Handbook of Proteolytic Enzymes, Second Edition, Volume 1: Aspartic and Metallo Peptidases is a compilation of numerous progressive research studies on proteolytic enzymes. This edition is organized into two main sections encompassing 328 chapters. This handbook is organized around a system for the classification of peptidases, which is a hierarchical one built on the concepts of catalytic type, clan, family and peptidase. The concept of catalytic type of a peptidase depends upon the chemical nature of the groups responsible for catalysis. The recognized catalytic types are aspartic, cysteine, metallo, serine, threonine, and the unclassified enzymes, while clans and families are groups of homologous peptidases. Homology at the level of a family of peptidases is shown by statistically significant relationship in amino acid sequence to a representative member called the type example, or to another member of the family that has already been shown to be related to the type example. Each chapter discusses the history, activity, specificity, structural chemistry, preparation, and biological aspects of the enzyme. This book will prove useful to enzyme chemists and researchers.

Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more. - The only comprehensive book on proteolytic enzymes - Includes 671 chapters, each written by experts in their field, on proteolytic enzymes from all groups of living organisms and the viruses, including those that are currently major targets of pharmaceutical research - Accompanying CD-ROM provides fully searchable text, 2D structures of peptidases in color and links directly to PubMed and MEROPS databases - Each chapter describes in detail the enzyme name, its history, activity and specificity, structural chemistry, preparation, biological aspects and distinguishing features - Over 1000 peptidases included

Recent developments in genetic engineering and protein chemistry are bringing ever more powerful means of analysis to bear on the study of enzyme structure. This volume reviews the most important types of industrial enzymes. In a balanced manner it covers three interrelated aspects of paramount importance for enzyme performance: three-dimensional protein structure, physicochemical and catalytic properties, and the range of both classical and novel applications.

How could be changed out of classical concept of ANATOMY (ana-tomos = to cut off in small pieces) which is one of the strongest imprinted scientific concept within the minds of all biologic scientists still by centuries, with the philosophical concept as ANATOMOLOGY? i.e. the Science of Anatomy, the Philosophical Science of the Anatomy, which in turn, could be synthesized by anatomists and philosophers alike!... Our endeavor is to find out a road between the two basic forms of human knowledge, an aurea mediocritas of dreaming pathway of any metaphysical living system… Anatomologist

To my mother Victoria, the greatest Incentor-Being throughout my life, and which proved to be more than any encouragement by creating the monumental opera of the AERA OF PHILOSOPHICAL SYSTEMS! Being and Edentation is a combination between Gnathology-Dentistry, as human pathology in total edentation with an interpretation between dentistry, philosophy, psychology, theology, in their videological togetherness. Video-Gnathologist

Could be re-thought and re-made another relationship between maximal Individuality of Human Being seen and analyzed as Dasein or Being and its maximal generality of the Species to whom belongs the Human Being, seen and analyzed as Sapiens?... Nevertheless, Sapiens means intelligence, means ability in creativity, whatever in science, technology, art or architecture, in writing books and building up schools, universities or libraries… However, the Book-in-itself, Buch-in-sich-selbst, can be seen as a Being / Dasein in motion and emotion… It would be logically or even rational to put in the same level of conceptological field, whatever in inwards field or outer field Being and Book, i.e., Dasein & Buch?... Moreover, The Being of Book, das Dasein des Büchers, could be re-asserted into the relationship between Books and Library, Büchern & Bibliothek, likewise Being & Species, or Dasein & Spezies, i.e., DASEIN & SAPIENS?... …Finally, our book will have the overall title, the general onoma as DASEIN & SAPIENS, including thus, Book, Being, Library, Species, Creativity, Inspiration, Intuition, Hardworking, Anonymity, Encouragements through myself, Humiliations, Underestimation, Rejections and Threatens… Booksologist

Industrial Enzymes for Biofuels Production: Recent Updates and Future Trends focuses on resolving existing bottlenecks in enzymes mediated biomass to biofuels production processes through updating recent scientific knowledge and technology developments. The book provides low cost sustainable approaches to lower the cost of enzymes production following different approaches. It is specifically focused on industrial aspects of enzymes used in biofuels production processes by presenting in-depth study of existing issues related to practical viability and long-term sustainability. The book covers detailed discussions on market scenario of industrial enzymes used in biofuels production processes and compares them on both lab and industrial scale. Users will find this to be a great resource that also helps them develop low cost green technologies for enzyme development in biofuels production. Includes recent updates in research and the technologies of industrial enzymes used in biofuels production process Describes various developed low-cost technologies for enzyme production Explores different, sustainable approaches currently being used

