This book presents tools and techniques for the development of miniature biosensors and their applications. The initial chapters discuss the advancements in the development of the transduction techniques, including optical, electrochemical, and piezoelectric, which are used for miniaturized biosensors. The book also reviews several technologies, such as nanotechnology, nanobiotechnology, immune-technology, DNA-technology, micro-manufacturing technology, electronic-circuit technology to increase the miniaturization and sensitivity of the biosensor platform. Subsequently, the chapters illustrate the applications of miniaturized biosensing systems in point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics, and biomedical research. Towards the end, the book discusses the advanced applications of biosensors in water quality monitoring, especially on-line detection systems and on-site detection of pesticides, heavy metals and bacteria in water. This book is an invaluable source for scientists working in biochemical engineering, bioengineering, and biomedical engineering in academia and industry.

Evidently, electrochemical sensing has revolutionized the electroanalytical detections in the world. Since the 19th century, a huge amount of growth has been visible on various fronts, such as biosensors, energy devices, semiconductor devices, communication, embedded systems, sensors etc. However, the major research gap lies in the fact that most of the reported literatures are bulk systems; hence there are limitations for practical applications. Research in these domains has been carried out by both academia and industry, whereby academics is the backbone whose intellectual outputs have been widely adopted by the industry and implemented for consumers at large. In order to impart portability to the electrochemical sensors for point-of-care application, the collaboration of electrochemistry, microfluidics, electronics and communication as an interdisciplinary forum is crucial. The miniaturization, automation, IoT enabling and integration are the requirements for building the mentioned research gap. The conversion of electrochemical sensing theoretical concepts to practical applications in real time via miniaturization and integration of microfluidics will enhance this domain. In this context, of lately, several research groups have developed miniaturized microdevices as electrochemical-sensing platforms. This has led to a demand of offering a reference book as a guideline for the PhD programs in electrochemistry, MEMS, electronics and communication. Undoubtedly, this will have a huge impact for R&D in industries, public-funded research institutes and academic institutions. The book will provide a single forum to understand the current research trends and future perspectives of various electrochemical sensors and their integration in microfluidic devices, automation and point-of-care testing. For students, the book will become a motivation for them to explore these areas for their career standpoints. For the professionals, the book will become a thought-provoking stage to manoeuvre the next-generation devices/processes for commercialization.

Biosensors and Modern Biospecific Analytical Techniques further expands the Comprehensive Analytical Chemistry series' coverage of rapid analysis based on advanced technological developments. This 12-chapter volume summarizes the main developments in the biosensors field over the last 10 years. It provides a comprehensive study on the different types of biosensors, including DNA-based, enzymatic, optical, self-assembled monolayers and the third generation of biosensors. As well as many technological developments on bioanalytical microsystems and new materials for biosensors, antibody and immunoassay developments have a prominent place in the book.* Provides a comprehensive study on the different types of biosensors* Applications covered include environmental analysis, bioprocess monitoring and biomedicine* An indispensable resource for those working in analytical chemistry

This book reviews applications of nanomaterial and nanodevices in the food industry. It also discusses the advanced bioanalytical techniques, including Enzyme-Linked Immunosorbent Assay (ELISA), immunoanalytical techniques, and monoclonal antibody-based immunological techniques for detecting food adulterations and allergens. It comprehensively covers electrode modification and nano-engineered fabrication of biosensors to enhance their functionalities for utilization in food industries. The book highlights the utilization of nanobiosensors for food safety and quality analysis, such as detection of toxin, food-borne pathogen, allergen, evaluation of toxicity etc. Further, it also summarizes the recent advances in nanodevices such as nano-systems, nano-emulsions, nanopesticides, and nanocapsules and their applications in the food industry. Lastly, it covers nanomaterial-based sensors for drug analysis in diverse matrices. It serves as an invaluable source of information for professionals, researchers, academicians, and students related to food science and technology.

The increasing demand in home and industry for electronic devices has encouraged designers and researchers to investigate new devices and circuits using new materials that can perform several tasks efficiently with low IC (integrated circuit) area and low power consumption. Furthermore, the increasing demand for portable devices intensifies the search to design sensor elements, an efficient storage cell, and large-capacity memory elements. Electrical and Electronic Devices, Circuits and Materials: Design and Applications will assist the development of basic concepts and fundamentals behind devices, circuits, materials, and systems. This book will allow its readers to develop their understanding of new materials to improve device performance with even smaller dimensions and lower costs. Additionally, this book covers major challenges in MEMS (micro-electromechanical system)-based device and thin-film fabrication and characterization, including their applications in different fields such as sensors, actuators, and biomedical engineering. Key Features: Assists researchers working on devices and circuits to correlate their work with other requirements of advanced electronic systems. Offers guidance for application-oriented electrical and electronic device and circuit design for future energy-efficient systems. Encourages awareness of the international standards for electrical and electronic device and circuit design. Organized into 23 chapters, Electrical and Electronic Devices, Circuits and Materials: Design and Applications will create a foundation to generate new electrical and electronic devices and their applications. It will be of vital significance for students and researchers seeking to establish the key parameters for future work.

