Hair loss affects millions of people worldwide and goes far beyond cosmetic concerns. For many, it represents a significant burden that has a significant impact on self-confidence and quality of life. The search for effective treatments is therefore not only a scientific, but also a socially relevant task. This book is dedicated to current and future therapeutic approaches to hair loss and offers a sound, scientifically based foundation for a topic that is currently occupying medicine and research more than ever before. The reader is given a thorough introduction to the physiological, molecular and genetic basis of hair growth as well as to the complex mechanisms of hair loss. New insights into the underlying processes are presented in detail – from hormonal and immunological to genetic influences that can lead to thinning or loss of hair. On this basis, a broad spectrum of therapeutic approaches is presented that have the potential to significantly influence progress in hair therapy. The first part of the book focuses on established treatment approaches. The reader is brought up to date with current clinical practice and given valuable insights into the efficacy and limitations of the therapies approved to date. The second, future-oriented part of the book introduces the state-of-the-art and innovative developments currently being investigated in preclinical and clinical research. Targeted biologics and gene technology approaches that are geared towards regeneration and hair growth are discussed here. These include novel forms of therapy such as the inhibition of specific signalling pathways that are thought to be responsible for hair loss, or the use of stem cell therapies that open up promising new perspectives. The potential, but also the challenges, of gene therapy and the application of personalised medicine to the treatment of hair loss are examined in detail. A read that combines scientific depth and comprehensibility and establishes itself as a work for anyone looking for well-founded answers and new perspectives on hair loss therapy.

Hair disorders have become a central social and psychological issue and patients now have increasing demands and expectations. Written by world-renowned experts, this lavishly illustrated book provides the latest scientific aspects of hair biology, up to date knowledge on hair diagnosis and treatment options as well as hair removal and restoration techniques. The content is divided into three sections: basic aspects of hair growth; hair and scalp disorders; and fotoepilation, surgery and hair cosmetics. In addition, coverage is enhanced with unique sections on hair in different ages and in art, on ethnic hair and in forensic investigations.

Written by a medical doctor, a naturopath, and a registered pharmacist, Smart Medicine for Healthier Living is a complete A-to-Z guide to the most common disorders and their treatments, using both alternative care and conventional medicine. Comprehensive and easy-to-follow, Smart Medicine for Healthier Living is divided into three parts. Part one explains the full spectrum of approaches used to effectively treat common health problems. It provides an overview of the history, fundamentals, and uses of conventional medicine, herbal medicine, homeopathy, acupressure, aromatherapy, diet, and nutritional supplements. It also includes a helpful section on home and personal safety. Part two contains a comprehensive A-to-Z listing of various health problems. Each entry clearly explains the problem and offers specific advice using a variety of approaches. Part three provides step-by-step guidance on using the many therapies and procedures suggested for each health problem. Smart Medicine for Healthier Living is a reliable source that you and your family can turn to time and time again, whenever the need arises.

You could read every textbook available on hair growth and disorders, and still not be able to treat hair loss effectively. In every art, there are many techniques, but few principles. The only way to achieve success is to have a firm foundation of principles to build upon, and the right attitude about how to achieve your goals. This book offers a detailed guide that goes beyond the technical aspects of trichology and evidence based medicine, providing specialists and primary care physicians experienced in the basic management of hair loss with the additional know-how they need to master the ultimate challenge of difficult hair loss patients. First, the prerequisites for successful management of hair loss are reviewed – basically, making a diagnosis and understanding the patient and his or her problem. Then, guidelines on the management of difficult dermatologic conditions and of psychopathological disorders associated with hair loss are provided. Lastly, important aspects of follow-up are covered–specifically the problems of adverse effects, patient non-compliance, and their management–before concluding with exemplary case studies of successful treatment of alopecia and related conditions.

