This book preparation is an effort made to cover the practicals of physical pharmaceutics to be performed during the B.Pharm curriculum. The practicals cover topics related to physical properties of liquids like surface tension, viscosity, density, pH, stability of suspensions. Special emphasis is given on the procedure of practicals which will be helpful for the teachers and students with greater ease of understanding the concepts of physical pharmaceutics. It was found that very few such books were available having practical matter as compared to the books having theory matter. So this book will be very helpful to academicians as well as the industry in understanding the concepts of physical pharmaceutics.

We are very pleased to put forth the first edition of 'Laboratory Manual of Physical Pharmaceutics I'. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various experiments in Physical Pharmaceutics I. The manual mainly includes the experiments through which the students will learn how the basic properties of drug like solubility, dissolution, can limit the bioavailability of drug and in turn the efficacy of the drug. The solubility enhancement techniques like reduction of particle size, use of solubilizing agents or prodrugs etc. are also discussed. The students will also learn about the importance of drug stability and how the parameters like temperature, pH, humidity and light can affect the drug stability. Physical pharmaceutics is very important subject which helps the researchers to design and formulate various dosage forms including its manufacturing aspects. The students will be proficient in handling various equipment used in physical pharmaceutics laboratory. The students will also be able to determine pKa, partition coefficient, surface tension, critical micelle concentration, HLB value, stability constant, buffer capacity, etc. in the laboratory. We have taken extra efforts to make the experiments simpler, easy to understand and perform. The graphs have also been provided wherever necessary. Each experiment is divided into sections like aim, practical significance, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, related questions, and references. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. We are very much thankful to the designer, publisher, printers and all the stakeholders for putting their efforts for successfully bringing this manual out for the students. Hope this manual will help the students to learn the concept, principles and perform the experiments. We wish them all the best!!!

We are very pleased to put forth the first edition of 'Laboratory Manual of Physical Pharmaceutics II'. This manual is prepared as per PCI Education Regulations, 2014 for Degree Course in Pharmacy. This manual is designed for 'outcome-based education' and each experiment is arranged in a uniform way such as practical significance, practical outcomes (PrOs) and its mapping with course outcomes, minimum theoretical background, resources used, procedure, precautions, observations, result, conclusion, references and related questions. A sincere attempt has been made through this manual to provide practical knowledge to the students related to various experiments in Physical Pharmaceutics II. The manual mainly includes the experiments through which the students will learn how the basic properties of drug like solubility, dissolution, can limit the bioavailability of drug and in turn the efficacy of the drug. The solubility enhancement techniques like reduction of particle size, use of solubilizing agents or prodrugs etc. are also discussed. The students will also learn about the importance of drug stability and how the parameters like temperature, pH, humidity and light can affect the drug stability. Physical pharmaceutics is very important subject which helps the researchers to design and formulate various dosage forms including its manufacturing aspects. The students will be proficient in handling various equipment used in physical pharmaceutics laboratory. The students will also be able to determine pKa, partition coefficient, surface tension, critical micelle concentration, HLB value, stability constant, buffer capacity, etc. in the laboratory. We have taken extra efforts to make the experiments simpler, easy to understand and perform. The graphs have also been provided wherever necessary. Each experiment is divided into sections like aim, practical significance, relevant course outcomes, practical skills, relevant affective domain related outcomes, practical outcomes, minimum theoretical background, requirements, related questions, and references. The manual has been designed with more emphasis on the practical skill improvement of the students so that the students can perform the practical with ease and comfort. We are very much thankful to the designer, publisher, printers and all the stakeholders for putting their efforts for successfully bringing this manual out for the students. Hope this manual will help the students to learn the concept, principles and perform the experiments. We wish them all the best!!!

This book is conceived to reflect the practical aspects of Industrial Pharmacy. The contents of this book are an integral part of the syllabi prescribed by Pharmacy Council of India and Indian universities. This practical book covers whole of the experimental component specified in the syllabus. Authors have made special attempts to cover all aspects ranging from preformulation studies, dosage form design, product manufacturing process and evaluation. This book only discusses relevant information and has been written in simple, straightforward language. The main motivation behind this book was to cover all the important practical aspects of Industrial Pharmacy I under one umbrella at an affordable price to encourage students to read and learn.

Physical pharmaceutics is a foundational area of pharmacy that deals with the principles underlying the physical and chemical properties of drugs and drug delivery systems. Here are some key topics typically covered in Physical Pharmaceutics I: The fundamental properties of drug substances such as solubility, stability, surface & interfacial phenomena, rheology, micrometrics, & complexation which will give a lead in formulating drug substances into suitable dosage forms. In addition, it includes ICH guidelines for stability testing and also suggestions for practical’s wherever necessary. Moreover, the language is so simple that grantees more clarity than brevity, We do hope the presentation will motivate self study.

An effort has been made to investigate the topic using terminology that is as straightforward as possible in order to make it more simply digestible for pupils. The book has a number of illustrations, such as flowcharts and diagrams that make it simple for students to comprehend complex ideas. It is the author's honest desire that both students and academicians would take something helpful away from reading this book. I am hoping that both the students and the teachers will have positive reactions to this book. We are open to hearing recommendations regarding any and all aspects of the profession. We take full responsibility for any deviations or errors that may have been overlooked, and we would be extremely appreciative if readers would bring them to our attention if they did occur.

"Physical Pharmaceutics for B Pharma 2nd Year: A Comprehensive Guide for Pharmacy Students" is a textbook designed to provide a solid understanding of the fundamental principles and practical applications in the field of physical pharmacy. The Indepth Content Covered in this book will help students to get a better insight into various areas of formulation research and development, and stability studies of pharmaceutical dosage forms. Tailored specifically for the BP403T course, this book serves as an essential guide for students pursuing pharmaceutical sciences.