Evidence-based medicine is a concept that has come to the fore in the past few years. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new pharmacological therapies are only used when large randomized trials have 'proven' that a particular drug is better than existing ones. This is also the case in surgical specialties, although surgery has traditionally seen a lack of use of this information, with individual surgeon's preferences being most influential in treatment choices. However, more recently, there has been a large expansion of trials and studies aimed at providing surgeons with information to guide their choices using firm evidence. This new edition has been revised and expanded to include new data where relevant, and also features a new chapter on pituitary surgery. Landmark Papers in Neurosurgery, Second Edition, remains a key collection of the most important trials and studies in neurosurgery, allowing the reader to rapidly extract key results, and making it essential reading for all neurosurgeons and trainees in the field.

The Congress of Neurological Surgeons Essential Papers in Neurosurgery brings to the neurosurgical community a unique collection of critically appraised neurosurgical papers shedding light on some of the most impactful studies in the history of the field. Separating the signal from the noise, this text offers papers that have shaped the practice of neurosurgery, selected through a rigorous process, and commented on by editorialists to reconcile conflicting points and summarize the take-home message of each study. Each paper is reviewed by a panel of two experts who provide editorials evaluating the strengths and weaknesses of the paper as well as the impact it had on the editorialist's personal practice of neurosurgery. This book is equally suited for neurosurgery residents, practicing neurosurgeons, and anyone interested in evidence-based clinical neuroscience. The body of literature covered in this book has in many ways defined the gold standards of neurosurgical practice and is a must-know for every student of neurosurgery.

Evidence-based medicine is a concept that is at the forefront of anaesthesia. Clinicians are increasingly encouraged to practise patient management based on available evidence in the scientific literature. For example, new anaesthesia methods, e.g. regional anaesthesia, are being used more frequently based on case studies that show the efficacy and cost-savings associated with the treatment. Additionally, considering that many anaesthetists are required to cover a range of areas, information discussing proven methods as well as pitfalls to avoid are valuable to all those working in the field. This book provides a detailed summary of the most important trials and studies in anaesthesia, ranging from neuroanaesthesia and anaesthesia for transplant, to paediatric and thoracic anaesthesia, allowing the reader to rapidly extract key results. Each chapter is written by a prominent anaesthetist in that particular field, and papers have been selected on a number of criteria, included impact factor, authors' choices, or even because the conclusions reached do not indicate best practice. With this wealth of information collected into this newest volume in the 'Landmark Papers in' series, Landmark Papers in Anaesthesia is essential reading for all practicing anaesthetists.

This book identifies the key scientific articles in the field of Intensive Care and explains why these papers are important in contemporary clinical management. Identifying those influential contributors who have shaped the practice of modern Intensive care practice, the book includes commentaries on 50 seminal papers in a wide range of areas. enal This an invaluable reference for trainees, fellows, and surgeons studying for exams, as well as for seasoned surgeons and physicians who want to stay current in their field.

Current understanding of neurological disease has been evolving over the past 150 years. With the increasing and earlier sub-specialization of neurology trainees, and their variable exposure to higher academic study, there is little opportunity to put this development into a historical context as a whole. Understanding the 'evidence-base', or appreciating the lack of it in some cases, is an important part of training but this is rarely presented in a palatable, entertaining form. Part of the Landmark Papers in series, this book brings together the ten most important papers for each sub-speciality within neurology, covering the full range of major neurological conditions. Papers have been selected by leading international experts, who not only summarize what each paper showed, but place them into a wider context that makes a coherent story of how their sub-speciality has developed.

Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice. Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine. Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.

Landmark Papers in Psychiatry traces the evolution of psychiatry as a scientific discipline. By summarizing over 100 watershed psychiatric papers this text gives historical context to the research trajectory of psychiatry.

With rapid advancements in human enhancement technologies, society struggles with many issues, such as definition, effects, participation, regulation, and control. Current and future initiatives in these technologies may not be in the participants’ best interests; therefore, it is imperative for research on humanitarian considerations to be available to those affiliated with this field. Global Issues and Ethical Considerations in Human Enhancement Technologies compiles prestigious research and provides a well-rounded composite of the field’s role in emerging technologies. Addressing both present and future concerns, this publication serves as a valuable reference work for researchers, students, professionals, and practitioners involved in computer science and the humanities, as well as many engaged in a humanities approach to metasystems, new artificial life, and robotics.

There has been an exponential increase in the volume and quality of published research relating to spine care over the last several decades. Among thousands of articles, a small fraction has been shown to be truly "game changing," forcing the entire field to pause and take notice. These landmark studies may describe a new procedure or surgical approach, evaluate the relative effects of known treatments or techniques, introduce a new classification system, or provide new insights into natural history or disease prognosis. Such studies form the foundations of spine surgery today.This book will be a useful reference not only to the established spine surgeon, but also to neurosurgery and orthopedic residents, as well as to spine surgery fellows as they continue to fortify their knowledge surrounding spinal disorders. Further, this will no doubt serve as a useful evidence-based resource for trainees studying for professional examinations and perhaps most importantly challenge and inspire clinicians to produce high-quality impactful research.