This book presents a comprehensive survey about the most recent developments in industrial applications, processing techniques and modifications of polymers from marine sources. It systematically introduces the reader to the biomaterials Chitin, Collagen, Alginates, Cellulose and Polyesters and links their interwoven industrial significance and environmental implications. The book elucidates the impact of industrial sourcing of the aquatic system for organic and inorganic matter on the environment and deepens the understanding of the industrial and economic significance of aquatic biopolymers. Further it addresses the question of how to balance the conservation of aquatic life and the industrial and economic interest in developing biodegradable alternatives for plastic. Thus the book will appeal to scientists in the field of chemistry, materials and polymer science as well as engineering.

It is the first time in human known history, when a viral disease, combining both epidemics with pandemics aggression, is seen, is analysed, is etymologized, pathogeneses through Philosophical Systems… It is possible such development of philosophical pathology? Of philosophical medicine? Of theoretical medicine? A conceptological medicine? And, all of the above questions getting together to the next row of questions, as such: A Philosophical System in Biology? A Philosophical System in Micro-biology? A Philosophical System in Viral Biology? A Philosophical System in Virusology? A Philosophical System in Pathology and Pharmacology? Yes, all of the above, true! It is the first time also, in human known history, when a such development in philosophy of science, has been correlated with the terrible crisis of Sapiens through Corona Virus illnesses, in this dramatic reciprocal pathologies… Coronavirus through Sapientologist

…Has our Species Sapiens a guardian angel around her? Eine Schutzengel herum? …Or just a little devil?... …Could survive our Species in this extra-stressing condition, which in the third decade of the March month 2020, seems to be unbearable? …Could one write, could one think, a book of all books of Sapiens, a verse of all verses of Sapiens, a formula of all formulas of Sapiens, an equation of all equations of Sapiens, in order to save Sapiens, or at least to alleviate its ordeal?... …Since Mid–December 2019, a strange and dangerous epidemic outbreak of an infectious virus, a viral disease, originating in Far East China, within Wuhan province, having at North the Nanjing city, at East is Hangzhou, at south is Changsha, and at West is Chongging, is ravaged the world, by sweeping over countries and continents, reaching its peak of mortality in Italy and Spain… The whole of Sapiens is haunted by this virus- phantom, by this Nano-metric-haunt, which can provoke serious diseases in human, some of them with lethal ending, through aggravated respiratory weaknesses, both in upper and down of respiratory system, called SARS – Severe Acute Respiratory Syndrome, with the particularity of Middle East area, called MERS, (Middle East) Severe Acute Respiratory System… The measures of closing businesses, schools, universities, museum, expositions, sport – events, including even the Olympic Games in July this year in Japan, then industry of tourism through airports and agreements places, then congresses and symposiums, including those of medical ones, with harsh boundaries controls between states, or between regions of the same countries, here are a somber development of this viral disease, called in scientific terms, COVID – 19, or by other as SARS – COVID 2! All of a sudden, billions and billions of Euro and Dollars have been pushed in all forms of medical precautionary of anti – viral measures, in hospitals, clinics, researching of new drugs or an efficient vaccine in this battlefield of all, called by myself as SAPIENS, against CORONA VIRUS! It is reported that some drugs, already used for other diseases, could have some positive actions for the treatment of this overspreading illness. Among millions and millions of doctors and assistants, of researcher and clinicians, throughout the world, there is also a theoretical searcher and researcher in this area, particularly in THEORETICAL MEDICINE, in recombining MEDICINE with PHILOSOPHY, as PHILOSOPHICAL MEDICINE, who is just… myself! It is noted that my previous two books regarding this dramatic topics, SAPIENTOLOGY & CORONA VIRUS and CORONA IS SAPIENS, are already published on line through Amazon – KDP, waiting also in days, their publishing on Google / Play /Book! Now, around of 25 March, 2020, is to hope the on line publishing of the third book about Corona virus, called SAPIENTOCOVID – 2020! Therefore, let’s try it; let’s encourage this kind of behavior in publishing books about this world wide plague, the sad dominance in our virus plague time of CORONA VIRUS, through these sets of On Lines books, of booklets and bookishes, all relating this pandemic infectious of worldwide disease… Sapientologist of Theoretical Virusology