This edited volume, Hormone Therapy and Replacement in Cancer and Aging-related Diseases, is a collection of reviewed and relevant research chapters, offering a comprehensive overview of recent developments in the field of hormone replacement therapy. The book comprises single chapters authored by various researchers and edited by experts active in the hormone replacement therapy research area. All chapters are complete in themselves but united under a common research study topic. This publication aims at providing a thorough overview of the latest research efforts by international authors on hormone replacement therapy, and opens new possible research paths for further novel developments.

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Ageing has become a great problem for many countries. Due to world-wide life prolongation the number of people over 6o years old has grown rapidly into a ten percent piece of the world population. The growing age of the world population raises many social, economical, and medical problems. The proportion of people in the economically active age groups to those who are over 65 is constantly decreasing. A major consequence of the increasing numbers of individuals in advanced age groups is increasing numbers of patients suffering from age-related diseases. The aim of this book is to present the basic data on human ageing as well as on age-related diseases.

Advances in Cosmetic Surgery includes the latest advances and breakthroughs in the field of cosmetic surgery from a multi-specialty perspective. Members of our distinguished editorial board, Gregory H. Branham, MD, Jeffrey S. Dover, MD, FRCPC, Heather J. Furnas, MD, Marissa MJ Tenenbaum, MD, and Allan E. Wulc, MD, FACS, have brought together the leading experts in the field to bring you this influential new publication. Articles in this volume include: The Latest in Cosmetic Medicine: Supplements, Hormones, and Evidence; Non-surgical Vaginal Treatments; Hand Rejuvenation; Non-Surgical Periorbital Rejuvenation; New Synergistic Tricks: Fillers + Neuromodulators + Technology = More Than the Sum; Tricks to Patient Retention for Maintenance Care; Submental Contouring: A Comparison of CoolSculpting, Kybella, and Liposuction; Treatments for the Aging Lip; Hair Loss in Men and Women: Medical and Surgical Therapies; Pain Control in the Age of an Opioid Epidemic; Facial Rejuvenation: Fat Transfer vs. Fillers; Subcutaneous Neck Plasma Skin Tightening; Update on the Treatment of the Skeletonized Upper Eyelid; Sculptural Aesthetic Surface Anatomy of the Face; Surgical Site Infections (SSIs) in Cosmetic Surgery; Microneedling (non-RF related); Defining the Brow Fat Pad: The Brassiere Suture; Plasma Resurfacing; Subcutaneous Body Skin Tightening; Update on the Treatment of Post-blepharoplasty Lower Eyelid Retraction; and PRP for Hair Growth. Be sure to order your copy of Volume 2 or subscribe today, so you don’t miss out on these important and timely updates in the field of cosmetic surgery!

How do some people avoid the slowing down, deteriorating, and weakening that plagues many of their peers decades earlier? Are they just lucky? Or do they know something the rest of us don’t? Is it possible to grow older without getting sicker? What if you could look and feel fifty through your eighties and nineties? Founder of the Institute for Aging Research at the Albert Einstein College of Medicine and one of the leading pioneers of longevity research, Dr. Nir Barzilai’s life’s work is tackling the challenges of aging to delay and prevent the onset of all age-related diseases including “the big four”: diabetes, cancer, heart disease, and Alzheimer’s. One of Dr. Barzilai’s most fascinating studies features volunteers that include 750 SuperAgers—individuals who maintain active lives well into their nineties and even beyond—and, more importantly, who reached that ripe old age never having experienced cardiovascular disease, cancer, diabetes, or cognitive decline. In Age Later, Dr. Barzilai reveals the secrets his team has unlocked about SuperAgers and the scientific discoveries that show we can mimic some of their natural resistance to the aging process. This eye-opening and inspirational book will help you think of aging not as a certainty, but as a phenomenon—like many other diseases and misfortunes—that can be targeted, improved, and even cured.

