Cancer is a group of different diseases (over 100) characterised by uncontrolled growth and spread of abnormal cells. Cancer can arise in many sites and behave differently depending on its organ of origin. If a cancer spreads (metastasises), the new tumour bears the same name as the original (primary) tumour. Significant progress has been made in recent years in the battle against cancer and in understanding its underlying biological mechanisms. This research progress has resulted in many experimental treatments and cures which establish hope for wide-spread cures. This book brings together important research from around the world in this frontal field.

Advances in cancer research over the recent decades have been plentiful and often successful, with 5 year survival rates increasing almost uniformly across the board. The advent of new technologies has presented solutions for yesterday’s barriers to research, allowing us to leap forward in our ability to prevent, diagnose, and treat various cancers. Developments in omics studies has provided new insights into the underlying molecular basis of different cancers and their subtypes, greatly enhancing our understanding of the vast heterogeneity that exists. Progress in our ability to diagnose and detect early-stage cancers has resulted in numerous screening and prevention programs. Novel imaging technologies allow us to study and comprehend cancers with greater clarity than ever before. Although the field, as a whole, has experienced many successes, arduous challenges must be overcome in order to see continued success. The truth of the matter is cancer related deaths continue to rise in number worldwide, especially in lower- and middle-income countries. It is evident that there is still a lot of work to be done. This Frontiers in Oncology Special Issue marks the 1st edition of a collection of selected articles published in the journal over the course of the previous calendar year, highlighting ongoing research and advances being carried out in the different disciplines of cancer research.

Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology researchers. The fourth volume of the book brings forth reviews on biomarkers and new drugs used for treating gastrointestinal cancer and breast cancer. The volume also covers the topics of adjuvant therapy, cancer nanodrugs and the role of adiponectin and dicycloplatin in cancer therapy.

Advances in Cancer Research, Volume 160, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research, with this updated edition covering PFKP: More Than Phosphofructokinase, Setting sail: maneuvering SHP2 activity and its effects in cancer, Mechanical factors driving cancer progression, Microsomal Glutathione Transferase 1 in Cancer and the Regulation of Ferroptosis, Lnc-ing epigenetic mechanisms with autophagy and cancer drug resistance, Head and Neck Cancer Treatment in the Era of Molecular Medicine, Applications of Tissue-Specific and Cancer-Selective Gene Promoters for Cancer Diagnosis and Therapy, and more. Provides the latest information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

First multi-year cumulation covers six years: 1965-70.

'A fascinating book . . . Bhaskar is a reassuringly positive and often witty guide' Observer 'A fascinating, must-read book covering a vast array of topics from the arts to the sciences, technology to policy. This is a brilliant and thought-provoking response to one of the most critical questions of our age: how we will come up with the next generation of innovation and truly fresh ideas?' Mustafa Suleyman, cofounder of DeepMind and Google VP 'Have "big ideas" and big social and economic changes disappeared from the scene? Michael Bhaskar's Human Frontiers is the best look at these all-important questions.' Tyler Cowen, author of The Great Stagnation and The Complacent Class 'Michael Bhaskar explores the disturbing possibility that a complacent, cautious civilization has lost ambition and is slowly sinking into technological stagnation rather than accelerating into a magical future. He is calling for bold, adventurous innovators to go big again. A fascinating book' Matt Ridley, author of How Innovation Works Where next for humanity? Is our future one of endless improvement in all areas of life, from technology and travel to medicine, movies and music? Or are our best years behind us? It's easy to assume that the story of modern society is one of consistent, radical progress, but this is no longer true: more academics are researching than ever before but their work leads to fewer breakthroughs; innovation is incremental, limited to the digital sphere; the much-vaunted cure for cancer remains elusive; space travel has stalled since the heady era of the moonshot; politics is stuck in a rut, and the creative industries seem trapped in an ongoing cycle of rehashing genres and classics. The most ambitious ideas now struggle. Our great-great-great grandparents saw a series of transformative ideas revolutionise almost everything in just a few decades. Today, in contrast, short termism, risk aversion, and fractious decision making leaves the landscape timid and unimaginative. In Human Frontiers, Michael Bhaskar draws a vividly entertaining and expansive portrait of humanity's relationship with big ideas. He argues that stasis at the frontier is the result of having already pushed so far, taken easy wins and started to hit limits. But new thinking is still possible. By adopting bold global approaches, deploying cutting edge technology like AI and embracing a culture of change, we can push through and expand afresh. Perfect for anyone who has wondered why we haven't gone further, this book shows in fascinating detail how the 21st century could stall - or be the most revolutionary time in human history.