Mass Identifications: Statistical Methods in Forensic Genetics summarizes the state-of-the-art in the field, including methods and recent development in genetics (sequencing). The book's authors focus on practical applications and implementation, helping readers determine how to approach the problem to identify individuals using DNA and statistically summarize evidence. Written by leading experts in the field for forensic scientists, geneticists, forensic anthropologists, and pathologists working with identifications, the book is ideal for scientists and practitioners in many areas. - Focuses on methods, challenges and solutions in DVI cases - Covers the use of DNA databases searches and the statistical evaluation of genetic comparisons - Includes exercises at the end of the book

How to design, execute, and interpret experiments for protein sequencing using mass spectrometry The rapid expansion of searchable protein and DNA databases in recent years has triggered an explosive growth in the application of mass spectrometry to protein sequencing. This timely and authoritative book provides professionals and scientists in biotechnology research with complete coverage of procedures for analyzing protein sequences by mass spectrometry, including step-by-step guidelines for sample preparation, analysis, and data interpretation. Michael Kinter and Nicholas Sherman present their own high-quality, laboratory-tested protocols for the analysis of a wide variety of samples, demonstrating how to carry out specific experiments and obtain fast, reliable results with a 99% success rate. Readers will get sufficient experimental detail to apply in their own laboratories, learn about the proper selection and operation of instruments, and gain essential insight into the fundamental principles of mass spectrometry and protein sequencing. Coverage includes: * Peptide fragmentation and interpretation of product ion spectra * Basic polyacrylamide gel electrophoresis * Preparation of protein digests for sequencing experiments * Mass spectrometric analysis using capillary liquid chromatography * Techniques for protein identification by database searches * Characterization of modified peptides using tandem mass spectrometry And much more

Commingling of human remains presents an added challenge to all phases of the forensic process. This book brings together tools from diverse sources within forensic science to offer a set of comprehensive approaches to handling commingled remains. It details the recovery of commingled remains in the field, the use of triage in the assessment of commingling, various analytical techniques for sorting and determining the number of individuals, the role of DNA in the overall process, ethical considerations, and data management. In addition, the book includes case examples that illustrate techniques found to be successful and those that proved problematic.

This book constitutes the refereed proceedings of the Third International Workshop on Algorithms in Bioinformatics, WABI 2003, held in Budapest, Hungary, in September 2003. The 36 revised full papers presented were carefully reviewed and selected from 78 submissions. The papers are organized in topical sections on comparative genomics, database searching, gene finding and expression, genome mapping, pattern and motif discovery, phylogenetic analysis, polymorphism, protein structure, sequence alignment, and string algorithms.

Renowned for being THE definitive resource for homicide investigators, Practical Homicide Investigation: Tactics, Procedures, and Forensic Techniques details the recognized protocols used by investigative divisions of major police departments throughout the world. The text is used in most police academies, including the FBI Academy in Quantico, Virginia. Now in its fifth edition, the book begins with a comprehensive discussion of homicide crime scenes and moves chronologically from initial police notification, the correct police response that follows, and the subsequent steps necessary to conduct an intelligent investigation. It then delves into the more technical aspects of homicide investigation, augmented with numerous pictures and full-color illustrations that involve pertinent case histories. This latest edition includes three new chapters along with fully revised chapters with new case histories and techniques that reflect the latest forensic methods and modern investigative procedures. Highlights of the Fifth Edition Include: Newly revised "Homicide Investigator’s Checklist" A new chapter on the latest DNA technology A rewritten chapter on equivocal death investigations that includes staged crime scenes Additional information on modes of death Fully updated chapters on death notifications, sex-related homicide, management for police administrators, suicide investigation, and narcotics-related and homosexually based homicides Over 920 photos and illustrations, 250 new photographs, and several new case histories Eminent author, lecturer, consultant, and expert witness Vernon J. Geberth incorporates his more than four and a half decades of real-world law enforcement experience in this quintessential reference. This classic and must-have resource provides the most vital information needed by detectives and police investigators responsible for cases in violent and sudden death. Remember: do it right the first time. You only get one chance. —Vernon J. Geberth, M.S., M.P.S., Homicide and Forensic Consultant, Author of Practical Homicide Investigation, and Series Editor of The Practical Aspects of Criminal and Forensic Investigations

This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also the limitations of these technologies. The editors, both well known within the scientific community, provide new insights into the biochemical and cellular mechanisms of cardiovascular disease, as well as covering the transition into clinical applications. In so doing, they highlight the various strategies and technical aspects so as to assist the growing number of researchers intending to utilize these approaches. The result is an excellent way of educating and informing graduate students, post-doctoral fellows as well as researchers in academia and industry about the latest developments in this area.