Patients are not alike! This simple truth is often ignored in the analysis of me- cal data, since most of the time results are presented for the “average” patient. As a result, potential variability between patients is ignored when presenting, e.g., the results of a multiple linear regression model. In medicine there are more and more attempts to individualize therapy; thus, from the author’s point of view biostatis- cians should support these efforts. Therefore, one of the tasks of the statistician is to identify heterogeneity of patients and, if possible, to explain part of it with known explanatory covariates. Finite mixture models may be used to aid this purpose. This book tries to show that there are a large range of applications. They include the analysis of gene - pression data, pharmacokinetics, toxicology, and the determinants of beta-carotene plasma levels. Other examples include disease clustering, data from psychophysi- ogy, and meta-analysis of published studies. The book is intended as a resource for those interested in applying these methods.

An up-to-date, comprehensive account of major issues in finitemixture modeling This volume provides an up-to-date account of the theory andapplications of modeling via finite mixture distributions. With anemphasis on the applications of mixture models in both mainstreamanalysis and other areas such as unsupervised pattern recognition,speech recognition, and medical imaging, the book describes theformulations of the finite mixture approach, details itsmethodology, discusses aspects of its implementation, andillustrates its application in many common statisticalcontexts. Major issues discussed in this book include identifiabilityproblems, actual fitting of finite mixtures through use of the EMalgorithm, properties of the maximum likelihood estimators soobtained, assessment of the number of components to be used in themixture, and the applicability of asymptotic theory in providing abasis for the solutions to some of these problems. The author alsoconsiders how the EM algorithm can be scaled to handle the fittingof mixture models to very large databases, as in data miningapplications. This comprehensive, practical guide: * Provides more than 800 references-40% published since 1995 * Includes an appendix listing available mixture software * Links statistical literature with machine learning and patternrecognition literature * Contains more than 100 helpful graphs, charts, and tables Finite Mixture Models is an important resource for both applied andtheoretical statisticians as well as for researchers in the manyareas in which finite mixture models can be used to analyze data.

Mixture Modelling for Medical and Health Sciences provides a direct connection between theoretical developments in mixture modelling and their applications in real world problems. The book describes the development of the most important concepts through comprehensive analyses of real and practical examples taken from real-life research problems in

This book focuses on recent advances, approaches, theories and applications related to mixture models. In particular, it presents recent unsupervised and semi-supervised frameworks that consider mixture models as their main tool. The chapters considers mixture models involving several interesting and challenging problems such as parameters estimation, model selection, feature selection, etc. The goal of this book is to summarize the recent advances and modern approaches related to these problems. Each contributor presents novel research, a practical study, or novel applications based on mixture models, or a survey of the literature. Reports advances on classic problems in mixture modeling such as parameter estimation, model selection, and feature selection; Present theoretical and practical developments in mixture-based modeling and their importance in different applications; Discusses perspectives and challenging future works related to mixture modeling.

The paper exploits panel data finite mixture (latent class) models to measure consumer equity in healthcare access and utilization. The finite mixture approach accounts for unobservable consumer heterogeneity, while generalized linear models address a retransformation problem of logged dependent variable. Using the data of the Japan Household Panel Survey (2009–2014), we discover that consumers separate into latent classes in the binary choice models for healthcare use and generalized linear models for outpatient/inpatient healthcare expenditure. The results reveal that healthcare access in Japan is pro-poor for the most sick consumers, while utilization of outpatient care is equitable with respect to disposable income.

This book provides a general theoretical background for constructing the recursive Bayesian estimation algorithms for mixture models. It collects the recursive algorithms for estimating dynamic mixtures of various distributions and brings them in the unified form, providing a scheme for constructing the estimation algorithm for a mixture of components modeled by distributions with reproducible statistics. It offers the recursive estimation of dynamic mixtures, which are free of iterative processes and close to analytical solutions as much as possible. In addition, these methods can be used online and simultaneously perform learning, which improves their efficiency during estimation. The book includes detailed program codes for solving the presented theoretical tasks. Codes are implemented in the open source platform for engineering computations. The program codes given serve to illustrate the theory and demonstrate the work of the included algorithms.

This book focuses on recent advances, approaches, theories, and applications related Hidden Markov Models (HMMs). In particular, the book presents recent inference frameworks and applications that consider HMMs. The authors discuss challenging problems that exist when considering HMMs for a specific task or application, such as estimation or selection, etc. The goal of this volume is to summarize the recent advances and modern approaches related to these problems. The book also reports advances on classic but difficult problems in HMMs such as inference and feature selection and describes real-world applications of HMMs from several domains. The book pertains to researchers and graduate students, who will gain a clear view of recent developments related to HMMs and their applications.

Cluster analysis comprises a range of methods for classifying multivariate data into subgroups. By organizing multivariate data into such subgroups, clustering can help reveal the characteristics of any structure or patterns present. These techniques have proven useful in a wide range of areas such as medicine, psychology, market research and bioinformatics. This fifth edition of the highly successful Cluster Analysis includes coverage of the latest developments in the field and a new chapter dealing with finite mixture models for structured data. Real life examples are used throughout to demonstrate the application of the theory, and figures are used extensively to illustrate graphical techniques. The book is comprehensive yet relatively non-mathematical, focusing on the practical aspects of cluster analysis. Key Features: Presents a comprehensive guide to clustering techniques, with focus on the practical aspects of cluster analysis Provides a thorough revision of the fourth edition, including new developments in clustering longitudinal data and examples from bioinformatics and gene studies./li> Updates the chapter on mixture models to include recent developments and presents a new chapter on mixture modeling for structured data Practitioners and researchers working in cluster analysis and data analysis will benefit from this book.

This book includes selected peer-reviewed papers presented at the International Conference on Trends in Electronics and Health Informatics (TEHI 2022), held at University of Puebla, Puebla, México, during December 7–9, 2022. The book is broadly divided into five sections—artificial intelligence and soft computing, healthcare informatics, Internet of things and data analytics, electronics, and communications.

The Wiley-Interscience Paperback Series consists of selected books that have been made more accessible to consumers in an effort to increase global appeal and general circulation. With these new unabridged softcover volumes, Wiley hopes to extend the lives of these works by making them available to future generations of statisticians, mathematicians, and scientists. "For both applied and theoretical statisticians as well as investigators working in the many areas in which relevant use can be made of discriminant techniques, this monograph provides a modern, comprehensive, and systematic account of discriminant analysis, with the focus on the more recent advances in the field." –SciTech Book News ". . . a very useful source of information for any researcher working in discriminant analysis and pattern recognition." –Computational Statistics Discriminant Analysis and Statistical Pattern Recognition provides a systematic account of the subject. While the focus is on practical considerations, both theoretical and practical issues are explored. Among the advances covered are regularized discriminant analysis and bootstrap-based assessment of the performance of a sample-based discriminant rule, and extensions of discriminant analysis motivated by problems in statistical image analysis. The accompanying bibliography contains over 1,200 references.