The three-volume set LNCS 6891, 6892 and 6893 constitutes the refereed proceedings of the 14th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2011, held in Toronto, Canada, in September 2011. Based on rigorous peer reviews, the program committee carefully selected 251 revised papers from 819 submissions for presentation in three volumes. The first volume includes 86 papers organized in topical sections on robotics, localization and tracking and visualization, planning and image guidance, physical modeling and simulation, motion modeling and compensation, and segmentation and tracking in biological images.

The two-volume set LNCS 5761 and LNCS 5762 constitute the refereed proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2009, held in London, UK, in September 2009. Based on rigorous peer reviews, the program committee carefully selected 259 revised papers from 804 submissions for presentation in two volumes. The first volume includes 125 papers divided in topical sections on cardiovascular image guided intervention and robotics; surgical navigation and tissue interaction; intra-operative imaging and endoscopic navigation; motion modeling and image formation; image registration; modeling and segmentation; image segmentation and classification; segmentation and atlas based techniques; neuroimage analysis; surgical navigation and robotics; image registration; and neuroimage analysis: structure and function.

The13thInternationalConferenceonMedicalImageComputingandComputer- Assisted Intervention, MICCAI 2010, was held in Beijing, China from 20-24 September,2010.ThevenuewastheChinaNationalConventionCenter(CNCC), China’slargestandnewestconferencecenterwith excellentfacilities andaprime location in the heart of the Olympic Green, adjacent to characteristic constr- tions like the Bird’s Nest (National Stadium) and the Water Cube (National Aquatics Center). MICCAI is the foremost international scienti?c event in the ?eld of medical image computing and computer-assisted interventions. The annual conference has a high scienti?c standard by virtue of the threshold for acceptance, and accordingly MICCAI has built up a track record of attracting leading scientists, engineersandcliniciansfromawiderangeoftechnicalandbiomedicaldisciplines. This year, we received 786 submissions, well in line with the previous two conferences in New York and London. Three program chairs and a program committee of 31 scientists, all with a recognized standing in the ?eld of the conference, were responsible for the selection of the papers. The review process was set up such that each paper was considered by the three program chairs, two program committee members, and a minimum of three external reviewers. The review process was double-blind, so the reviewers did not know the identity of the authors of the submission. After a careful evaluation procedure, in which all controversialand gray area papers were discussed individually, we arrived at a total of 251 accepted papers for MICCAI 2010, of which 45 were selected for podium presentation and 206 for poster presentation. The acceptance percentage (32%) was in keeping with that of previous MICCAI conferences. All 251 papers are included in the three MICCAI 2010 LNCS volumes.

The three-volume set LNCS 7510, 7511, and 7512 constitutes the refereed proceedings of the 15th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2012, held in Nice, France, in October 2012. Based on rigorous peer reviews, the program committee carefully selected 252 revised papers from 781 submissions for presentation in three volumes. The third volume includes 79 papers organized in topical sections on diffusion imaging: from acquisition to tractography; image acquisition, segmentation and recognition; image registration; neuroimage analysis; analysis of microscopic and optical images; image segmentation; diffusion weighted imaging; computer-aided diagnosis and planning; and microscopic image analysis.

The three-volume set LNCS 9349, 9350, and 9351 constitutes the refereed proceedings of the 18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015, held in Munich, Germany, in October 2015. Based on rigorous peer reviews, the program committee carefully selected 263 revised papers from 810 submissions for presentation in three volumes. The papers have been organized in the following topical sections: quantitative image analysis I: segmentation and measurement; computer-aided diagnosis: machine learning; computer-aided diagnosis: automation; quantitative image analysis II: classification, detection, features, and morphology; advanced MRI: diffusion, fMRI, DCE; quantitative image analysis III: motion, deformation, development and degeneration; quantitative image analysis IV: microscopy, fluorescence and histological imagery; registration: method and advanced applications; reconstruction, image formation, advanced acquisition - computational imaging; modelling and simulation for diagnosis and interventional planning; computer-assisted and image-guided interventions.

The 11th International Conference on Medical Imaging and Computer Assisted Intervention, MICCAI 2008, was held at the Helen and Martin Kimmel Center of New York University, New York City, USA on September 6–10, 2008. MICCAI is the premier international conference in this domain, with - depth papers on the multidisciplinary ?elds of biomedical image computing and analysis, computer assisted intervention and medical robotics. The conference brings together biological scientists, clinicians, computer scientists, engineers, mathematicians, physicists and other interested researchers and o?ers them a forum to exchange ideas in these exciting and rapidly growing ?elds. The conference is both very selective and very attractive: this year we - ceived a record number of 700 submissions from 34 countries and 6 continents, fromwhich258papers were selectedfor publication,whichcorrespondsto a s- cess rate of approximately 36%. Some interesting facts about the distribution of submitted and accepted papers are shown graphically at the end of this preface. The paper selection process this year was based on the following procedure, which included the introduction of several novelties over previous years. 1. A ProgramCommittee (PC) of 49 members was recruited by the Program Chairs,to getthenecessarybody ofexpertiseandgeographicalcoverage.All PC members agreed in advance to participate in the ?nal paper selection process. 2. Key words grouped in 7 categories were used to describe the content of the submissions and the expertise of the reviewers.

Annotation The two-volume set LNCS 5241 and LNCS 5242 constitute the refereed proceedings of the 11th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2008, held in New York, NY, USA, in September 2008.The program committee carefully selected 258 revised papers from numerous submissions for presentation in two volumes, based on rigorous peer reviews. The first volume includes 127 papers related to medical image computing, segmentation, shape and statistics analysis, modeling, motion tracking and compensation, as well as registration. The second volume contains 131 contributions related to robotics and interventions, statistical analysis, segmentation, intervention, modeling, and registration.

As one of the most important tasks in biomedical imaging, image segmentation provides the foundation for quantitative reasoning and diagnostic techniques. A large variety of different imaging techniques, each with its own physical principle and characteristics (e.g., noise modeling), often requires modality-specific algorithmic treatment. In recent years, substantial progress has been made to biomedical image segmentation. Biomedical image segmentation is characterized by several specific factors. This book presents an overview of the advanced segmentation algorithms and their applications.

The seven-volume set LNCS 12261, 12262, 12263, 12264, 12265, 12266, and 12267 constitutes the refereed proceedings of the 23rd International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2020, held in Lima, Peru, in October 2020. The conference was held virtually due to the COVID-19 pandemic. The 542 revised full papers presented were carefully reviewed and selected from 1809 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: machine learning methodologies Part II: image reconstruction; prediction and diagnosis; cross-domain methods and reconstruction; domain adaptation; machine learning applications; generative adversarial networks Part III: CAI applications; image registration; instrumentation and surgical phase detection; navigation and visualization; ultrasound imaging; video image analysis Part IV: segmentation; shape models and landmark detection Part V: biological, optical, microscopic imaging; cell segmentation and stain normalization; histopathology image analysis; opthalmology Part VI: angiography and vessel analysis; breast imaging; colonoscopy; dermatology; fetal imaging; heart and lung imaging; musculoskeletal imaging Part VI: brain development and atlases; DWI and tractography; functional brain networks; neuroimaging; positron emission tomography