In everyday parlance, "inhibition" suggests repression, tight control, the opposite of freedom. In medicine and psychotherapy the term is commonplace, its definition understood. Relating how inhibition—the word and the concept—became a bridge between society at large and the natural sciences of mind and brain, Smith constructs an engagingly original history of our view of ourselves. Not until the late nineteenth century did the term "inhibition" become common in English, connoting the dependency of reason and of civilization itself on the repression of "the beast within." This usage followed a century of Enlightenment thought about human nature and the nature of the human mind. Smith traces theories of inhibitory control from the moralistic psychologies of the early nineteenth century to the famous twentieth-century schools of Sherrington, Pavlov, and Freud. He finds that the meanings of "inhibition" cross disciplinary boundaries and outline the growth of our belief in the self-regulated person.

Learn the synthesis, characterization, scaling mechanisms, and applications of green antiscalants to be utilized in modern industrial platforms Scale formation, or mineral accumulation on the interior surfaces of water lines and containers, is a serious and expensive hazard in numerous industries. The prevention and elimination of scales has long been a major project demanding the production of antiscalant materials; increasing awareness of the toxicity of traditional antiscalants, however, and rising environmental consciousness has increased demand for green antiscalants. It's an exciting time for new chemists and chemical engineers to get involved in this growing field. Industrial Scale Inhibition provides a comprehensive introduction to existing and ongoing developments in green antiscalants. With coverage of synthesis, characterization, and many more subjects, it promises to make a serious contribution to environmentally conscious industry. The range of environmentally alternatives to traditional toxic antiscalants is explored and analyzed in this crucial volume. Industrial Scale Inhibition readers will also find: Detailed coverage of both synthetic and natural antiscalants Up-to-date reference material including pertinent websites and connections to the latest research Analysis of plant extracts, natural polymers, oleochemicals, and many more Industrial Scale Inhibition is a useful reference for chemists and chemical engineers working in research and development and academia, as well as high-level researchers working in the fields of material science and engineering, nanotechnology, energy, environment, colloid sciences, among others.

Enzyme Inhibition and Bioapplications is a concise book on applied methods of enzymes used in drug testing. The present volume will serve the purpose of applied drug evaluation methods in research projects, as well as relatively experienced enzyme scientists who might wish to develop their experiments further. Chapters are arranged in the order of basic concepts of enzyme inhibition and physiological basis of cytochromes followed by new concepts of applied drug therapy; reliability analysis; and new enzyme applications from mechanistic point of view.

Behavioral inhibition, often displayed as shyness in children and avoidance in animals, can be observed in the earliest stages of infancy. Recent research indicates that in extreme cases the tendency to either approach or withdraw from uncertain events continues through late childhood and is supported by specific biological mechanisms, suggesting a genetic basis. To effectively study behavioral inhibition, researchers are departing from the essentially experiential and descriptive techniques of traditional psychology and turning to a multidisciplinary approach that integrates psychology, psychiatry, epidemiology, genetics, and ethology. Perspectives in Behavioral Inhibition brings together the most current research of leading scholars in the various disciplines involved.

The use of social sterotypes as a basis for judgments and behavioral decisions has been a major focus of social psychological theory and research since the field began. Although motivational and cognitive influences on stereotyping have been considered, these two general types of influence have rarely been conceptually integrated within a common theoretical framework. Nevertheless, almost every area of theoretical and empirical concern in social cognition--areas such as the interpretation of new information, memory and retrieval processes, impression formation, the use of heuristic vs. analytic processing strategies, the role of affect in information processing, and self-esteem maintenance--has implications for this important social phenomenon. This volume's target article brings together the research of Galen Bodenhausen, Neil Macrae, and others within a theoretical framework that accounts for the processes that underlie both the activation of stereotypes and attempts to suppress their influence. They consider several stages of processing, including: *the categorization of a stimulus person; *the influence of this categorization on the interpretation of information about the stimulus person; and *the social judgments and behavioral decisions that are ultimately made. The stereotype activation and suppression mechanisms that the target article authors consider operate at all of these stages. Their conceptualization provides a framework within which the interrelatedness of processing at these stages can be understood. The 11th in the series, this volume includes companion articles that help to refine and extend the target article's conceptualization and make important theoretical contributions in their own right. They are written by prominent researchers in cognitive and social psychology, many of whom are active contributors to research and theory on stereotyping. They address the following topics: * the role of power and control in stereotype-based information processing; * the influence of prejudice; * self-regulatory processes; * social categorization; * the correction processes that result from perceptions of bias; and * the conceptualization of stereotypes themselves.

In this book, academic researchers and technologists will find important information on the interaction of polymeric and non-polymeric inhibitors with a variety of scale forming crystals such as calcium phosphates, calcium carbonate, calcium oxalates, barium sulfate, calcium pyrophosphates, and calcium phosphonates. Moreover, the book delivers information to plant managers and formulators who would like to broaden and deepen their knowledge about processes involved in precipitation of sparingly soluble salts and learn more about the inhibitory aspects of various commercially available materials. Furthermore, experienced researchers will obtain fruitful and inspiring ideas from the easily accessible information about overlapping research areas, which will promote discoveries of new inhibitors (synthetic and/or natural) for the currently unmet challenges.

Psychologists of varying theoretical persuasions have long held that social experiences are critical to normal developmental trajectories and that the lack of such experiences is worthy of compensatory attention. Surprisingly, however, little empirical attention has been directed to the study of the psychological significance of social solitude for children. In an effort to shed new light on the meanings and developmental course of social solitude in childhood, a group of esteemed scholars from Europe and North America was invited to share and exchange information. An international audience of researchers actively involved in the study of social withdrawal and social inhibition or shyness in childhood was led in discussion by the scholars whose chapters are published in this volume. The editors hope that this offering stimulates continuing efforts to better understand the developmental meanings, causes, and courses of this childhood social dysfunction.

Excitation and Inhibition: Synaptic Morphology proposes the S-F hypothesis that emphasizes the relationship between structure and function of synapses. This book begins with an introduction to the notion of inhibition in the physiology of the nervous system and history of "synapse, followed by a discussion on the development of concept and morphological correlates of excitation and inhibition in relation to the S-F hypothesis. The mechanism of synaptic excitation and inhibition, physiological classification of neurons, and release mechanism of transmitters are also elaborated. This text describes the synaptic vesicles as a basis of transmitter, membrane recycle, transmission in the sympathetic ganglion, and transmitter substance. The criticism of S-F hypothesis, which deliberates the skeptical investigations of specialists regarding the simplicity and immaturity of the S-F hypothesis of synaptic morphology are provided at the end. This publication is beneficial to medical students and practitioners aiming to acquire knowledge of the physiology of synapses.

Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The present volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic.

This is a timely review of the mechanisms underlying the presynaptic control of synaptic transmission and the role they play in sensory and motor behavior. Early chapters offer a detailed account of the anatomy, biophysics, and physiology of synaptic transmission at the peripheral and centralsynapses, focusing on the presynaptic control of transmitter release. Later chapters explore the organization of neural pathways leading to the presynaptic inhibition of transmitter release in segmental reflex pathways. A final section provides examples of the operation of presynaptic controlmechanisms during specific sensory and motor functions in mammals, including humans. Integrating synaptic transmission and CNS functions at the systems level, this volume will be of particular interest to researchers studying both areas.