The conception of race and the laws of Mendel. Different form of inheritance. The effect of mutations on the composition of a population in panmixia. The effect of selection on a population. Selection and mutations. The importance of the isolate for the composition of population. Isolates and race. Mutations, selection, and isolates.

An introduction to mathematical methods used in the study of population phenomena including models of total population and population age structure, models of random population events presented in terms of Markov chains, and methods used to uncover qualitative behavior of more complicated difference equations.

This text book, originally published in 1970, presents the field of population genetics, starting with elementary concepts and leading the reader well into the field. It is concerned mainly with population genetics in a strict sense and deals primarily with natural populations and less fully with the rather similar problems that arise in breading live stock and cul t i vat ed plans . The emphasis is on the behavior of genes and population attributes under natural selection where the most important measure is Darwinian fitness. This text is intended for graduatestudents and advanced undergraduates in genetics and population biology. This book steers a middle course between completely verbal biological arguments and the rigor of the mathematician. The first two-thirds of the book do not require advanced mathematical background. An ordinary knowledge of calculus will suffice. The latter parts of the book, which deal with population stochastically, use more advanced methods.

Mathematical models can be used to meet many of the challenges and opportunities offered by modern biology. The description of biological phenomena requires a range of mathematical theories. This is the case particularly for the emerging field of systems biology. Mathematical Methods in Biology and Neurobiology introduces and develops these mathematical structures and methods in a systematic manner. It studies: • discrete structures and graph theory • stochastic processes • dynamical systems and partial differential equations • optimization and the calculus of variations. The biological applications range from molecular to evolutionary and ecological levels, for example: • cellular reaction kinetics and gene regulation • biological pattern formation and chemotaxis • the biophysics and dynamics of neurons • the coding of information in neuronal systems • phylogenetic tree reconstruction • branching processes and population genetics • optimal resource allocation • sexual recombination • the interaction of species. Written by one of the most experienced and successful authors of advanced mathematical textbooks, this book stands apart for the wide range of mathematical tools that are featured. It will be useful for graduate students and researchers in mathematics and physics that want a comprehensive overview and a working knowledge of the mathematical tools that can be applied in biology. It will also be useful for biologists with some mathematical background that want to learn more about the mathematical methods available to deal with biological structures and data.

Brings mathematics to bear on your real-world, scientific problems Mathematical Methods in Interdisciplinary Sciences provides a practical and usable framework for bringing a mathematical approach to modelling real-life scientific and technological problems. The collection of chapters Dr. Snehashish Chakraverty has provided describe in detail how to bring mathematics, statistics, and computational methods to the fore to solve even the most stubborn problems involving the intersection of multiple fields of study. Graduate students, postgraduate students, researchers, and professors will all benefit significantly from the author's clear approach to applied mathematics. The book covers a wide range of interdisciplinary topics in which mathematics can be brought to bear on challenging problems requiring creative solutions. Subjects include: Structural static and vibration problems Heat conduction and diffusion problems Fluid dynamics problems The book also covers topics as diverse as soft computing and machine intelligence. It concludes with examinations of various fields of application, like infectious diseases, autonomous car and monotone inclusion problems.

Complex diseases involve most aspects of population biology, including genetics, demographics, epidemiology, and ecology. Mathematical methods, including differential, difference, and integral equations, numerical analysis, and random processes, have been used effectively in all of these areas. The aim of this book is to provide sufficient background in such mathematical and computational methods to enable the reader to better understand complex systems in biology, medicine, and the life sciences. It introduces concepts in mathematics to study population phenomena with the goal of describing complicated aspects of a disease, such as malaria, involving several species. The book is based on a graduate course in computational biology and applied mathematics taught at the Courant Institute of Mathematical Sciences in fall 2010. The mathematical level is kept to essentially advanced undergraduate mathematics, and the results in the book are intended to provide readers with tools for performing more in-depth analysis of population phenomena.

This book covers those areas of theoretical population genetics that can be investigated rigorously by elementary mathematical methods. I have tried to formulate the various models fairly generally and to state the biological as sumptions quite explicitly. I hope the choice and treatment of topics will en able the reader to understand and evaluate detailed analyses of many specific models and applications in the literature. Models in population genetics are highly idealized, often even over idealized, and their connection with observation is frequently remote. Further more, it is not practicable to measure the parameters and variables in these models with high accuracy. These regrettable circumstances amply justify the use of appropriate, lucid, and rigorous approximations in the analysis of our models, and such approximations are often illuminating even when exact solu tions are available. However, our empirical and theoretical limitations justify neither opaque, incomplete formulations nor unconvincing, inadequate analy ses, for these may produce uninterpretable, misleading, or erroneous results. Intuition is a principal source of ideas for the construction and investigation of models, but it can replace neither clear formulation nor careful analysis. Fisher (1930; 1958, pp. x, 23-24, 38) not only espoused similar ideas, but he recognized also that our concepts of intuition and rigor must evolve in time. The book is neither a review of the literature nor a compendium of results. The material is almost entirely self-contained. The first eight chapters are a thoroughly revised and greatly extended version of my published lecture notes (Nagylaki, 1977a).

Social life of bacteria is in the focus of recent research. Bacteria are simple enough to be accessible by science, but still complex enough to show cooperation, division of labor, bet-hedging, cross-talk and synchronized activities, and a rich variety of social traits. A central question of evolutionary theory is the explanation why this social life did develop, and why these systems are evolutionary stable. This book introduces the reader into the theory of evolution, covering classical models and as well as recent developments. The theory developed is used to represent the up-to-date understanding of social bacteria.This book will be useful for students and lecturers interested in mathematical evolutionary theory, as well as for researchers as a reference.