In this issue of Surgical Pathology Clinics, guest editor Dr. Ming Zhou brings his considerable expertise to the topic of Genitourinary Pathology. Top experts in the field cover key topics such as prostate cancer: update on grading and reporting; cribriform lesions of the prostate; urothelial carcinoma: divergent differentiation and variants; kidney tumors: new developments in existing WHO kidney tumor entities; and more. - Contains 13 relevant, practice-oriented topics including testicular tumors: new developments in germ cell tumors and sex cord stromal tumors; computational pathology in genitourinary pathology; molecular genetics of prostate cancer and role of genomic testing; evolving role of multiparametric MRI in prostate cancer diagnosis and reporting; and more. - Provides in-depth clinical reviews on current topics in genitourinary pathology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Surgical Pathology Clinics focuses on diseases of the genitourinary tract: Prostate, Kidney, Bladder, Testes, and Adrenals. As with all information in this series, presentations relate to the daily practice of surgical pathologists. A practical and innovative feature in this issue is the inclusion of several articles from the "clinician's perspective” in which an oncologist discusses the diagnosis of the disease and relates this to the information they require from the pathologist. Topics include: Morphologic updates in prostate pathology; Molecular updates in prostate pathology; Diagnosis of prostate carcinoma: A clinician's perspective; Commonly encountered renal neoplasms; Emerging entities in renal neoplasia; Diagnosis of renal cell carcinoma: A clinician's perspective; Morphologic and molecular characteristics of bladder cancer; Diagnosis of bladder carcinoma: A clinician's perspective; Overview of testicular neoplasia; Diagnosis of testicular cancer: A clinician's perspective; Overview of adrenal neoplasia; Diagnosis of adrenal carcinoma: A clinician's perspective; Benign lesions of the GU tract . Michelle Hirsch leads this issue with a group of expert genitourinary pathologists and oncologists.

This issue of Surgical Pathology Clinics, edited by Dr. Sean R. Williamson, will focus on Genitourinary Pathology. Topics include, but are not limited to, Large ductal lesions of the prostate; Update in hereditary renal cancer; Urothelial carcinoma variants; Non-germ cell tumors of the testis; Prostate cancer (grading); Prostate cancer (staging); Renal cancer; Testis grading and staging; Bladder grading and staging; "Man from Istanbul" lesions of the genitourinary tract; Mesenchymal tumors of genitourinary tract; Translational molecular updates in renal cancer; Pathologic reporting parameters most relevant to the urologist; and Pathologic reporting parameters most relevant to the medical oncologist.

In this issue of Surgical Pathology Clinics, guest editor Dr. Aatur D. Singhi brings his considerable expertise to the topic of Pancreatobiliary Neoplastic Pathology. Top experts in the field discuss precursor and malignant neoplasms (with mimics) such as molecular discoveries (e.g., IOPNs), neoadjuvant treatment histopathology (e.g., grading), immunohistochemical biomarkers (e.g., prognostic markers for neuroendocrine tumors), and more. - Contains 13 relevant, practice-oriented topics including the diagnostic challenge of evaluating small biopsies from the pancreatobiliary system; integrating molecular analysis to the pathologic evaluation of pancreatic cysts; the cytomorphologic and molecular assessment of bile duct brushing specimens; advances in the surgical approach to pancreatobiliary neoplasms; and more. - Provides in-depth clinical reviews on pancreatobiliary neoplastic pathology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Surgical Pathology Clinics, edited by Dr. John Hart, focuses on Liver Pathology. Topics include--but are not limited to--Hereditary cholestatic disorders; Autoimmunity in the liver; Fibrolamellar carcinoma; Hepatocellular adenoma; Infections/granulomas in the liver; HCV and direct acting antivirals; Lymphomas in the liver; Viral heaptitis; NASH; Drug induced liver injury; PBC and AIH; Liver transplant; Frozen sections of the liver; Hepatocellular carcinoma; and Cholangiocarcinoma.

Early identification and diagnosis by type and stage is the key to high survival rates with thyroid cancer. To present the pathologist with current clinical information on diagnosis, differential diagnosis, staging, and prognosis of thyroid cancers, topics presented are: Poorly differentiated thyroid carcinoma; Paraganglimoa; Immunohistochemical markers for evaluation and prognosis in thyroid carcinoma; Familial endocrine syndromes; Parathyroid enoplasia; Inflammatory lesions of the thyroid associated with cancer; Assessing biological aggression in adrenal cortical neoplasia; Pituitary neoplasia; and Pancreatic endocrine neoplasia. Peter Sadow, whose clinical practice and research involve studying the mechanisms of endocrine carcinogenesis through translational studies involving the proteomics and genomics of endocrine neoplasms, primarily of the thyroid and adrenal glands, leads this issue.

In this issue of Surgical Pathology Clinics, guest editor Dr. James Lewis, Jr. brings his considerable expertise to the topic of Sinonasal Pathology. Top experts discuss current research findings of internal and external sinonasal issues in pathology, including undifferentiated and poorly differentiated carcinomas; hamartomas; fungal infections and their differential diagnosis; adenocarcinomas; noninfectious inflammatory disorders; and more. - Contains 14 relevant, practice-oriented topics including papillomas; HPV and other viral-driven tumors; melanoma; neuropathology entities involving the sinonasal tract; and more. - Provides in-depth clinical reviews on sinonasal pathology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Surgical Pathology Clinics, edited by Dr. Vickie Jo, focused on Cytopathology. Topics include--but are not limited to--Head and Neck Cytology: HPV-Associated Carcinomas; Updates in Thyroid Cytology; Salivary Gland Cytopathology; Pulmonary Cytopathology; Updates in Effusion Cytology; Updates in Gynecologic Cytology; Diagnostic Advances in Urine Cytology; Renal Neoplasms; Pancreaticobiliary Cytology; Carcinoma of Unknown Primary; Soft Tissue Neoplasms; Primary Bone Tumors; Pediatric Cytopathology; Advances in Molecular Testing Techniques in Cytological Specimens; and Circulating Tumor Cells: Applications in Cytopathology.

In this issue, guest editors bring their considerable expertise to this important topic.Provides in-depth reviews on the latest updates in the field, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize

This issue of Surgical Pathology Clinics is devoted to Soft Tissue Tumors, the first in this series was presented in 2011. This issue addresses the most difficult diagnostic challenges and focuses on differential diagnosis in soft tissue tumors. Each presentation is accompanied by abundant histologic slides to display the diagnostic differences. Additionally, authors selected two to five diagnoses they find can be particularly difficult, with an emphasis on how to approach such lesions on biopsy samples where relevant and the role of ancillary studies. Topics include coverage of diagnostically challenging: Vascular lesions; Retroperitoneal “Fatty tumors of adults; Smooth muscle neoplasms; Chondro-osseous lesions of soft tissue; Pediatric tumors; Epithelioid tumors; Spindle cell neoplasms of the retroperitoneum; and Peripheral nerve sheath tumors. Also presented are: Non-mesenchymal mimics of benign and malignant soft tissue tumors; Soft tissue tumors with overlapping molecular findings; Recently characterized soft tissue tumors; Benign mimics of sarcoma; Advances in molecular methods in the analysis of soft tissue tumors and therapeutic implications; and Myoepithelial tumors: an update. Leona Doyle and Karen Fritchie lead this issue of experts in soft tissue pathology.