As with any delicate machine, the human body can be profoundly affected by its supply of vital running materials. Thus, the tendency for the blood to clot excessively has the potential to cut off the oxygen supply to any organ of the body. In 1983, Dr Graham Hughes and his team in London described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the anti-phospholipid syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke. More important, it is treatable. This book provides the first in-depth description of the syndrome for patients.

In 1983 Graham Hughes described a syndrome in which the blood has a tendency to clot. Hughes syndrome is at the root of diverse conditions such as stroke, leg vein thrombosis and recurrent abortion. Hughes Syndrome addresses the complete range of features produced by this common disorder, which is also known as antiphospholipid syndrome. The condition can affect any organ, and is treated using commonly available drugs including low-dose aspirin and warfarin. This timely book fulfils the need for a cross-disciplinary clinical textbook and contains contributions from the leading international authorities. Hughes Syndrome should be read by anyone who might have a clinical or scientific interest in this condition: rheumatologists, haematologists, obstetricians and neurologists.

Along with AIDS, antiphospholipid syndrome was the major medical discovery of the late 20th century, so for many it is still deemed a ‘new’ disease. The discovery of ‘sticky blood’ (commonly known as antiphospholipid syndrome or ‘Hughes Syndrome’) came out of years of observation of patients who had developed lupus. Many specialists in the 1970s were interested in the neurological aspects of lupus, and Dr Hughes, among others, spent a number of years studying the mechanisms of brain inflammation. In the mid 1970s, Hughes observed a number of young women with a form of viral paralysis, where interestingly many of them carried an antibody in their blood actually directed against ‘phospholipid’ – one of the components of brain and spinal cord. It quickly became apparent that individuals who had "anti-phospholipid antibodies" suffered from a tendency not only to develop brain and spinal cord symptoms, but also a tendency to develop both vein and artery thrombosis. As investigation continued it became apparent that these symptoms were not just confined to lupus patients, but occurred in others too, specifically those with severe migraines, with repeated strokes, with memory loss, and in women with recurrent miscarriage.

Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable. Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training.

Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: * responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin) * responsible for 1 in 5 young (under 45) strokes * a major cause of early heart attacks * responsible for 1 in 5 deep vein thromboses * an important cause of migraine. Hughes Syndrome: Highways and Byways is a valuable resource for professionals with an interest in the subject, as well as general practitioners and patients.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.The ULTIMATE reference about syndromes to have on hand to facilitate rapid recognition and perioperative implications --- in full colorSyndromes: Rapid Recognition and Perioperative Implications, Second Edition, is the ultimate reference for anesthesiologists, surgeons, internists, pediatricians, emergency physicians and nurses caring for patients affected with special operative needs and acute medical care. This updated book provides a complete A-to-Z encyclopedic clinical presentation of more than 2,200 syndromes. Extensive cross-referencing of international synonyms, classifications, and other conditions to be considered in the differential diagnosis further expands coverage to more than 5,000 entries. It is the most comprehensive reference on the subject. Syndromes: Rapid Recognition and Perioperative Implications, Second Edition, is enhanced by 200 high-quality photographs, in addition to tables, classifications and clinical management considerations. The addition of color tabs, a new feature, improve consultation and speed information retrieval. Each syndrome, listed in alphabetical order, is described as follows:•“At a glance” description•Synonyms•Incidence•Genetic Inheritance•Pathophysiology•Diagnosis•Clinical Aspects•Precautions Before Anesthesia•Anesthetic Considerations•Pharmacological Implications•Other conditions to be considered•ReferencesHealth care providers, fellows and residents in training will find this textbook to be an essential reference to improve patient care in this highly demanding medical and surgical environment.