Cells, Aging, and Human Disease is the first book to explore aging all the way from genes to clinical application, analyzing the fundamental cellular changes which underlie human age-related disease. With over 4,000 references, this text explores both the fundamental processes of human aging and the tissue-by-tissue pathology, detailing both breaking research and current state-of-the-art clinical interventions in aging and age-related disease. Far from merely sharing a common onset late in the lifespan, age-related diseases are linked by fundamental common characteristics at the genetic and cellular levels. Emphasizing human cell mechanisms, the first section presents and analyzes our current knowledege of telomere biology and cell senescence. In superb academic detail, the text brings the reader up to date on telomere maintenance, telomerase dynamics, and current research on cell senescence--and the general model--cell senescence as the central component in human senescence and cancer. For each human malignancy, the chapter reviews and analyzes all available data on telomeres and telomerase, as well as summarizing current work on their clinical application in both diagnosis and cancer therapy. The second edition, oriented by organs and tissues, explores the actual physiological impact of cell senescence and aging on clinical disease. After a summary of the literature on early aging syndromes--the progerias--the text reviews aging diseases (Alzheimer's dementia, osteoarthritis, atherosclerosis, immune aging, presbyopia, sarcopenia, etc.) in the context of the tissues in which they occur. Each of the ten clinical chapters--skin, cardiovascular system, bone and joints, hematopoetic and immune systems, endocrine, CNS, renal, muscle, GI, and eyes--examines what we know of their pathology, the role of cell sensescence, and medical interventions, both current and potential.

Exercise and Sport Pharmacology is an essential book for teaching upper-level undergraduates or entry-level graduate students about how drugs can affect exercise and how exercise can affect the action of drugs. It leads students through the related pathology, exercise physiology, and drug action of many of today's chronically used medications, and discusses how drugs can affect exercise performance. This new second edition of the book is divided into four parts: Section I provides the basics of pharmacology, exercise physiology, autonomic pharmacology, and the stress response; Section II presents chapters on major cardiovascular and respiratory drug classes; Section III describes frequently prescribed medications for such common conditions as diabetes, depression, pain, fever, inflammation, and obesity; and Section IV includes discussions of nutritional supplements and commonly used drugs such as caffeine, nicotine, cannabis, and performance-enhancing drugs. The second edition offers many updates, enhances muscle cell physiology, includes the involvement of the gut microbiome, and each chapter has a new section on the effects of aging. In Sections II and III, chapters include an overview of the pathology that therapeutic drugs are designed to treat and how the drug works in the human body. In contrast to standard pharmacology texts, Exercise and Sport Pharmacology also includes the effect of exercise on the pathology of the condition and the effect of exercise on how the body responds to a drug. Each chapter has a section on whether the drugs under discussion have performance-enhancing potential. Section IV is concerned with self-medication and drugs or supplements taken without a prescription or with limited medical supervision. Throughout, figures and tables as well as data from experiments in exercise pharmacology help to illustrate and summarize content. Each chapter opens with an on-going case example to preview and apply chapter content. In the text, boldface terms indicate which concepts are contained in the book's Glossary. Chapters conclude with a Key Concepts Review and Review Questions.

As a group, baby boomers are heading rapidly into their "golden years," and there's little doubt that they won't go lightly. But is the process really irrevocable and irreversible? With more financial resources than any other demographic, and the knowledge gained simply by living, boomers are in the best position to at least delay the aging process. This practical guide offers a wealth of ways to do that. Dr. Beverly Potter, who has written numerous books on enhancing one's lifestyle, includes but goes beyond anti-aging and life extension. Youthfulness, she says, is characterized by vigor, flexibility, bounciness, good health, physical shapeliness, beauty, curiosity, and mental acuity — all of which can be achieved through the regimens the book describes. Potter takes a multifaceted approach, incorporating both current science and proven techniques into a program that stresses vitamins, nutrients, healthful foods, and supplements; activities and lifestyles; ways of thinking; sexual techniques; brain fitness training; and more.