This book provides the reader with a detailed update on the use of stereotactic radiosurgery (SRS) in patients with lesions of the brain and other parts of the body. The aim is not simply to explain the application of SRS and document its value with reference to the author's own clinical experiences and other published evidence, but also to contextualize the technology within a new strategic concept of cancer care. When embedded within an appropriate conceptual framework, technology becomes pivotal in changing therapeutic strategies. A new paradigm that is increasingly impacting on clinical practice is the oligometastatic state, on the basis that long-term survival might be achieved in patients with a low volume and number of metastatic lesions. This book accordingly addresses the value of SRS in patients with oligometastases of solid tumors to the brain, lung, spine, and liver. In addition, it examines the use of SRS in patients with diverse brain lesions, early-stage stage lung cancer, liver cancer, and early-stage prostate cancer. Readers will be persuaded that SRS, using cutting-edge imaging technologies to deliver precisely targeted radiation therapy, represents an exciting non-invasive procedure that holds great promise for the present and the future of cancer care.

Following recent developments in hypofractionated stereotactic radiation therapy (SRT) for brain and spine tumors, this new edition offers a fully updated and comprehensive "how-to" guidance on hypofractionated SRT for brain and spine metastases, glioma, benign tumors, and other tumor types. Presenting the state of the art of the technology and practice, this book: • Discusses the pros and cons of hypofractionated SRT compared to single-fraction radiosurgery, providing a deeper understanding of radiosurgery and radiobiology • Explains the toxicity and adverse effects of hypofractionated SRT including the dosage of 24 Gy in two spine SBRT fractionation schemes, aiding practitioners in communicating the risks and benefits of treatment and in obtaining consent from their patients • Outlines the current standards for safe practice, including checklists for implementation • Explores new technologies for brain and spine tumors including LITT, MR-guided focused ultrasound, and Zap technology, with chapters authored by well-recognized experts in the radiation, oncology, and neurosurgery communities; this book delivers a level of technological and clinical detail not available in journal papers This book is suitable for radiation oncologists, neurosurgeons, and medical physicists who specialize in brain and/or spine radiosurgery or want to start a program and need a comprehensive reference with key checklists for practice.

This book provides detailed, state-of-the-art information and guidelines on the latest developments, innovations, and clinical procedures in image-guided and adaptive radiation therapy. The first section discusses key methodological and technological issues in image-guided and adaptive radiation therapy, including use of implanted fiducial markers, management of respiratory motion, image-guided stereotactic radiosurgery and stereotactic body radiation therapy, three-dimensional conformal brachytherapy, target definition and localization, and PET/CT and biologically conformal radiation therapy. The second section provides practical clinical information on image-guided adaptive radiation therapy for cancers at all common anatomic sites and for pediatric cancers. The third section offers practical guidelines for establishing an effective image-guided adaptive radiation therapy program.

Image-Guided Radiation Therapy presents key image-guided radiation treatment (IGRT) technologies for external beam radiotherapy. The book explores the decades-long technological developments that have occurred in the realm of image-guided conformal, customized radiation treatment. Expert authors, all of whom have actively participated in the develo

Responding to the growing demand for minimally invasive procedures, this book provides a comprehensive overview of the current technological advances in image-guided surgery. It blends the expertise of both engineers and physicians, offering the latest findings and applications. Detailed color images guide readers through the latest techniques, including cranial, orthopedic, prostrate, and endovascular interventions.

Lung cancer is the leading cause of cancer death in the United States, but IGRT (image guided radiation therapy) offers the possibility of more aggressive and enhanced treatments. The only available source on the subject that emphasizes new imaging techniques, and provides step-by-step treatment guidelines for lung cancer, this source helps clinici

Image Guided Radiation Therapy (IGRT) is a true revolution in the field of radiation oncology. IGRT provides the unprecedented means of conforming does to the shape of the target tissues in 3-dimensions reducing the risk of complications thereby improving the quality of life of irradiated patients. Moreover, IGRT provides the means to deliver higher than conventional doses thus improving the chance of cure in these patients. Despite its established benefits, several barriers exist to the widespread clinical implementation of IGRT. In the past, great concerns existed regarding the large capital outlay needed for both software and hardware. This barrier is less relevant today given the increased reimbursements possible with IGRT. Today, the most significant barrier is education. IGRT is a fundamentally new approach to both treatment planning and delivery. Adoption of the IGRT approach entails new ways of thinking in regard to patient selection, treatment planning and quality assurance measures. Unfortunately, apart from a few University-based short courses, limited resources are available for the physician and physicist interested in learning IGRT.

Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.

Image-Guided Neurosurgery provides readers with an update on the revolutionary improvements in imaging and visualization relating to neurosurgery. From the development of the pneumoencephalogram, to the operating microscope, to cross sectional imaging with CT and later MRI, to stereotaxy and neuronavigation, the ability to visualize the pathology and surrounding neural structures has been the driving factor leading surgical innovation and improved outcomes. The book provides a comprehensive reference on the application of contemporary imaging technologies used in neurosurgery. Specific techniques discussed include brain biopsies, brain tumor resection, deep brain stimulation, and more. The book is ideal for neurosurgeons, interventional radiologists, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering. - A comprehensive reference on image-guided neurosurgery - Includes coverage of neuronavigation in cranial surgery and advanced imaging, including functional imaging, adoption of intra-operative MRI and emerging technologies - Covers all image-guided neurosurgery tools, including robotic surgical devices - Ideal reference for topics relating to neurosurgery, imaging, stereotaxis, radiosurgery, radiology, epilepsy, MRI, the use of medical robotics, lasers, and more

Surface Guided Radiation Therapy provides a comprehensive overview of optical surface image guidance systems for radiation therapy. It serves as an introductory teaching resource for students and trainees, and a valuable reference for medical physicists, physicians, radiation therapists, and administrators who wish to incorporate surface guided radiation therapy (SGRT) into their clinical practice. This is the first book dedicated to the principles and practice of SGRT, featuring: Chapters authored by an internationally represented list of physicists, radiation oncologists and therapists, edited by pioneers and experts in SGRT Covering the evolution of localization systems and their role in quality and safety, current SGRT systems, practical guides to commissioning and quality assurance, clinical applications by anatomic site, and emerging topics including skin mark-less setups. Several dedicated chapters on SGRT for intracranial radiosurgery and breast, covering technical aspects, risk assessment and outcomes. Jeremy Hoisak, PhD, DABR is an Assistant Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Hoisak’s clinical expertise includes radiosurgery and respiratory motion management. Adam Paxton, PhD, DABR is an Assistant Professor in the Department of Radiation Oncology at the University of Utah. Dr. Paxton’s clinical expertise includes patient safety, motion management, radiosurgery, and proton therapy. Benjamin Waghorn, PhD, DABR is the Director of Clinical Physics at Vision RT. Dr. Waghorn’s research interests include intensity modulated radiation therapy, motion management, and surface image guidance systems. Todd Pawlicki, PhD, DABR, FAAPM, FASTRO, is Professor and Vice-Chair for Medical Physics in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Pawlicki has published extensively on quality and safety in radiation therapy. He has served on the Board of Directors for the American Society for Radiology Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM).