* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others. The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations. FEATURES NEW chapter on neuroinflammation All chemical structure illustrations have been redrawn and improved Fully updated to reflect the latest breakthroughs and new drugs The most well-written and easily understood work on the subject More than 300 full-color illustrations!

* The most up-to-date and comprehensive coverage of the relationship of brain function and neuroactive chemicals * Authors are world-known leaders in the field * Molecular Neuropharmacology is the hot topic in medicine

Market: Pharmacy and medical students; neuroscientists; neurologists; pharmacologists Updated edition has an attractive full-color design with more illustrations Includes numerous Fact Boxes to help reinforce learning

The definitive guide to treating neurologic and psychiatric disorders with drugs and other approaches A Doody's Core Title for 2024 & 2023! Fully updated with the latest research and drugs, Nestler, Hyman, & Malenka’s Molecular Neuropharmacology, Fourth Edition, is the leading guide to molecular neuroscience. Providing an in-depth look at the neuropharmacological fundamentals of the nervous system, it delivers the knowledge and insight you need to master the pathophysiology of neurologic and psychiatric disorders. Complete with tables, diagrams, and figures clearly illustrating the intricacies of neurochemistry and molecular neuroscience, this peerless guide reviews the effects of drug action (organized by drug category) to enhance your understanding of major disease mechanisms, and it explains the pathophysiology and neuropharmacology of all major neurologic and psychiatric disorders. Concise overviews of the effects of drugs and other treatment approaches are presented in a way that boosts your understanding and retention of critical concepts. Nestler, Hyman, & Malenka’s Molecular Neuropharmacology, Fourth Edition provides a deep dive into: General principles of neuropharmacology Nervous system function Drugs that act on neuronal and glial function Major neurotransmitter systems in the brain and spinal cord Atypical neurotransmitters, including peptides, growth factors, and cytokines Major brain and spinal cord systems at the molecular, cellular, and circuit levels in health and disease

Addiction Counseling Review: Preparing for Comprehensive, Certification, and Licensing Examinations offers a clear, readable overview of the knowledge and skills those training as alcohol or other drug counselors need to pass their final degree program, certification, and licensing examinations. It is organized into six sections: Addiction Basics, Personality Development and Drugs, Common Client Problems, Counseling Theories and Skills, Treatment Resources, and Career Issues. Each chapter includes challenging study questions that enable readers to assess their own level of understanding, including true/false, multiple choice, and provocative discussion questions. Each chapter also provides a glossary of key terms and, in addition to references, annotated suggestions for further reading and Web site exploration. This book will be a resource to which students and trainees will go on referring to long after it has helped them through their examinations. In addition, faculty and established professionals will find it a useful one-stop summary of current thinking about best practice.

TAKING IT TO THE WARD! Principles of Pathophysiology has been specifically written for local nursing and Allied Health students with the aim of clearly integrating the science of Pathophysiology with clinical practice within Australia and New Zealand. Taking a systems approach to help facilitate stronger understanding, this new Australian text is the perfect learning resource for Nursing and Allied Health students.

The Massachusetts General Hospital is widely respected as one of the world's premier psychiatric institutions. Now, preeminent authorities from MGH present the newly updated edition of Massachusetts General Hospital Comprehensive Clinical Psychiatry, a unique medical reference book that continues to simplify your access to the current clinical knowledge you need - both in print and online! It provides practical approaches to a wide variety of clinical syndromes and settings, aided by stunning graphics and hundreds of questions and answers geared to each chapter. You'll have convenient access to all the authoritative answers necessary to overcome any clinical challenge. User-friendly, highly templated organization with abundant boxed summaries, bulleted points, case histories, algorithms, references, and suggested readings. Peerless, hands-on advice from members of the esteemed MGH Department of Psychiatry helps you put today's best approaches to work for your patients. Interactive and downloadable Q&As for each chapter allow you to test your retention of the material covered. In-depth coverage of many unique areas, including Psychiatric and Substance Use Disorders in Transitioning Adolescents and Young Adults; Neuroanatomical Systems Relevant to Neuropsychiatric Disorders; Legal and Ethical Issues in Psychiatry; Military Psychiatry; and Approaches to Collaborative Care and Primary Care Psychiatry. Features full, new DSM-5 criteria; new art, tables, and key points; and new Alzheimer's Disease guidelines. Highlights recent developments in the field, such as neurotherapeutics, new psychotropics, military psychiatry, collaborative care, ensuring your knowledge is thoroughly up to date. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Here is a comprehensive overview of the drugs that act on the central and peripheral nervous systems. This volume thoroughly describes the diseases associated with the nervous system and the drugs used for their treatment while also looking at the current status of these drugs and their future potential and challenges. Divided into three sections, the book first focuses on the drugs that affect the functions of the autonomic nervous system to produce therapeutic effects. These drugs may act presynaptically by manipulating the genesis, storage, and secretion, and by blocking the action of neurotransmitters. Some drugs may trigger or impede postsynaptic receptors. Section 2 focuses on drugs that affect the central nervous system, including antianxiety drugs, sedative and hypnotic drugs, antidepressant drugs, antipsychotic drugs, antiepileptic drugs, and many more. It covers the pharmacological management of various diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and others. The last section offers explanations of neurochemical interactions with the aim to develop drugs that have beneficial effects on neurochemical imbalances. This section demonstrates models to assess the transport of drugs across the blood-brain barrier and nanomedicine to treat brain disorders. This rich compilation provides thorough and extensive research updates on the important advances in neuropharmacological drugs and drug therapy from experienced and eminent academicians, researchers, and scientists from throughout the world.

Advanced Chemical Biology The modern approach to teaching chemical biology Advanced Chemical Biology is organized around the central dogma of life, progressing from genes to proteins and higher-order cellular structures, including core application areas such as imaging, chemical genetics, activity-based protein profiling, and natural product discovery and biosynthesis. Advanced topics and applications in, e. g., microbiology, developmental biology, and neurobiology, are covered in separate sections. Every chapter is homogeneous in style and layout, consisting of a short historical introduction followed by a description of the underlying concepts and a selection of recent examples of how the concept has been turned into practice. The subdivision of the contents into core and supplemental chapters enables a flexible use in teaching, both for a one-semester and a two-semester course. Written by authors and editors coming from the leading scientific institutions that have developed the concepts and technologies for this discipline, Advanced Chemical Biology includes specific information on topics like: DNA function, synthesis and engineering, chemical approaches to genome integrity, and RNA function, synthesis, and probing Chemical approaches to transcription and RNA regulation in vivo, chemical biology of genome engineering, and peptide/protein synthesis and engineering Directed evolution for chemical biology, chemical biology of cellular metabolism, chemical biology of lipids, and protein post-translational modifications Chemical glycobiology, chemical and enzymatic modification of proteins, genetic code expansion, bio-orthogonal chemistry, and cellular imaging With its broad scope and focus on turning concepts into applications, Advanced Chemical Biology is an excellent starting point for anyone entering the field and looking for a guide to the wide range of available methods and strategies that chemical biology has to offer. With a Foreword by Nobel Laureate Carolyn Bertozzi.