. It is a small book packed with important information, designed to swiftly improve patient treatment and outcomes. Contents: • Normal hemostasis • Assessment of bleeding symptoms • Vascular purpuras • Platelet disorders • Pharmacological hemostatic products • Hemophilia • von Willebrand disease • Uncommon congenital coagulation disorders • Liver and kidney disorders • Pregnancy • Perioperative bleeding • Disseminated intravascular coagulation • Anticoagulants and antithrombotic agents • Useful resources

Orthopaedic and Trauma Nursing provides practitioners working in orthopaedic and musculoskeletal trauma settings with the essential evidence, guidance and knowledge required to underpin effective practice. This comprehensive and contemporary textbook explores the variety of adult and paediatric clinical settings where orthopaedic and trauma practitioners work, including acute wards, clinics, community hospitals, nursing homes and patients' homes. Divided into 5 sections, this book looks at: key issues in orthopaedic and musculoskeletal trauma care; specialist practice issues; common orthopaedic conditions and their care and management; musculoskeletal trauma care; and care of children and young people. Suitable for students at degree level as well as those clinicians practicing in more advanced orthopaedic and trauma care roles, Orthopaedic and Trauma Nursing is a foremost authority on orthopaedic and musculoskeletal practice for both students and practitioners. Orthopaedic and Trauma Nursing: Is strongly supported by the latest evidence, with chapters summarizing evidence, with reference to relevant and seminal research Offers practical guidance based on the relevant evidence Focuses on the perspective of the patient with patient narrative and case studies throughout Includes a section specifically dealing with children and young people