This book provides detailed reviews of a range of nanostructures used in the construction of biosensors as well as the applications of these biosensor nanotechnologies in the biological, chemical, and environmental monitoring fields Biological sensing is a fundamental tool for understanding living systems, but also finds practical application in medicine, drug discovery, process control, food safety, environmental monitoring, defense, and personal security. Moreover, a deeper understanding of the bio/electronic interface leads us towards new horizons in areas such as bionics, power generation, and computing. Advances in telecommunications, expert systems, and distributed diagnostics prompt us to question the current ways we deliver healthcare, while robust industrial sensors enable new paradigms in R&D and production. Despite these advances, there is a glaring absence of suitably robust and convenient sensors for body chemistries. This book examines some of the emerging technologies that are fueling scientific discovery and underpinning new products to enhance the length and quality of our lives. The 14 chapters written by leading experts cover such topics as: ZnO and graphene microelectrode applications in biosensing Assembly of polymers/metal nanoparticles Gold nanoparticle-based electrochemical biosensors Impedimetric DNA sensing employing nanomaterials Graphene and carbon nanotube-based biosensors Computational nanochemistry study of the BFPF green fluorescent protein chromophore Biosynthesis of metal nanoparticles Bioconjugated-nanoporous gold films in electrochemical biosensors The combination of molecular imprinting and nanotechnology Principles and properties of multiferroics and ceramics

The field of plasmonics has shown extraordinary capabilities in realizing highly sensitive and accurate sensors for environmental monitoring and measurement of biological analytes. The inherent potential of such devices has led to growing interest worldwide in commercial fiber optic chemical and biosensors. Optical Sensors for Biomedical Diagnostics and Environmental Monitoring is an essential resource for students, established researchers, and industry developers in need of a reference work on both the fundamentals and latest advances in optical fiber sensor technology in biomedical diagnostics and environmental monitoring. The book includes rigorous theory and experimental techniques of surface plasmon and lossy mode resonances, as well as real-time sensing applications of resonance techniques implemented over optical fiber substrate using bulk layer and/or nanostructures as transducer and sensing layers. In addition, discussion of various design options for real-time sensors in environmental monitoring and biomedical diagnostics make the book approachable to readers from multidisciplinary fields.

Biosensors in Precision Medicine: From Fundamentals to Future Trends covers important topics regarding biomarkers, including biomarker discovery, validation, application in precision medicine, the principles of biosensors, their use in precision medicine, important analytical parameters, recent advances in bioreceptors and transduction, and more. Finally, the hottest trends of biosensors in precision medicine, including lab-on-a-chip and wearable devices, advances towards telemedicine, machine learning, artificial intelligence and the commerciality of these devices are discussed. - Provides a timely review of the state-of-the-art developments in biosensors and their applications in precision medicine - Presents an evaluation of case studies, along with real-life examples - Addresses recent trends on biosensors for precision medicine

Metal Oxides for Biomedical and Biosensor Applications gives an in-depth overview of the emerging research in the biomedical and biosensing applications of metal oxides, including optimization of their surface and bulk properties. Sections cover biomedical applications of metal oxides for use in cell cultures, antibacterial and antimicrobial treatments, dental applications, drug delivery, cancer therapy, immunotherapy, photothermal therapy, tissue engineering, and metal oxide-based biosensor development. As advanced and biofunctionalized nano/micro structured metal oxides are finding applications in microfluidics, optical sensors, electrochemical sensors, DNA-based biosensing, imaging, diagnosis and analysis, this book provides a comprehensive update on the topic. Additional sections cover research challenges, technology limitations, and future trends in metal oxides and their composites regarding their usage in biomedical applications. - Includes an overview of the important applications of metal oxides for biomedical and biosensing technologies - Addresses the relationship between material properties, such as structure, morphology, composition and performance - Reviews the design and fabrication strategies of metal oxides for use in medical and biosensing applications

Early diagnosis of cancer and other non-oncological disorders gives a significant advantage for curing the disease and improving patient's life expectancy. Recent advances in biosensor-based techniques which are designed for specific biomarkers can be exploited for early diagnosis of diseases. Biosensor Based Advanced Cancer Diagnostics covers all available biosensor-based approaches and comprehensive technologies; along with their application in diagnosis, prognosis and therapeutic management of various oncological disorders. Besides this, current challenges and future aspects of these diagnostic approaches have also been discussed. This book offers a view of recent advances and is also helpful for designing new biosensor-based technologies in the field of medical science, engineering and biomedical technology. Biosensor Based Advanced Cancer Diagnostics helps biomedical engineers, researchers, molecular biologists, oncologists and clinicians with the development of point of care devices for disease diagnostics and prognostics. It also provides information on developing user friendly, sensitive, stable, accurate, low cost and minimally invasive modalities which can be adopted from lab to clinics. This book covers in-depth knowledge of disease biomarkers that can be exploited for designing and development of a range of biosensors. The editors have summarized the potential cancer biomarkers and methodology for their detection, plus transferring the developed system to clinical application by miniaturization and required integration with microfluidic systems. - Covers design and development of advanced platforms for rapid diagnosis of cancerous biomarkers - Takes a multidisciplinary approach to sensitive transducers development, nano-enabled advanced imaging, miniaturized analytical systems, and device packaging for point-of-care applications - Offers an insight into how to develop cost-effective diagnostics for early detection of cancer