Life scientists today urgently need training in bioinformatics skills. Too many bioinformatics programs are poorly written and barely maintained--usually by students and researchers who've never learned basic programming skills. This practical guide shows postdoc bioinformatics professionals and students how to exploit the best parts of Python to solve problems in biology while creating documented, tested, reproducible software. Ken Youens-Clark, author of Tiny Python Projects (Manning), demonstrates not only how to write effective Python code but also how to use tests to write and refactor scientific programs. You'll learn the latest Python features and toolsâ??including linters, formatters, type checkers, and testsâ??to create documented and tested programs. You'll also tackle 14 challenges in Rosalind, a problem-solving platform for learning bioinformatics and programming. Create command-line Python programs to document and validate parameters Write tests to verify refactor programs and confirm they're correct Address bioinformatics ideas using Python data structures and modules such as Biopython Create reproducible shortcuts and workflows using makefiles Parse essential bioinformatics file formats such as FASTA and FASTQ Find patterns of text using regular expressions Use higher-order functions in Python like filter(), map(), and reduce()

Generate effective results in a variety of visually appealing charts using the plotting packages in Python About This Book Explore various tools and their strengths while building meaningful representations that can make it easier to understand data Packed with computational methods and algorithms in diverse fields of science Written in an easy-to-follow categorical style, this book discusses some niche techniques that will make your code easier to work with and reuse Who This Book Is For If you are a Python developer who performs data visualization and wants to develop existing knowledge about Python to build analytical results and produce some amazing visual display, then this book is for you. A basic knowledge level and understanding of Python libraries is assumed. What You Will Learn Gather, cleanse, access, and map data to a visual framework Recognize which visualization method is applicable and learn best practices for data visualization Get acquainted with reader-driven narratives and author-driven narratives and the principles of perception Understand why Python is an effective tool to be used for numerical computation much like MATLAB, and explore some interesting data structures that come with it Explore with various visualization choices how Python can be very useful in computation in the field of finance and statistics Get to know why Python is the second choice after Java, and is used frequently in the field of machine learning Compare Python with other visualization approaches using Julia and a JavaScript-based framework such as D3.js Discover how Python can be used in conjunction with NoSQL such as Hive to produce results efficiently in a distributed environment In Detail Python has a handful of open source libraries for numerical computations involving optimization, linear algebra, integration, interpolation, and other special functions using array objects, machine learning, data mining, and plotting. Pandas have a productive environment for data analysis. These libraries have a specific purpose and play an important role in the research into diverse domains including economics, finance, biological sciences, social science, health care, and many more. The variety of tools and approaches available within Python community is stunning, and can bolster and enhance visual story experiences. This book offers practical guidance to help you on the journey to effective data visualization. Commencing with a chapter on the data framework, which explains the transformation of data into information and eventually knowledge, this book subsequently covers the complete visualization process using the most popular Python libraries with working examples. You will learn the usage of Numpy, Scipy, IPython, MatPlotLib, Pandas, Patsy, and Scikit-Learn with a focus on generating results that can be visualized in many different ways. Further chapters are aimed at not only showing advanced techniques such as interactive plotting; numerical, graphical linear, and non-linear regression; clustering and classification, but also in helping you understand the aesthetics and best practices of data visualization. The book concludes with interesting examples such as social networks, directed graph examples in real-life, data structures appropriate for these problems, and network analysis. By the end of this book, you will be able to effectively solve a broad set of data analysis problems. Style and approach The approach of this book is not step by step, but rather categorical. The categories are based on fields such as bioinformatics, statistical and machine learning, financial computation, and linear algebra. This approach is beneficial for the community in many different fields of work and also helps you learn how one approach can make sense across many fields

Life scientists today urgently need training in bioinformatics skills. Too many bioinformatics programs are poorly written and barely maintained--usually by students and postdoc researchers who've never learned basic programming skills. This practical guide shows how to exploit the best parts of Python for solving problems in biology while also creating documented, tested, reproducible software. Ken Youens-Clark, author of Tiny Python Projects (Manning), demonstrates how to write effective Python code and how to use tests to write and refactor scientific programs. You'll learn the latest Python features and tools--such as linters, formatters, type checkers, and tests--to write documented and tested programs. Create command-line Python programs that document and validate parameters Write tests to verify refactor programs and confirm they're correct Address bioinformatics ideas using Python data structures (strings, lists, and sets) and modules such as Biopython Create reproducible shortcuts and workflows using makefiles Parse essential bioinformatics file formats such as FASTA, FASTQ, and SwissProt Find patterns of text using regular expressions Use higher-order functions in Python like filter() and map()

