Marine Natural Products: Chemical and Biological Perspectives, Volume II, reviews the state of knowledge in the chemistry and biology of marine natural products. It attempts to bring together timely and critical reviews that are representative of major current researches and that, hopefully, will also foreshadow future trends. The first three chapters of this volume deal with marine carotenoids, steroids, and diterpenoids. This is followed by a chapter that examines a single phylum, the Coelenterata, and its metabolites. The Coelenterata is an almost exclusively marine phylum of some 9000 described living species. Research predicts that the coelenterates will yield a rich harvest of organic metabolites. The final chapter, which focuses on 13C NMR spectroscopy for structural elucidation, reveals the power of this instrumental method especially when applied to the difficult problems of polyhalogenated marine metabolites.

Marine Natural Products: Chemical and Biological Perspectives, Volume II, reviews the state of knowledge in the chemistry and biology of marine natural products. It attempts to bring together timely and critical reviews that are representative of major current researches and that, hopefully, will also foreshadow future trends. The first three chapters of this volume deal with marine carotenoids, steroids, and diterpenoids. This is followed by a chapter that examines a single phylum, the Coelenterata, and its metabolites. The Coelenterata is an almost exclusively marine phylum of some 9000 described living species. Research predicts that the coelenterates will yield a rich harvest of organic metabolites. The final chapter, which focuses on 13C NMR spectroscopy for structural elucidation, reveals the power of this instrumental method especially when applied to the difficult problems of polyhalogenated marine metabolites.

Volumes five and six of Bioorganic Marine Chemistry differ from their predecessors in two respects - they deal exclusively with laboratory synthesis of marine natural products and they represent the effort of a single author and his associates. The rationale for these departures is readily perceived. For several decades organic synthesis has without doubt been the most spectacular branch of organic chemistry. While the late R.B. Woodward's dictum - organic compounds can undergo only four basic reactions: they can gain electrons; they can lose electrons; they can be transformed with acid or with base - is still true, the wealth and variety of available reagents which will accomplish chemical transformations has reached staggering proportions. Little wonder then, that synthetic methodology has achieved a high degree of predictability and total synthesis of natural products has been successfully directed toward ever more challenging targets. As for the second point, that of single authorship, multiple authorship would invariably have led to gaps and overlaps, thus making it difficult to assemble and assess recent research in a systematic and comprehens ive fashion.

Bioactive Marine Natural Products is the first book available that covers all aspects of bioactive marine natural products. It fills the void in the literature for bioactive marine natural products. The book covers various aspects of marine natural products and it is hoped that all the major classes of bioactive compounds are included. Different classes of marine organisms and the separation and isolation techniques are discussed. The chemistry and biology of marine toxins, peptides, alkaloids, nucleosides and prostanoids are discussed in detail. Biological, toxicological and clinical evaluations are also dealt with to ensure that the book may be adopted at any stage by any practicing organic chemist or biologist, working in academia or in R and D divisions of pharmaceutical companies. Each chapter in the book includes an abstract to highlight the major points discussed in the text and concluding remarks are given. References to books, monographs, review articles and original papers are provided at the end of each chapter.

This work presents a definitive interpretation of the current status of and future trends in natural products—a dynamic field at the intersection of chemistry and biology concerned with isolation, identification, structure elucidation, and chemical characteristics of naturally occurring compounds such as pheromones, carbohydrates, nucleic acids, and enzymes. With more than 1,800 color figures, Comprehensive Natural Products II features 100% new material and complements rather than replaces the original work (©1999). Reviews the accumulated efforts of chemical and biological research to understand living organisms and their distinctive effects on health and medicine Stimulates new ideas among the established natural products research community—which includes chemists, biochemists, biologists, botanists, and pharmacologists Informs and inspires students and newcomers to the field with accessible content in a range of delivery formats Includes 100% new content, with more than 6,000 figures (1/3 of these in color) and 40,000 references to the primary literature, for a thorough examination of the field Highlights new research and innovations concerning living organisms and their distinctive role in our understanding and improvement of human health, genomics, ecology/environment, and more Adds to the rich body of work that is the first edition, which will be available for the first time in a convenient online format giving researchers complete access to authoritative Natural Products content

This volume contains the lectures presented at the NATO sponsored conference on "Marine Natural Products" held in Jersey, Channel Islands, U. K., October 12-17, 1976. The intent of the organising committee was to encourage a dialogue between organic chemists who study the metabolites of marine organisms and biolo gists, ecologists, and pharmacologists who study the effects of these metabolites on other organisms. A feature of the conference was the three workshop sessions on chemotaxonomy, applications of marine natural products, and chemical communication. The papers presented at the conference contain a mixture of original research in marine natural products and reviews of some of the more important subjects. The biologists were asked to present papers which could initiate new directions for marine natural products research. Their contributions to the meeting were warmly received by the chemists in the audience. We hope that this volume contains not only past and present research but a suggestion of future research trends. The conference was first suggested by Dr. E. D. Goldberg. The organising committee, Drs. G. Blunden, D. J. Faulkner, W.

This book is a compilation of the latest achievements of leading researchers in marine natural products with extremely diverse structures and biological activities. It presents discussions of isolation, structure elucidation, biosynthesis, total synthesis, and biochemical properties of the compounds with characteristic structures such as macrolides, cyclic depsipeptides, alkaloids, and water-soluble heterocyclic low-molecular-weight compounds, from sponges, bacteria, cyanobacteria, flagellates, and other such organisms. The book especially focuses on heterocyclic natural products as a title in the book series, Topics in Heterocyclic Chemistry.

1. B.J. Baker, R.G. Kerr: Biosynthesis of Marine Sterols 2. C.W.J. Chang, P.J. Scheuer: Marine Isocyano Compounds 3. G. Cimino, G. Sodano: Biosynthesis of Secondary Metabolites in Marine Molluscs 4. W.H. Gerwick, D.G. Nagle, P.J. Proteau: Oxylipins from Marine Invertebrates