This book provides a clearly structured introduction to hydrogen biology and medicine. Hydrogen is the one of the most abundant elements in the universe and has the simplest structure. In 2007, Japanese researchers found that the selective oxidation of hydrogen has a therapeutic effect on various diseases and injuries, sparking widespread interest in the biomedical field. In recent years, hundreds of peer-reviewed papers have been published internationally reporting the positive effects of hydrogen on many human diseases, including strokes, diabetes, Parkinson's disease, Alzheimer's disease and sepsis. The authors provide readers with a comprehensive overview of this subject, from its physical and chemical properties to its biological effects, as well as the problems and obstacles that exist.

This book provides a comprehensive account of the current status of molecular hydrogen medicine, a young field that emerged with the discovery that inhalation of hydrogen gas leads to the elimination of harmful reactive oxygen species in rats. Various physiologic effects have since been demonstrated, and possible medical applications identified. Numerous clinical projects have now been undertaken, yielding startling results. Despite this, molecular hydrogen medicine remains underappreciated among the medical community at large. The author aims to rectify this situation by fairly but critically evaluating the potential clinical benefits based on the latest scientific research. In addition, the observed physiological effects of hydrogen gas are considered within the broad context of the evolution of life on earth, offering new perspectives and helping to place molecular hydrogen medicine legitimately within the framework of life sciences. Written in an accessible manner, the book will be of value to students, researchers, clinicians, and the general public.

This book will explore hydrogen gas, hydrogen water, oxygen (O2), and carbon dioxide (CO2). Combining these gases will usher in a new age of medicine where the impossible becomes possible. Hydrogen is serious medicine, and so is oxygen and carbon dioxide. All three gases are nutritional and are of enormous help to people with pain, disease, and cancer. Hydrogen allows the body to function and breathe under stress. And it allows for quicker healing and recovery than when oxygen alone is used. The sicker a person is, the more they will experience the benefits of hydrogen. Hydrogen can be flooded into the body to put out the worst flames of inflammation and oxidative stress. The longer one wants to live, the more one supplements with these primary gases. The most powerful healing/medical/anti-aging device in the world is a hydrogen oxygen inhaler.

This book is designed to convey as much information as possible in a concise and simple way to make it suitable for students, researchers and clinical medical physicists. Better meanings, codes and examples are included. Most of the basics are also covered for easy reference along with a glossary of objective-type questions. Upon completion of this textbook, the readers will gather knowledge about the physics, chemistry and biology of the human body towards cancer treatment using radiation.

Introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning, using real-world biological and medical examples.

Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an insightful and useful forum to assist with the understanding of the relevance of hydrogen peroxide generation and how this is managed in human biology. The target audience would be those who currently have an interest in the generation of ROS, but who do not have expertise in chemistry, as well as those experts in the chemistry of oxidative stress, but without detailed understanding of the biologically relevant setting. We would aim to bridge the gap in understanding between chemistry and biology.

The most promising natural substance in our body is NADH, the biological form of hydrogen. It reacts with the oxygen present in every living cell, producing energy and water. The more NADH a cell has available, the more energy it can produce, the better it functions, and the longer the cell-and the entire organism-lives. ATP is the life energy for every cell. If less NADH is present in the cell, less ATP is synthesized. Certain diseases, particularly Alzheimers̲ dementia and Parkinsons̲ disease, are caused by impairment in ATP production. We can increase the ATP content in a cell by supplementing with NADH. Men and women are better protected against health problems the more NADH they have available in their bodies. NADH has numerous functions in the body: it repairs DNA and revitalizes damaged cells, acts as a potent antioxidant, lowers cholesterol and high blood pressure, and boosts the immune system. NADH has proven effective for the following conditions: -Parkinsons̲ disease Depression -Chronic fatigue syndrome Cancer -Alzheimers̲ dementia Strokes Diabetes NADH has therapeutic uses for menopause, obesity, skin problems, jet lag, and sexual dysfunction. Athletes have also found it useful for boosting athletic performance, and it may even help you live a longer and healthier life. Though NADH is present in foods, we take up only marginal amounts from our daily diet. Fortunately, a safe and effective NADH supplement is now available. Written by the developer of oral NADH, this book will inform readers about NADH, its functions that are essential for life and its multiple healthful effects in the human body.

These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant. - Continues the legacy of this premier serial with quality chapters on hydrogen sulfide research authored by leaders in the field - Covers conventional and new hydrogen sulfide detection methods - Covers the pharmacological activity of hydrogen sulfide donors - Contains chapters on important topics on hydrogen sulfide modulation of cell signaling and transcriptional pathways, and the role of hydrogen sulfide in the cardiovascular and nervous systems and in inflammation

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This is the third of three volumes on hydrogen peroxide and cell signaling, and includes chapters on such topics as the biological chemistry of hydrogen peroxide, reactive oxygen species in the activation of MAP kinases, and investigating the role of reactive oxygen species in regulating autophagy. - Continues the legacy of this premier serial with quality chapters authored by leaders in the field - Covers hydrogen peroxide and cell signaling - Contains chapters on such topics as the biological chemistry of hydrogen peroxide, reactive oxygen species in the activation of MAP kinases, and investigating the role of reactive oxygen species in regulating autophagy

Oxygen, Nitrogen and Sulfur Species in Post-harvest Physiology of Horticultural Crops, a volume in the Plant Gasotransmitter series, analyzes the latest advances in post-harvest physiology. The book presents metabolic cascades and highlights the role of gasotransmitters as intercellular regulators of metabolic processes. Post-harvest physiology differs between climacteric and non-climacteric fruits and vegetables, as well as for fresh-cut flowers and non-food plants. Initial chapters review the cascades, intercellular pathways and messenger molecules that drive ripeness and longevity, presenting the chemistry behind key pathways. The books also takes a deep dive into core gasotransmitters, describing the data behind known properties, chemistry and physiological roles. Applications for prolonging shelf-life via the control of post-harvest fungi, bacteria and omics approaches are reviewed in detail, offering readers guidance on how to put gasotransmitters research into practice. This is an essential resource for students, researchers and agronomists interested in plant physiology, biochemistry and plant hormones. - Describes the use and application of oxygen, nitrogen and sulfur species towards the prolonging of post-harvest shelf-life in agricultural products - Explores eco-friendly alternatives to hazardous chemical compounds used to preserve fruits - Presents metabolic cascades and evaluates the crosstalk and interaction of gasotransmitters within these cascades