Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. - Takes an integrated approach to infectious diseases - Includes contributions from leading authorities - Provides the latest developments in the field

In recent years, the ecology and evolution of infectious diseases has been studied extensively and new approaches to the study of host-pathogen interactions continue to emerge. At the same time, pathogen control in low-income countries has tended to remain largely informed by classical epidemiology, where the objective is to treat as many people as possible, despite recent research suggesting new opportunities for improved disease control in the context of limited economic resources. The need to integrate the scientific developments in the ecology and evolution of infectious diseases with public health strategy in low-income countries is now more important than ever. This novel text uniquely incorporates the latest research in ecology and evolutionary biology into the discussion of public health issues in low-income countries. It brings together an international team of experts from both universities and health NGOs to provide an up-to-date, authoritative, and challenging review of the ecology and evolution of infectious diseases, focusing on low-income countries for effective public health applications and outcomes. It discusses a range of public health threats including malaria, TB, HIV, measles, Ebola, tuberculosis, influenza and meningitis among others.

Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pathogens. Fully updated and revised, this new edition presents the consequences of such diseases, the evolution of infectious diseases, the genetics of host-pathogen relationship, and the control and prevention strategies that are, or can be, developed. This book offers valuable information to biomedical researchers, clinicians, public health practitioners, decisions-makers, and students and postgraduates studying infectious diseases, microbiology, medicine, and public health that is relevant to the control and prevention of neglected and emerging worldwide diseases. - Takes an integrated approach to infectious diseases - Provides the latest developments in the field of infectious diseases - Focuses on the contribution of evolutionary and genomic studies for the study and control of transmissible diseases - Includes updated and revised contributions from leading authorities, along with six new chapters

This book, originally published in 2004, is concerned with the links between human evolution and infectious disease. It has long been recognised that an important factor in human evolution has been the struggle against infectious disease and, more recently, it was revealed that complex genetic polymorphisms are the direct result of that struggle.

Plant Science, like the biological sciences in general, has undergone seismic shifts in the last thirty or so years. Of course science is always changing and metamorphosing, but these shifts have meant that modern plant science has moved away from its previous more agricultural and botanical context, to become a core biological discipline in its own right. However the sheer amount of information that is accumulating about plant science, and the difficulty of grasping it all, understanding it and evaluating it intelligently, has never been harder for the new generation of plant scientists or, for that matter, established scientists. And that is precisely why this Handbook of Plant Science has been put together. Discover modern, molecular plant sciences as they link traditional disciplines! Derived from the acclaimed Encyclopedia of Life Sciences! Thorough reference of up-to-the minute, reliable, self-contained, peer-reviewed articles – cross-referenced throughout! Contains 255 articles and 48 full-colour pages, written by top scientists in each field! The Handbook of Plant Science is an authoritative source of up-to-date, practical information for all teachers, students and researchers working in the field of plant science, botany, plant biotechnology, agriculture and horticulture.

The story of our evolutionary past is told in our genome sequence. Human Gene Evolution deals with the origins of human genes, describes their structure, function, organisation and expression. The text integrates our emerging knowledge of chromosome and genome structure, and discusses the nature of the mutational mechanisms underlying evolutionary change.

Widely used by students, residents, generalists, and specialists, Netter's Infectious Diseases, 2nd Edition delivers must-know information on infectious diseases in a highly illustrated, easily accessible format. Concise visual overviews of essential topics provide a convenient, trustworthy way to review the basics of a given infectious disease or issue or to share with patients or staff. Drs. Elaine Jong and Dennis Stevens cover the wide spectrum of illness and disease in this complex field using memorable illustrations by world-renowned artist Frank H. Netter and others, offering a time-saving, authoritative look at infectious disease risk factors, clinical presentations, pathophysiology, and more. - Covers major conditions and problems such as vaccine-preventable diseases, drug-resistant staph, community acquired pneumonia, surgical infections, pyelonephritis, viral hepatitis, and sexually transmitted infections—and provides updated approaches to diagnosis, treatment, prevention, and standards of care. - Includes new clinical vignettes added to most chapters - Provides updated and expanded coverage of emerging infectious diseases such as multidrug resistant tuberculosis (MDR-TB), neuroangiostrongyliasis (rat lungworm disease), Ebola virus, Severe Acute Respiratory Disease (SARS), Middle East Respiratory Syndrome (MERS), Coronavirus Infectious Disease-2019 (COVID-19), and novel influenza viruses including public health concerns. - Covers vector-borne diseases including malaria, yellow fever, Zika infections and congenital Zika syndrome, West Nile fever, Lyme disease, tick-borne encephalitis, and Chagas disease plus others. - New chapters on travelers' diarrhea, cholera, and primary amebic meningoencephalitis debut in the section on international travel and outdoor activities. - Contains memorable parasite life cycles and unforgettable parasite infection clinical vignettes. - Features unparalleled illustrations by Drs. Frank H. Netter, Carlos Machado, and others, as well as radiologic images. - Provides 24 printable patient education brochures in the digital ebook.

Molecular epidemiology has recently broaden its focuses due to the development of molecular tools but also by incorporating advances of other fields such as mathematical epidemiology, molecular ecology, population genetics and evolution. Facing new risks of emerging and re-emerging infectious diseases that are threats for humans and their livestock, the objectives of molecular epidemiology include: - the development of molecular tools, genotyping and gene expression - the incorporation of concepts and results of population genetics of infectious diseases - the integration of recent advances in theoretical epidemiology and evolutionary ecology of diseases - a better understanding of transmission for the development of risk factors analyses. This book will demonstrate how the latest developments in molecular tools and in epidemiology can be integrated with studies of host-pathogen interactions. Besides a strong theoretical component, there will also be an emphasis on applications in the fields of epidemiology, public health, veterinary medicine, and health ecology. Students and researchers in the fields of epidemiology, animal and human health, evolutionary ecology, parasitology are the main potential readers of the book, as well as a broader audience from veterinary medicine and conservation.

This book is a unique synthesis of the major concepts and methods in bacterial population genetics in infectious disease, a field that is now about 35 yrs old. Emphasis is given to explaining population-level processes that shape genetic variation in bacterial populations and statistical methods of analysis of bacterial genetic data. A "how to" of bacterial population genetics, which covers an extremely large range of organisms Expanding area of science due to high-throughput genome sequencing of bacterial pathogens Covers both fundamental approaches to analyzing bacterial population structures with conceptual background in bacterial population biology Detailed treatment of statistical methods