The book provides an excellent introduction to industrial biotechnology, addressing the applications of biomolecules and living systems in industrial manufacturing of various products. Each part of the book is devoted to a certain biotech sector, such as biofuels, food, chemicals, pharmaceuticals and materials. The book also covers the environmental aspects of industrial biotechnology and the principles of bio-based economy.

The latest volume in the Advanced Biotechnology series provides an overview of the main product classes and platform chemicals produced by biotechnological processes today, with applications in the food, healthcare and fine chemical industries. Alongside the production of drugs and flavors as well as amino acids, bio-based monomers and polymers and biofuels, basic insights are also given as to the biotechnological processes yielding such products and how large-scale production may be enabled and improved. Of interest to biotechnologists, bio and chemical engineers, as well as those working in the biotechnological, chemical, and food industries.

Industrial biotechnology has become the primary driver of sustainable technologies, advancing green chemistry, reuse technology, and the bio-based economy. In fact, utilizing enzyme technology and/or fermentation processes, a broad variety of chemical compounds, including fine and bulk chemicals, may now be produced from non-fossil, renewable resources including sugars and cellulosic, plant, and animal-derived oils. Industrial biotechnology will spread quickly across the chemical, agricultural, food, and environmental sectors as a result of the ecological and technical advantages it offers. The goal of this book is to provide a complete overview of industrial biotechnology, including its enabling technologies and the many fields in which it has found application. This book discusses fundamental and enabling technologies in microbial biotechnology, including genomics, bioinformatics, metabolic engineering, modelling, directed evolution of the enzymes, fermentation technology, biocatalysis, systems biology, nanotechnology, and downstream processing. This book covers main aspects in industrial biotechnology, including the production of microorganisms for commercial purposes, the use of thermophile bacteria in industrial microbiology, the use of microbes in waste water treatment and agriculture, and the creation of microorganism-derived products while comprehending the basic principles of microbial development, such as the phases of fermentation processes. The book goes on to examine enzyme reactors and associated technologies, enzyme genetic engineering, enzyme protein engineering, and the generation of biological fuel.

This important new book covers recent advancements, innovations, and technologies in industrial biotechnology, specifically addressing the application of various biomolecules in industrial production and in cleaning and environmental remediation sectors. The goal of industrial biotechnology is to develop new techniques and technologies to transform renewable raw materials into chemicals, materials, and fuels by the substitution of fossil fuels. With the increase in the world’s population and the resultant growing energy demand, the need for more energy can be successfully met with the advancements in industrial biotechnology. Currently across the globe significant research has been undertaken in the production of cleaner fuels, materials, and semi-synthetic chemicals, with environmental benefits. Developing countries have huge agricultural resources that could be utilized for production of value-added byproducts for the sustainable development of bio-based economy. The book opens with the chapter on the production of exopolysaccharides from halophilic microorganisms, a polymer that is normally very useful in various production sectors of the food, pharmaceutical, and petroleum industries. The book goes on to cover: The production of antimicrobial compounds from alkaliphilic bacteria Thermophilic actinomycetes Food, agro, and pharmaceutical potential and biotechnological applications of biosurfactants, halophiles, cyclodextrin glycosyl transferease, fungal chitinase, proteases, yeasts and yeast products Also covered in the book are the environmental aspects of industrial biotechnology such as the genetic enhancement for biofuel production, the production of biodegradable thermoplastics, advancements in the synthesis of bio-oil, ecofriendly treatment of agro-based lignocelluloses, and anaerobic bio reactors for hydrocarbon remediation. The international roster of chapter authors have been chosen for their renowned expertise and contribution to the various fields of industrial biotechnology. This book is suitable to chemists, biotechnologists from research institutes, academia, and students as well as for industry professionals

DOWNSTREAM INDUSTRIAL BIOTECHNOLOGY An affordable, easily accessible desk reference on biomanufacturing, focused on downstream recovery and purification Advances in the fundamental knowledge surrounding biotechnology, novel materials, and advanced engineering approaches continue to be translated into bioprocesses that bring new products to market at a significantly faster pace than most other industries. Industrial scale biotechnology and new manufacturing methods are revolutionizing medicine, environmental monitoring and remediation, consumer products, food production, agriculture, and forestry, and continue to be a major area of research. The downstream stage in industrial biotechnology refers to recovery, isolation, and purification of the microbial products from cell debris, processing medium and contaminating biomolecules from the upstream process into a finished product such as biopharmaceuticals and vaccines. Downstream process design has the greatest impact on overall biomanufacturing cost because not only does the biochemistry of different products ( e.g., peptides, proteins, hormones, antibiotics, and complex antigens) dictate different methods for the isolation and purification of these products, but contaminating byproducts can also reduce overall process yield, and may have serious consequences on clinical safety and efficacy. Therefore downstream separation scientists and engineers are continually seeking to eliminate, or combine, unit operations to minimize the number of process steps in order to maximize product recovery at a specified concentration and purity. Based on Wiley’s Encyclopedia of Industrial Biotechnology: Bioprocess, Bioseparation, and Cell Technology, this volume features fifty articles that provide information on down- stream recovery of cells and protein capture; process development and facility design; equipment; PAT in downstream processes; downstream cGMP operations; and regulatory compliance. It covers: Cell wall disruption and lysis Cell recovery by centrifugation and filtration Large-scale protein chromatography Scale down of biopharmaceutical purification operations Lipopolysaccharide removal Porous media in biotechnology Equipment used in industrial protein purification Affinity chromatography Antibody purification, monoclonal and polyclonal Protein aggregation, precipitation and crystallization Freeze-drying of biopharmaceuticals Biopharmaceutical facility design and validation Pharmaceutical bioburden testing Regulatory requirements Ideal for graduate and advanced undergraduate courses on biomanufacturing, biochemical engineering, biopharmaceutical facility design, biochemistry, industrial microbiology, gene expression technology, and cell culture technology, Downstream Industrial Biotechnology is also a highly recommended resource for industry professionals and libraries.

Issues in Animal, Marine, Food, and Industrial Biotechnology: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Marine Biotechnology. The editors have built Issues in Animal, Marine, Food, and Industrial Biotechnology: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Marine Biotechnology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Animal, Marine, Food, and Industrial Biotechnology: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Animal, Marine, Food, and Industrial Biotechnology: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Animal, Marine, Food, and Industrial Biotechnology. The editors have built Issues in Animal, Marine, Food, and Industrial Biotechnology: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Animal, Marine, Food, and Industrial Biotechnology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Animal, Marine, Food, and Industrial Biotechnology: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Protein engineering has proved to be one of the more fruitful technological approaches in biotechnology, being both very powerful and able to generate valuable intellectual property. This book aims to present examples in which the application of protein engineering has successfully solved problems arising in industrial biotechnology. There is a sec