Antimicrobial resistance (AMR) is a global public health threat. The menace of antimicrobial resistance is present across health, animal, agriculture, food, and environment sectors. It, therefore, requires an inter-disciplinary combat approach- the one health approach, envisaged by the FAO-UNEP-WHO-WOAH Quadripartite (Food and Agriculture Organization of the United Nations (FAO), the UN Environment Programme (UNEP), the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH). This comprehensive reference book provides a thorough understanding of antimicrobial resistance across different sectors. It presents deep insights and gives a global perspective on antimicrobial resistance for policymakers. The book offers essential and up-to-date information that enables researchers from multiple fields to design research on antimicrobial resistance. The book discusses molecular mechanisms and antibiotic resistance genes of significant antimicrobial-resistant pathogens, regulatory frameworks available worldwide, and mitigation strategies across the sectors, including probiotics, prebiotics, antimicrobial peptides, bacteriophages, phytochemical compounds, immunostimulants, vaccines, bacteriocins, etc. It compiles essays from leading experts in the field of antimicrobial resistance research. The book is meant for students and researchers in microbiology, medical microbiology, and public health. It is also helpful for clinicians and policymakers.

The first book to offer practical guidelines on the prudent andrational use of antimicrobials in animals. Drawing onmultidisciplinary expertise to offer independent scientific adviceon a controversial area that is crucial to both human health andanimal welfare. The earlier general chapters cover issues such ashuman health risks and the problems of resistance to antimicrobialdrugs. The later specific chapters are dedicated to particulargroups of animals. Has an emphasis on preserving the efficacy of antimicrobialdrugs that are clinically important in human medicine Covers both companion animals and food animals, includingaquaculture Suitable for veterinary practitioners working in small andlarge animal medicine, aquaculture and animal production, as wellas veterinary students, academics and researchers. It will also beof interest to those more generally involved in veterinary publichealth and antimicrobial resistance.

Handbook of Microbial Nanotechnology is a collection of the most recent scientific advancements in the fundamental application of microbial nanotechnology across various sectors. This comprehensive handbook highlights the vast subject areas of microbial nanotechnology and its potential applications in food, pharmacology, water, environmental remediation, etc. This book will serve as an excellent reference handbook for researchers and students in the food sciences, materials sciences, biotechnology, microbiology and in the pharmaceutical fields.Microbial nanotechnology is taking part in creating development and innovation in various sectors. Despite the participation of microbial nanotechnology in modern development, there are some hindrances. The lack of information, the possibility of adverse impacts on the environment, human health, safety and sustainability are still a challenge. This handbook addresses these challenges. Offers up-to-date, scientific information on the integration of microbiology and nanotechnology Explores how nanotechnology can improve the detection of trace chemical contaminants, viruses and bacteria in food and other industry applications Provides readers with a fundamental understanding of microbial nanotechnology and its challenges Includes real-time applications with case studies to illustrate how microbial nanotechnology influences modern sciences and technologies

With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.

Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

This document outlines the concept and content of the WHO people-centred approach to addressing antimicrobial resistance (AMR) in the human health sector. The proposed approach recognizes and aims to address the challenges and health system barriers people face when accessing health services to prevent, diagnose and treat (drug-resistant) infections. It puts people and their needs at the centre of the AMR response and guides policy-makers in taking programmatic and comprehensive actions to mitigate AMR in line with a proposed package of core interventions. These interventions are based on a review of four pillars and two foundational steps that are critical to overcome barriers faced by people and health systems in addressing AMR. The four pillars are: (1) prevention of infections; (2) access to essential health services; (3) timely, accurate diagnosis; and (4) appropriate, quality-assured treatment. The pillars are supported by the two foundational steps: effective governance, awareness and education; and strategic information through surveillance and research. Building and adding on to the objectives of the Global action plan on AMR, the 13 core interventions and accompanying priority actions are designed to address AMR in a programmatic manner that puts people, their needs and equitable access to health services at the centre of the AMR response in the community, in primary care, secondary and tertiary care, and at national and/or subnational level. The development of the people-centred core package of AMR interventions was based on a review of the evidence and multidisciplinary expert opinion, complemented with feedback from a global online consultation and WHO’s strategic and technical advisory group on antimicrobial resistance. As countries develop or revise their national action plans (NAPs) on AMR, the people-centred core package of interventions can support the design and prioritization of actions in the human health sector at the different levels of implementation and integrated with broader health system strengthening and pandemic preparedness and response plans.

The Global Action Plan on Antimicrobial Resistance (AMR) calls for making AMR a core component of professional education and training. In 2018, the World Health Organization (WHO) published Competency framework for health workers’ education and training on AMR to ensure that academic institutions and regulatory agencies provided pre-service and in-service training to equip health workers with the adequate competencies to address AMR. This was followed by Health workers’ training and education on AMR: curricula guide, which outlines the learning objectives and expected outcomes of pre-service training of health workers to improve curricula. The tool for assessing AMR curricula for medical education complements other WHO tools. Its aim is to identify gaps in curricula for medical education so that they can be remediated. This tool will allow a rapid review of curricula for training medical students in a national or university context to evaluate the robustness of their content for achieving the core competencies listed in the Competency Framework for Health Workers’ Education and Training on AMR. It can also assist in designing a strategy to enhance the AMR elements in curricula for medical education and to stimulate or facilitate periodic structured discussions on AMR and health worker competencies among the faculty of medical universities and other relevant stakeholders. A robust medical curriculum, which sufficiently includes AMR elements, will contribute to ensuring that future doctors have the necessary awareness and skills to address AMR in policy and practice.