Issues in Gastroenterology and Hepatology / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Additional Research. The editors have built Issues in Gastroenterology and Hepatology: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Gastroenterology and Hepatology: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Diabetes, Endocrinology, and Hepatology: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Hepatology. The editors have built Issues in Diabetes, Endocrinology, and Hepatology: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hepatology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Diabetes, Endocrinology, and Hepatology: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

In collaboration with Consulting Editor, Dr. Norman Gitlin, Dr. Vinod Rustgi has put together topics that provide a current clinical update on the treatment and management of patients with Hepatic Encephalopathy (HE). Experts in the field have contributetd clinical review articles on the following topics: Definition, Prevalence, and Epidemiology of HE; Pathophysiology of HE; Clinical Manifestations of HE; Laboratory Abnormalities of HE; Minimal or Subclinical HE; Prognosis of Prognosis of HE; Pharmacological Management of HE; Non-pharmacological Management of HE; Cost Burden of HE; Long-term management of HE: Modern Measures to Prevent Re-admission; Social Impact of HE; and Novel Therapies for HE. Readers will come away with the information they need to improve outcomes in patients with HE.

Textbook of Pediatric Gastroenterology, Hepatology and Nutrition is a comprehensive and up-to-date resource covering disorders of the liver and digestive system. This book is divided into three sections on gastroenterology, nutrition and hepatology respectively, encompassing 37 chapters. The book describes the pathophysiology of a range of paediatric disorders from diseases of the oesophagus and malnutrition, to chronic liver disease, as well as new genetic, metabolic and biochemical tests. Novel therapies are discussed for treatment of diseases such as tyrosinemia and neonatal haemochromtosis, and the hepatology section describes improved treatment for Hepatitis B and C in relation to liver transplantation. New modalities in endoscopy such as endoscopic ultrasound and capsule endoscopy in gastrointestinal disorders are also covered in detail. Enhanced by over 100 images and illustrations, Textbook of Pediatric Gastroenterology, Hepatology and Nutrition is an extensive guide to conditions of the digestive system and liver, which will assist postgraduates, paediatric gastroenterologists and other paediatricians in their practice. Key Points 37 chapters covering a range of disorders of the digestive system and liver Introduces new therapies and treatment modalities 100+ images and illustrations

In this issue of Clinics in Liver Disease, guest editor Dr. John V. Binu brings his considerable expertise to the topic of Primary Biliary Cholangitis. PBC leads to inflammation and scarring of the small bile ducts, and, if untreated, can lead to cirrhosis and liver failure. In this issue, top experts provide a state-of-the-art review of diagnosis and treatment for this chronic, progressive liver disorder. Contains 13 practice-oriented topics including genetics of primary biliary cholangitis; prognostic scoring systems in PBC; overlap syndromes and PBC; non-invasive evaluation of fibrosis and portal hypertension in PBC; treatment of PBC: first- and second-line therapies; novel therapies for PBC; and more. Provides in-depth clinical reviews on primary biliary cholangitis, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

This issue of Veterinary Clinics of North America: Small Animal Practice, with Editor Dr. Jonathan Lidbury, focuses on Hepatology. Article topics include: Laboratory evaluation of the liver; Getting the most out of liver biopsy; Hemostatic disorders associated with hepatobiliary disease; Acute liver injury; Canine copper associated chronic hepatitis; Canine idiopathic chronic hepatitis; Feline hepatic lipidosis; Hepatobiliary neoplasia in dogs and cats; Diagnostic imaging of the hepatobiliary system; Hepatic encephalopathy; Canine idiopathic chronic hepatitis; Feline cholangitis.

Dr. Flamm has invited a group of distinguished hepatologists to provide insight into the assessment of a variety of scenarios where clinical judgment based on experience and published literature is an invaluable addition to the care of individual patients. Articles included in the issue address the following topics: Evaluation and Management of Portal Vein Thrombosis, Liver Disease in the HIV patient, Hepatocellular Carcinoma, Evaluation of Renal Insufficiency in the Cirrhotic Patient, Contemporary Management of Autoimmune Hepatitis, Diagnosis and Treatment of Overlap Syndromes, Ins and Outs of Liver Imaging for the Gastroenterologist, Contemporary Assessment of Hepatic Fibrosis, A Primer on Liver Transplantation Immunosuppressive Agents for the Gastroenterologist, Evaluation of Jaundice in the Hospitalized Patient, Liver Disease in the Adolescent, Evaluation and Management of Hemochromatosis and How and When to Administer Hepatitis A and B Virus Vaccinations. These are all common contemporary reasons for consultations for Gastroenterologists and Hepatologists and this issue will address the issues in a pragmatic way.

A number of areas within liver transplant continue to evolve as the field matures. The advent of increasingly effective therapy for HCV will dramatically reduce the burden of recurrent disease within the next few years. HCC has become a well established indication for transplant with an increasing emphasis on adjuvant therapies to reduce the risk of tumor recurrence and potentially expand the acceptable limits of tumor burden amenable to liver transplant. Renal dysfunction is a frequent complication of decompensated liver disease and an important predictor of diminished post-transplant survival. Newer approached to therapy including terlipressin will reduce the impact of renal dysfunction in liver transplant candidates and potentially reduce the need for combined liver/kidney transplant. Increasing attention is being paid to role of comorbidities such as diabetes and hypertension on long-term recipient outcomes. Retransplantation remains a challenge with a variety of models available to predict outcomes. Cardiac disease pretransplant is an area of active investigation with newer entities such as cirrhotic cardiomyopathy a growing concern. These are some of many evolving issues in liver transplant which will be addressed to update our readers and which in turn will enhance the care of patients with liver disease.

Due to the current obesity epidemic, non-alcoholic fatty liver disease (NAFLD) is prevalent in a significant portion of the United States patient population. It is being increasingly recognized that NAFLD affects both adults and children and can progress to end stage liver disease with resultant cirrhosis, portal hypertension, and hepatocellular carcinoma. In addition, several extrahepatic conditions may be linked to NAFLD including cardiovascular disease, insulin requiring and type 2 diabetes mellitus, obstructive sleep apnea, colonic adenomas, hyperuricemia, vitamin D deficiency, hyperferritinemia, pancreatic steatosis, hypothyroidism, and polycystic ovarian syndrome. Therapies for NAFLD are evolving rapidly. This issue will analyze patient demographics, risk factors, pathophysiology, patient presentation, and treatments for NAFLD.

With collaboration of Dr. Stephen Krau, Consulting Editor, Dr. Benjamin Smallheer has created an issue of Nursing Clinics that provides a unique look at syndromes that cause organ failure or dysfunction. Expert authors contributed clinical reviews with up-to-date content in the following areas: Hyperglycemic Syndromes; Immunocompromised/Autoimmune Syndromes; Multiple Organ Dysfunction Syndrome; Fat Embolism Syndrome; Generalized Pain Syndromes; Malabsorptive syndromes; Munchausen/Munchausen by Proxy Syndrome ; Pickwickian Syndrome; Adrenal Syndromes; Male & Female Hypogonadism; Polycystic Ovarian Syndrome; Chest pain Syndromes (non-cardiac); Restless Leg syndrome; Degenerative/Debilitative Neurologic Syndromes; and Paroxysmal Sympathetic Hyperactivity Syndrome. Readers will come away with the clinical knowledge they need to improve patient outcomes.