This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

The Laboratory biosecurity guidance is a revision of the first edition of the WHO Biorisk management - Laboratory biosecurity guidance, 2006. As introduced in the 4th edition of the Laboratory biosafety manual (LBM4), the novel risk- and evidence-based approach is applied for biosecurity in this guidance. The guidance is intended to help researchers, biosafety/biosecurity officers and other laboratory personnel properly assess and manage risks inherent to high-consequence research. Furthermore, it contains a template for biosecurity risk assessment in the laboratory to prevent theft, misuse and unauthorized access to biological material, and also includes a two-tier approach for national oversight of biological risk management as well as a hybrid approach with risk- and list-based elements to regulate high-consequence material.

There are many guidelines, protocols and advisories that outline how biosafety and biosecurity can be adopted by institutions around the world. Whilst helpful, many of these are tailored to affluent Western nations. This leaves developing nations far behind since their laboratories and institutions are resource-scarce and biosafety and biosecurity are not mainstreamed entirely among the different laboratory workers, healthcare professionals, researchers, and academics. Biosafety and Biosecurity: Practical Insights and Applications for Low and Middle-Income Countries aims to bridge this gap by comprehensively summarizing the state and development of biosafety and biosecurity in developing and developed nations in a comparative analysis. This book includes basic concepts and principles of biosafety and biosecurity, including certification and legal frameworks, both international and local, and biosafety and biosecurity across disciplines including environmental, medical, and special topics that are relevant to countries with comparable conditions. This proposed book solves the problem of the lack of a prescribed professional title that comprehensively summarizes the state and development of biosafety and biosecurity throughout the world, allowing the reader a 360 view of the subject area. This book will appeal to a global audience of biorisk officers, health and safety professionals and specialists in the life sciences, health and allied fields, environmental science, engineering, and plant and animal agriculture.

Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.