This second of three related volumes, designed as a reference tool for the understanding and treatment of Androgenetic Alopecia and Female Pattern Hair Loss (AGA/FPHL), is structured in 4 sections: 63 dedicated chapters covering every aspect of medical (non-surgical, non-invasive) and nutritional treatment options and clinical effects. FDA-approved hair growth drugs, every frequently prescribed "off-label" or experimental drug, hormones, cosmeceuticals, and popular fraudulent controversial products are all presented in 26 chapters, with figures, tables, algorithms, and thousands of fully updated and balanced literature citations. Filling a gap in the latest literature, Androgenetic Alopecia From A to Z: Drugs, Herbs, Nutrition, and Supplements includes a thorough review of lifestyle and nutritional factors specifically affecting AGA/FPHL, including excessive caloric intake, high-fat diets, caloric deprivation, alcohol abuse, and smoking. The intricate effects of nutrition on hair loss, one of the most neglected and misunderstood fields in Dermatology, are presented as well, with a plethora of clinically valuable information: why food supplements are so popular, the regulatory minefield of supplements, and the life-threatening perils of nutritional supplementation, are all reviewed extensively. Each vitamin, major mineral, and trace element implicated in follicular physiology is reviewed in altogether 24 dedicated chapters according to their specific effects on the hair follicle, food sources, dietary recommendations, and the impact of deficiency or excess. This volume includes a comprehensive chapter on the understanding of Complementary-Alternative Medicine (CAM). CAM is an umbrella term for methods that lie outside evidence-based medicine and a part of a societal trend towards the rejection of science as a method of determining facts. The pitfalls and challenges in understanding botanicals with reported hair growth properties, from publication bias to lack of standardization, as well as their unpredictable pharmacological and physiological effects, are all explained in detail. Finally, all popular botanical products reported to possess hair growth properties are appraised in 14 dedicated chapters, each including a detailed review of the general effects, the suggested biochemical mechanisms, claimed actions on the hair follicle, all available studies, and hundreds of literature citations. This carefully crafted book will be an invaluable reference tool for dermatologists and all clinical practitioners dealing with Androgenetic Alopecia and Female Pattern Hair Loss and will help them answer challenging patient questions, debunk myths on hair growth drugs, and supplements and navigate patients towards effective and safe treatment schemes.

Functional foods and nutraceuticals, dietary supplements, and natural antioxidants have established their potential roles in the protection of human health against disease. Nutraceuticals and Functional Foods in Human Health and Disease Prevention examines the benefits, efficacy, and success of properly designed nutraceuticals and functional foods

Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. - Presents fundamental concepts and factors affecting choice for plant-based products - Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward - Highlights recent advances in computational-based drug discovery - Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Written by physicians who are experts in both traditional and complementary medicine, Integrative Medicine, 5th Edition, uses a clinical, disease-oriented approach to safely and effectively incorporate alternative therapies into primary care practice. Drawing on available scientific evidence and the authors' first-hand experiences, it covers therapies such as botanicals, supplements, mind-body, lifestyle choices, nutrition, exercise, spirituality, and other integrative medicine modalities. This highly regarded reference offers practical guidance for reducing costs and improving patient care while focusing on prevention and wellness for a better quality of life. - Explains how to make the best use of integrative medicine and the mechanisms by which these therapeutic modalities work, keeping you at the forefront of the trend toward integrative health care. - Templated chapters make it quick and easy to find key information such as dosing, pearls, the Prevention Prescription, and Therapeutic Reviews that incorporates the Evidence vs Harm Icon. - Uses the reliable SORT method (Strength of Recommendation Taxonomy) to provide evidence-based ratings, grading both the evidence and the relative potential harm. - Thoroughly updated, ensuring that you remain well informed regarding the latest evidence. - Contains 10 new chapters covering clinician resilience, supporting immunity, NASH/fatty liver, hair loss, rethinking the movement prescription, compassion practices, prescribing low-dose naltrexone, psychedelics, tapering off PPIs and opioids, as well as an expanded osteopathy chapter. - Covers timely topics aimed at reducing the epidemics of polypharmacy and opioid overuse, as well as supporting immunity in the face of infectious diseases. - Provides online access to multiple-choice questions for every chapter—perfect for board exam review. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.