Sleep is one of the key underpinnings of human health yet sleep deprivation and impaired sleep are rampant in modern life. Sleep and wake are a true yin yang phenomenon, each affecting the other and together forming a harmonious whole. Healthy sleep is a whole-body process impacted by circadian rhythm, daily activities, and emotional well-being, among others. When properly aligned, these work in concert to produce restorative and refreshing sleep. When not in balance, however, sleep disorders result. Yet too often, the conventional medical approach to treatment of sleep disorders is compartmentalized, failing to recognize all of the complex interactions that are involved. The first book in its field, Integrative Sleep Medicine offers a true comprehensive approach to sleep and sleep disorders by delineating the many factors that interplay into healthy sleep. Health care practitioners can learn how to better manage their patients with sleep disorders by integrating complementary and conventional approaches. Using an evidence-based approach throughout, this book describes the basics of normal sleep, then delves into the foundations of integrative sleep medicine, including the circadian rhythm, mind-body sleep connection, light, dreaming, the gastrointestinal system, and botanicals and supplements. Specific sleep issues and disorders are then addressed from an integrative perspective, including insomnia, obstructive sleep apnea, sleep related movement disorders, and parasomnias.

"Sleep has been found to affect nearly all aspects of health, both individual and societal. Despite this, it has long been neglected in the medical literature until relatively recent times. Different perspectives of sleep are discussed, including historical views of sleep and alternative sleep patterns. The development of sleep as a medical specialty is described as are limitations to the conventional medical approach to sleep. The foundations of a truly integrative approach to sleep are enumerated"--

"Sleep has been found to affect nearly all aspects of health, both individual and societal. Despite this, it has long been neglected in the medical literature until relatively recent times. Different perspectives of sleep are discussed, including historical views of sleep and alternative sleep patterns. The development of sleep as a medical specialty is described as are limitations to the conventional medical approach to sleep. The foundations of a truly integrative approach to sleep are enumerated"--

This comprehensive resource covers the current thoughts and trends on narcolepsy, as well as cutting-edge evidence-based research. Updates from the previous edition include advances in diagnostic guidelines, treatments, protocols and clinical and psychosocial considerations. Aspects of narcolepsy relating to sleep medicine, neurology, psychiatry and public health are featured throughout the text. Narcolepsy, 2nd Edition provides clinicians and allied health professionals with patient management modalities, clinical and quality of life issues and best practices for health care delivery.

This timely volume provides the practitioner with evidence based treatments for many of the clinical problems encountered in integrated care. It applies the core concepts of stepped care to integrating brief mental health interventions as a way to address ongoing problems in the modern healthcare landscape. It sets out in depth the state of the healthcare crisis in terms of costs, staffing and training issues, integration logistics and management, system culture, and a variety of clinical considerations. Central to the book is a best-practice template for providing behavioral stepped care in medical settings, including screening and assessment, levels of intervention and treatment, referrals, and collaboration with primary care and other specialties. Using this format, contributors detail specific challenges of and science-based interventions for a diverse range of common conditions and issues, including: Depression. Anxiety disorders. Adherence to chronic obstructive pulmonary disorder management. Alcohol and other substance misuse. Attention deficit hyperactivity disorder. Chronic pain. Neurocognitive disorders. Paraphilias: problematic sexual interests.[WU3] Sexual abuse and PTSD in children. A solid roadmap for widescale reform, Principle-Based Stepped Care and Brief Psychotherapy for Integrated Care Settings is deeply informative reading for health psychologists, social workers, psychiatrists, and clinical psychologists. It also clarifies the research agenda for those seeking improvements in healthcare quality and delivery and patient satisfaction.