Available in print and online, this unique reference brings together all four fields of genetics, genomics, proteomics, and bioinformatics to meet your dynamic research requirements. It brings together the latest concepts in these vibrant areas and ensures a truly multidisciplinary approach. Topics include genetic variation and evolution, epigenetics, the human genome, expression profiling, proteome families, structural proteomics, gene finding/gene structure, protein function and annotation, and more. The work incorporates a vast amount of topical information, profiles cutting-edge techniques, and presents the very latest findings from an international team of over five hundred contributors. With articles for both students and more experienced scientists, this is a key reference source for everyone. Contains more than 450 articles covering all aspects of genomics, proteomics, bioinformatics and related technologies Includes a glossary containing over 550 clear and concise definitions "I am pleased to recommend it heartily as a essential reference tool...should remain the definitive work...for many years to come." THE CHEMICAL EDUCATOR "Jorde...and co-editors have done a remarkable job in coordinating this information, distilling it into a package that is both easy to navigate and over-flowing in discovery." ELECTRIC REVIEW

Discover modern, next-generation sequencing libraries from Python ecosystem to analyze large amounts of biological data Key Features Perform complex bioinformatics analysis using the most important Python libraries and applications Implement next-generation sequencing, metagenomics, automating analysis, population genetics, and more Explore various statistical and machine learning techniques for bioinformatics data analysis Book Description Bioinformatics is an active research field that uses a range of simple-to-advanced computations to extract valuable information from biological data. This book covers next-generation sequencing, genomics, metagenomics, population genetics, phylogenetics, and proteomics. You'll learn modern programming techniques to analyze large amounts of biological data. With the help of real-world examples, you'll convert, analyze, and visualize datasets using various Python tools and libraries. This book will help you get a better understanding of working with a Galaxy server, which is the most widely used bioinformatics web-based pipeline system. This updated edition also includes advanced next-generation sequencing filtering techniques. You'll also explore topics such as SNP discovery using statistical approaches under high-performance computing frameworks such as Dask and Spark. By the end of this book, you'll be able to use and implement modern programming techniques and frameworks to deal with the ever-increasing deluge of bioinformatics data. What you will learn Learn how to process large next-generation sequencing (NGS) datasets Work with genomic dataset using the FASTQ, BAM, and VCF formats Learn to perform sequence comparison and phylogenetic reconstruction Perform complex analysis with protemics data Use Python to interact with Galaxy servers Use High-performance computing techniques with Dask and Spark Visualize protein dataset interactions using Cytoscape Use PCA and Decision Trees, two machine learning techniques, with biological datasets Who this book is for This book is for Data data Scientistsscientists, Bioinformatics bioinformatics analysts, researchers, and Python developers who want to address intermediate-to-advanced biological and bioinformatics problems using a recipe-based approach. Working knowledge of the Python programming language is expected.

Includes, beginning Sept. 15, 1954 (and on the 15th of each month, Sept.-May) a special section: School library journal, ISSN 0000-0035, (called Junior libraries, 1954-May 1961). Also issued separately.

Explore the world of data science through Python and learn how to make sense of data About This Book Master data science methods using Python and its libraries Create data visualizations and mine for patterns Advanced techniques for the four fundamentals of Data Science with Python - data mining, data analysis, data visualization, and machine learning Who This Book Is For If you are a Python developer who wants to master the world of data science then this book is for you. Some knowledge of data science is assumed. What You Will Learn Manage data and perform linear algebra in Python Derive inferences from the analysis by performing inferential statistics Solve data science problems in Python Create high-end visualizations using Python Evaluate and apply the linear regression technique to estimate the relationships among variables. Build recommendation engines with the various collaborative filtering algorithms Apply the ensemble methods to improve your predictions Work with big data technologies to handle data at scale In Detail Data science is a relatively new knowledge domain which is used by various organizations to make data driven decisions. Data scientists have to wear various hats to work with data and to derive value from it. The Python programming language, beyond having conquered the scientific community in the last decade, is now an indispensable tool for the data science practitioner and a must-know tool for every aspiring data scientist. Using Python will offer you a fast, reliable, cross-platform, and mature environment for data analysis, machine learning, and algorithmic problem solving. This comprehensive guide helps you move beyond the hype and transcend the theory by providing you with a hands-on, advanced study of data science. Beginning with the essentials of Python in data science, you will learn to manage data and perform linear algebra in Python. You will move on to deriving inferences from the analysis by performing inferential statistics, and mining data to reveal hidden patterns and trends. You will use the matplot library to create high-end visualizations in Python and uncover the fundamentals of machine learning. Next, you will apply the linear regression technique and also learn to apply the logistic regression technique to your applications, before creating recommendation engines with various collaborative filtering algorithms and improving your predictions by applying the ensemble methods. Finally, you will perform K-means clustering, along with an analysis of unstructured data with different text mining techniques and leveraging the power of Python in big data analytics. Style and approach This book is an easy-to-follow, comprehensive guide on data science using Python. The topics covered in the book can all be used in real world scenarios.