Mechanisms and Manifestations of Obesity in Lung Disease is a complete resource on the epidemiology and molecular mechanisms related to obesity and lung disease. Obesity has not simply changed the epidemiology of pulmonary disease, it has had a profound impact on the pathophysiology of common pulmonary diseases. As the obesity epidemic has taken hold throughout the developed world, scientists and clinicians are now challenged with identifying the mechanisms by which obesity alters lung health and the pathogenesis of lung diseases. This book is an important new resource for both clinicians and scientists dealing with these new health problems in pulmonary medicine. Presents an all-in-one resource that describes the impact of obesity on the development and severity of lung disease Details the molecular and immunologic mechanisms by which obesity impacts the pathogenesis and outcomes of lung disease Includes contributions from authors who are internationally recognized as leaders in the area of obesity and lung disease

This new edition provides a fully updated guide to obesity's relation to lung disease. Over forty percent of the U.S. population is obese, and obesity is increasing in much of the world. Obesity has a major impact on health conditions such as diabetes and cardiovascular disease. The effects of obesity on lung disease have drawn increasing attention in recent years. Furthermore, the COVID pandemic has dramatically illustrated how obesity affects respiratory disease, constitutes a major risk factor for COVID-19, and presents challenges to pulmonary care in the ICU. Obesity changes physiology, immune and metabolic function, and is associated with changes in diet and the microbiome, all of which combine to have a major impact on the pathogenesis of respiratory diseases. Obesity is thus a risk factor for many respiratory diseases such as asthma, pulmonary hypertension, thromboembolic disease, obstructive sleep apnea and ARDS. Obesity also complicates the management of many other respiratory diseases and conditions such as COPD, thromboembolic disease, and the care of the critically ill patient. The objectives of this book are three-fold: To review how physiological, immune and metabolic factors might contribute to lung disease. To discuss the impact of obesity on common lung diseases To outline important considerations in the management of critically ill obese patients. There have been major advances in our understanding of the relationship between obesity and lung disease since the first edition in 2013, in addition to the major lessons learned about the importance of obesity during the COVID-19 pandemic. This has led to the addition of eight new chapters on topics such as, the microbiome, lung transplant, and COVID-19 in the ICU. This is an ideal guide for all clinicians taking care of patients with pulmonary and critical care diseases, as well as basic and translational scientists interested in how obesity affects respiratory health.

Obesity and its associated comorbidities (e.g. type II diabetes and cardiovascular disease) represent a serious challenge for healthcare systems worldwide. Obesity is a chronic disease, characterized by excessive adipose tissue mass, resulting from an imbalance between energy intake and expenditure, with growing relevance in an increasingly sedentary society. Obesity is multifactorial, where alterations in the physiology of gastrointestinal hormones, playing a key role in the interplay between the gastrointestinal system and the brain, and in the gut microbiota, contribute to the development of this disorder.

A companion book to the best-selling Immunity Food Fix, The Immunity Food Fix Cookbook delivers 75 delicious superfood recipes that support your body’s natural defenses. Studies have shown that nutrition impacts immunity and disease development. What you put on your plate can either heal you or hurt you. The Immunity Food FixCookbook gives you superfood recipes that naturally support robust immunity. Aside from being accessible and delicious, food is less expensive than medication and free of side effects and, unlike supplements, has the most complete form of the nutrient. While adding the top immune-supportive foods to your diet individually can provide benefit, recipes and meals give you the opportunity to combine different immune superfoods for maximum nutrient density, absorption, and flavor appeal. Recipes are organized around the 5 key pillars of immune support: reversing inflammation, detoxification, antioxidants, digestion and microbiome health, and hormone balance and signaling. Supporting your immunity has never been so appealing. Inside, you’ll find delicious whole food recipes, including gluten-free, dairy-free, and grain options. Enjoy recipes such as: Soothing & Calming Licorice Lavender Latte Sprouted Quinoa Porridge with Raspberries & Hazelnut Butter Pumpkin Cardamom Oats with Coconut Butter & Orange Zest Egg Muffins with Butternut & Sunflower Seed Pesto Chicken Radicchio Salad with Apple, Celery & Cashews with Apricot Dressing Roasted Butternut & Avocado Salad with Lemon & Kalamata Olives Tuna, Chickpea & Arugula Salad with Lemon & Tarragon Vinaigrette Tomato Peach Fruit Salsa with Black Beans & Lime Cantaloupe & Smoked Salmon Caprese with Lemon Mint Sauce Thai-Spiced Coconut Lentil Soup Savory Mushroom & Chestnut Soup with Thyme Green Tea Rice Bowls with Miso Glazed Salmon Lemony Shrimp Chickpea Pasta with Spinach & Walnuts Fig & Apricot Almond Balls with Pistachio & Cacao Nibs Passion Fruit Panna Cotta Tahini Chocolate Chip Cookies Immune response underpins everything from chronic health conditions, such as diabetes and heart disease, to warding off the common cold to how well one ages. So start boosting your immunity at the very next meal with The Immunity Food Fix Cookbook!

Human-Gut Microbiome: Establishment and Interactions gives an overview of microbiome establishments in humans and basic technologies used to decipher the structure and function of gut microbiome. Other sections focus on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more. The book provides the basics, as well as mechanistic knowledge underpinning the structural and functional understanding of the microbiome. With the advancement in omics technologies, as well as the development of bioinformatic tools, much research has been undertaken to decipher the microbiomes of different hosts. This research is generating valuable insights into micro-ecological niches and their impact on humans, hence this new release covers these new insights. The book will be a valuable resource for scientists, researchers, postgraduate and graduate students who are interested in understanding the impact and importance of the omics approach to humans and their microbiomes. - Provides an overview of the recent developments in meta-omics technologies - Serves as a unique reference for healthcare professionals, pursuing research on gut homeostasis, and functional foods, as well as nutritional dietary management - Focuses on the application of microbiomics in different disease manifestations, such as obesity, diabetes, and more

The collection of essays reviews, explores, and reports state-of-the-art autoimmunity issues with a cause and effect relationship. It provides a comprehensive presentation of immunity and autoimmunity and their connection to related diseases, current trends, data and possible future developments in health sciences. As such, it represents a unique resource for medical educators, medical practitioners and academics.

Human Microbiome Drug Targets: Modern Approaches in Disease Management presents fundamental information on the human microbiome, looking into the relationship between the microbiome and how it changes with specific diseases. Delving into the multifaceted roles of the microbiome in health and disease, the book's chapters discuss the role of the human microbiome in the pathophysiologic understanding of relevant diseases or disorders and their management. As changes in the human microbiome can provide clues to the probable cause and effect of diseases or disorders, as well as the impacts of therapy or intervention, this book is a welcomed addition to the existing research. Explaining how a better understanding of the microbiome and its impact on health and disease can pave the way for future discoveries leading to better health outcomes, this book will be of interest to drug developers, medicinal chemists, microbiologists, infectious disease specialists, biochemists, and students. - Provides readers with background information on the human microbiome, its evolution, and current understanding - Includes chapters dedicated to the importance of the human microbiome as "drugs" and as drug targets - Serves as a guide to drug developers working in pharma, biotech, and academia, bringing together the latest research on the topic

Obesity is one of the relevant public health concerns and it is evident that body weight control is achieved through highly integrated physiological interactions like nutrient selection. Presenting an account of the roles of specific peptides in energy balance, this title provides an understanding of the patho-physiology of energy balance.