The management of cerebral aneurysms is still the subject of controversy in spite of recent dramatic advances in surgical techniques and neuro-intensive care. Currently, two main topics in this field have totally different aspects: 1. the management of unruptured cerebral aneurysms as a preventive medicine and 2. neurocrutical management of severe subarachnoid hemorrhage (SAH) after the rupture. These topics were discussed during the Swiss-Japanese Joint Conference in Zurich, Switzerland, in May 2001. Selected papers from this meeting are included in this volume presenting new clinical experiences in order to find out updated and proper ways to focus the treatment and providing updated information on neurocritical care aspects as well as endovascular and surgical treatment modalities carried out in daily practice in Zurich and Japan.

Two top neurosurgeons deliver complete, up-to-date guidance on the diagnosis and management of cerebrovascular aneurysms and malformations in this groundbreaking new resource. Stressing a multidisciplinary, team approach, this text presents a wealth of information on the treatment of aneurysms, the management of subarachnoid hemorrhage, techniques to occlude aneurysms*both surgical and endovascular*patient selection, and more.

Neurobiology of Disease is aimed at any basic scientist or clinician scientist teaching a course or conducting research on the basic science underlying the major neurological diseases. It provides an excellent overview of cutting-edge research on the fundamental disorders of the nervous system, including physiological and molecular aspects of dysfunction. The major categories of neurological disease are covered, and the chapters provide specific information about particular diseases exemplifying each of these categories. Sufficient clinical information is included to put into perspective the basic mechanisms discussed. The book assembles a world-class team of section editors and chapters written by acknowledged experts in their respective fields. - Provides cutting edge information about fundamental mechanisms underlying neurological diseases - Amply supplied with tables, illustrations and references - Includes supporting clinical information putting the mechanisms of disease into perspective

Microsurgery has brought about important changes and progress in the treatment of cere bral aneurysms in recent years. Only 12 years ago McKissock, one of the most experienced surgeons in the treatment of aneurysms pompared the results of operative and nonoperative treatment. He found that mortality and morbidity of cerebral aneurysms was not significantly affected by whether the patients have been operated upon or not. This view is held by many neursurgeons, and was confirmed by results of the Co-operative Study in 1969. In the review on treatment of aneurysms in Progress in Neurological Surgery in 1969, techniques such as encasement with plastic compounds, piloinjection, stereotactic copper or electric thrombosis and metallic thrombosis and profound hypothermia in anaesthesia were listed. In general, these techniques now seem to be of little more than historical interest. Progress in recent yeats has been so enormous that one may perhaps gain the impreSSion that the main problems in the treatment of aneurysms have been solved and that there are no more to be surmounted. This is dangerous and complacent thinking, such as Lord Moynihan indulged in during the thirties. For this reason we thought that the time had come to assemble a group of experts who could discuss the various unsolved and contro versial problems of aneurysm surgery in the friendly and relaxed atmosphere of a "work shop".

Direct from the Cleveland Clinic Foundation, Endovascular Techniques in the Management of Cerebrovascular Disease is intended for neurologists, neurosurgery fellows-in training, and practicing clinicians with an interest in endovascular procedures. This essential volume:Reviews equipment, devices, and therapeutic agents such as anti-coagulants and

Three topics of major interest for neursurgeons are covered in this volume of the Advances in Neurosurgery series, as the title suggests. First, neurosurgical standards of diagnosis and treatment are viewed from several points of view, including the legal one. Second, the many aspects of aneurysm surgery are dealt with: timing and grading, monitoring during the operation, postoperative vasospasm, Doppler sonography and new research in subarachnoid hemorrhage. Third, the diagnosis and treatment of malignant gliomas are discussed; there are preliminary reports on interstitial laser-assisted thermal therapy, immunotherapy and radiopharmaceutical substances as well as the standard forms of neurosurgical and radiation treatment.

In July 2008, European and Japanese specialists in neurosurgery, neurology, interventional neuroradiology and neurointensive care joined together to discuss the latest developments in the management of cerebrovascular disorders at the 4th European Japanese Joint Conference on Stroke Surgery, held in Helsinki, Finland. This collection of papers from the meeting deal with aneurysm surgery and management of subarachnoid hemorrhage and stroke, arterial dissection, intracranial arteriovenous malformations and fistulas, and microneurosurgical bypass and revascularization techniques.

Through the combination of the latest imaging modalities and microdevice delivery, interventional neuroradiologic techniques are currently revolutionizing the therapy for many of the most common neurological and neurosurgical disorders. Crossing the boundaries of classically delineated medical and surgical specialties including neurosurgery, neuroradiology, and neurology, interventional neuroradiology uses advanced neuroimaging combined with endovascular techniques to guide catheters and devices through blood vessels. These procedures can treat diseases involving structures of the head, neck, and central nervous system. These advances now provide noninvasive treatment for many disorders that were previously treated only with open surgical techniques, and make treatments possible for many patients—who until recently would have had no acceptable therapeutic options. Interventional Neuroradiology discusses CT, MR, and ultrasonographic evaluation of cerebrovascular disease, focusing on current neuroimaging evaluation of disorders. It emphasizes the integration of current neuroimaging information into decision-making and performance practices for neuroendovascular procedures. The book describes clinical techniques and includes the most current technical modifications for the varying devices in use today. Filled with scientifically concise illustrations, the text depicts pertinent neuroanatomy, imaging, and neuroendovascular techniques. Written by a panel of today's leading experts in the field of interventional neuroradiology, this volume demonstrates the potential of these lifesaving techniques.

Crossing the boundaries of classically delineated medical and surgical specialties including neurosurgery, neuroradiology, and neurology, Interventional Neuroradiology uses advanced neuroimaging combined with endovascular techniques to guide catheters and devices through blood vessels to treat disease involving structures of the head, neck, and cen