In this issue of Otolaryngologic Clinics, guest editors Drs. Michael D. Seidman and Marilene B. Wang bring their considerable expertise to the topic of Complementary and Integrative Medicine and Nutrition in Otolaryngology. Many patients use heath care approaches that are not part of conventional medical care or that may have origins outside of usual Western practice, while also using conventional health care. In this issue, top experts summarize the current knowledge of complementary and integrative medicine and nutrition as they relate to the care of patients in otolaryngology practices, providing a comprehensive resource that physicians and allied health providers can rely on for accurate patient counseling. - Contains 19 practice-oriented topics including diet and health; why otolaryngologists should be interested in psychedelic medicine; probiotics for otolaryngology disorders; sinus issues and natural alternatives; CIM and prevention of hearing loss; CIM and the voice; natural alternatives and the common cold/flu; otitis media; and more. - Provides in-depth clinical reviews on complementary and integrative medicine and nutrition in otolaryngology, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Neuroanatomists increasingly rely on techniques enabling them to manipulate genes in defined brain cell populations. In particular, engineered transgenes, which encode a variety of fluorescent reporter proteins can be inserted into the genome or delivered into desired brain regions using viral vectors, thereby allowing the labeling of molecularly-defined populations of neurons and/or glial cells. Transgenic technology can also be used to selectively delete genes in targeted neuronal populations or bi-directionally modulate their electrical excitability using optogenetic or chemogenetic techniques. One of the primary advantages of using transgenic reagents is to simplify the identification and tracing of targeted population of brain cells, which can be laborious using traditional techniques in neuroanatomy. In this research topic, we assembled up-to-date reviews and original articles that demonstrate the versatility and power of transgenic tools in advancing our knowledge of the nervous system, with a special emphasis on the application of transgenic technology to neuroanatomical questions.

This book is designed to meet the needs of nurse practitioners, other advanced practice nurses, and allied health professionals working in women’s health, primary care, and other specialties. The multiple roles the clinician embraces in menopause management include that of direct caregiver, manager of therapeutics, educator, and interdisciplinary team member or leader. This book provides updated, evidence based information on the menopause transition from the late reproductive stage to post-menopause to optimize the interaction of the clinician and the individual woman in each of those roles. Women’s lived experiences of menopause and women’s concerns regarding both the menopause transition and the choice of care options are included as critical components of shared therapy decisions. The review of natural menopause physiology and the variability of menopause symptoms are inclusive of diverse women and diverse trajectories. The impact of menopause on chronic disease, sleep, weight and nutrition, mood and cognition, urogenital health and sexuality, as well as vasomotor symptoms are each developed as individual topics by experts in those fields. Evidence based management using hormonal and non-hormonal options, and life-style and other complementary interventions are discussed with the most updated advantages and disadvantages of each treatment option. Consistent with advanced practice nursing theory, the approach is whole patient focused.

Integrated Clinical Orthodontics Integrates orthodontic diagnosis and treatment into the wider healthcare of the patient to achieve the highest possible standards of care Integrated Clinical Orthodontics offers an overview of clinical orthodontic theory and practice to equip clinicians to take an integrated approach to orthodontic practice. It presents the problems of orthodontics in an interdisciplinary context to describe how the potential complexity of dentofacial problems, the medical histories of patients, and a host of other factors contribute to orthodontic outcomes. The second edition has been expanded and thoroughly updated with new chapters and following an organized approach to the role of the orthodontist as part of a team. Cases in the book include orofacial deformities, sleep disorders, esthetic smile creation and temporomandibular joint problems. Orthodontic diagnosis and treatment are integrated into the wider health of the patient, including orthopedics, neurology, pediatrics, genetics and psychology, and the result is a modern, adaptable approach that places the patient and their needs at its center to achieve the highest possible standard of patient care. Readers of the second edition of Integrated Clinical Orthodontics will also find: New chapters on neuromuscular disorders, customized orthodontics, artificial intelligence, ethics and patient data Expanded content on special care in dentistry Guidance for the clinical interactions between orthodontics and other areas of dentistry and medicine Clinical implications and applications of the integrated approach in every chapter Integrated Clinical Orthodontics is an essential resource for clinical orthodontists and specialists in related medical and dental fields who wish to take the holistic view of orthodontic practice.

Adenosine A2A Receptor Antagonists, Volume 170 in the International Review of Neurobiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonist, Chemistry – agonists, antagonists, partial agonists, inverse agonists, Functional roles of adenosine receptors – biochemistry and neuronal plasticity, A2A and Depression, A2AR and glial function, The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signaling, How and why A2a receptor become to be a therapeutic target in Parkinson's disease therapy, and much more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in the International Review of Neurobiology - Updated release includes the latest information on Adenosine A2A Receptor Antagonists