On the 8th of August 1900 outstanding German mathematician David Hilbert delivered a talk "Mathematical problems" at the Second Interna tional Congress of Mathematicians in Paris. The talk covered practically all directions of mathematical thought of that time and contained a list of 23 problems which determined the further development of mathema tics in many respects (1, 119]. Hilbert's Sixteenth Problem (the second part) was stated as follows: Problem. To find the maximum number and to determine the relative position of limit cycles of the equation dy Qn(X, y) -= dx Pn(x, y)' where Pn and Qn are polynomials of real variables x, y with real coeffi cients and not greater than n degree. The study of limit cycles is an interesting and very difficult problem of the qualitative theory of differential equations. This theory was origi nated at the end of the nineteenth century in the works of two geniuses of the world science: of the Russian mathematician A. M. Lyapunov and of the French mathematician Henri Poincare. A. M. Lyapunov set forth and solved completely in the very wide class of cases a special problem of the qualitative theory: the problem of motion stability (154]. In turn, H. Poincare stated a general problem of the qualitative analysis which was formulated as follows: not integrating the differential equation and using only the properties of its right-hand sides, to give as more as possi ble complete information on the qualitative behaviour of integral curves defined by this equation (176].

This book focuses on the modeling and mathematical analysis of stochastic dynamical systems along with their simulations. The collected chapters will review fundamental and current topics and approaches to dynamical systems in cellular biology. This text aims to develop improved mathematical and computational methods with which to study biological processes. At the scale of a single cell, stochasticity becomes important due to low copy numbers of biological molecules, such as mRNA and proteins that take part in biochemical reactions driving cellular processes. When trying to describe such biological processes, the traditional deterministic models are often inadequate, precisely because of these low copy numbers. This book presents stochastic models, which are necessary to account for small particle numbers and extrinsic noise sources. The complexity of these models depend upon whether the biochemical reactions are diffusion-limited or reaction-limited. In the former case, one needs to adopt the framework of stochastic reaction-diffusion models, while in the latter, one can describe the processes by adopting the framework of Markov jump processes and stochastic differential equations. Stochastic Processes, Multiscale Modeling, and Numerical Methods for Computational Cellular Biology will appeal to graduate students and researchers in the fields of applied mathematics, biophysics, and cellular biology.

The International Society for Analysis, its Applications and Computation (ISAAC) has held its international congresses biennially since 1997. This proceedings volume reports on the progress in analysis, applications and computation in recent years as covered and discussed at the 7th ISAAC Congress. This volume includes papers on partial differential equations, function spaces, operator theory, integral transforms and equations, potential theory, complex analysis and generalizations, stochastic analysis, inverse problems, homogenization, continuum mechanics, mathematical biology and medicine. With over 500 participants from almost 60 countries attending the congress, the book comprises a broad selection of contributions in different topics.

The biannual ISAAC congresses provide information about recent progress in the whole area of analysis including applications and computation. This book constitutes the proceedings of the third meeting.

The biannual ISAAC congresses provide information about recent progress in the whole area of analysis including applications and computation. This book constitutes the proceedings of the third meeting.

Nonlinear dynamical systems and the formation of spatio-temporal patterns play an important role in current research on partial differential equations. This book contains articles on topics of current interest in applications of dynamical systems theory to problems of pattern formation in space and time. Topics covered include aspects of lattice dynamical systems, convection in fluid layers with large aspect ratios, mixed mode oscillations and canards, bacterial remediation of waste, gyroscopic systems, data clustering, and the second part of Hilbert's 16th problem. Most of the book consists of expository survey material, and so can serve as a source of convenient entry points to current research topics in nonlinear dynamics and pattern formation. This volume arose from a workshop held at the Fields Institute in December of 2003, honoring Professor William F. Langford's fundamental work on the occasion of his sixtieth birthday. Information for our distributors: Titles in this series are copublished with the Fields Institute for Research in Mathematical Sciences (Toronto, Ontario, Canada).

Excellent reviews of the first edition (Mathematical Reviews, SIAM, Reviews, UK Nonlinear News, The Maple Reporter) New edition has been thoroughly updated and expanded to include more applications, examples, and exercises, all with solutions Two new chapters on neural networks and simulation have also been added Wide variety of topics covered with applications to many fields, including mechanical systems, chemical kinetics, economics, population dynamics, nonlinear optics, and materials science Accessible to a broad, interdisciplinary audience of readers with a general mathematical background, including senior undergraduates, graduate students, and working scientists in various branches of applied mathematics, the natural sciences, and engineering A hands-on approach is used with Maple as a pedagogical tool throughout; Maple worksheet files are listed at the end of each chapter, and along with commands, programs, and output may be viewed in color at the author’s website with additional applications and further links of interest at Maplesoft’s Application Center

This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included.This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research.

This volume contains the selected contributed papers of the BIOMAT 2010 International Symposium which has been organized as a joint conference with the 2010 Annual Meeting of the Society for Mathematical Biology (http: //www.smb.org) by invitation of the Director Board of this Society. The works presented at Tutorial and Plenary Sessions by expert keynote speakers have been also included. This book contains state-of-the-art articles on special research topics on mathematical biology, biological physics and mathematical modelling of biosystems; comprehensive reviews on interdisciplinary areas written by prominent leaders of scientific research groups. The treatment is both pedagogical and sufficiently advanced to enhance future scientific research