Molecular Genetics And The Human Personality

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In the 1960's and 1970's, personality and mental illness were conceptualized in an intertwined psychodynamic model. Biological psychiatry for many un-weaved that model and took mental illness for psychiatry and left personality to psychology. This book brings personality back into biological psychiatry, not merely in the form of personality disorder but as part of a new intertwined molecular genetic model of personality and mental disorder. This is the beginning of a new conceptual paradigm!! This breakthrough volume marks the beginning of a new era, an era made possible by the electrifying pace of discovery and innovation in the field of molecular genetics. In fact, several types of genome maps have already been completed, and today's experts confidently predict that we will have a smooth version of the sequencing of the human genome -- which contains some 3 billion base pairs Such astounding progress helped fuel the development of this remarkable volume, the first ever to discuss the brand-new -- and often controversial -- field of molecular genetics and the human personality. Questioning, critical, and strong on methodological principles, this volume reflects the point of view of its 35 distinguished contributors -- all pioneers in this burgeoning field and themselves world-class theoreticians, empiricists, clinicians, developmentalists, and statisticians. For students of psychopathology and others bold enough to hold in abeyance their understandable misgivings about the conjunction of "molecular genetics" and "human personality," this work offers an authoritative and up-to-date introduction to the molecular genetics of human personality. The book, with its wealth of facts, conjectures, hopes, and misgivings, begins with a preface by world-renowned researcher and author Irving Gottesman. The authors masterfully guide us through Chapter 1, principles and methods; Chapter 4, animal models for personality; and Chapter 11, human intelligence as a model for personality, laying the groundwork for our appreciation of the remaining empirical findings of human personality qua personality. Many chapters (6, 7, 9, 11, and 13) emphasize the neurodevelopmental and ontogenetic aspects of personality, with a major emphasis on the receptors and transporters for the neurotransmitters dopamine and serotonin. Though these neurotransmitters are a rational starting point now, the future undoubtedly will bring many other candidate genes that today cannot even be imagined, given our ignorance of the genes involved in the prenatal development of the central nervous system. Chapter 3 provides an integrative overview of the broad autism phenotype, and as such will be of special interest to child psychiatrists. Chapters 5, 8, and 10 offer enlightening information on drug and alcohol abuse. Chapter 14 discusses variations in sexuality. Adding balance and mature perspectives on how all the chapters complement and sometimes challenge one another are Chapter 2, written by a major figure in the renaissance of the relevance to psychopathology of both genetics and personality; Chapters 15-17, informed critical appraisals citing concerns and cautions about premature applications of this information in the policy arena; and Chapter 18, a judicious contemplation by the editors themselves of this promising -- and, to some, alarming -- field. Clear and meticulously researched, this eminently satisfying work is written to introduce the subject to postgraduate students just beginning to develop their research skills, to interested psychiatric practitioners, and to informed laypersons with some scientific background.

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Genre : Medical
Author : Jonathan Benjamin
Publisher : American Psychiatric Pub
Release : 2008-08-13
File : 452 Pages
ISBN-13 : 9781585627608


Handbook Of Behavior Genetics

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This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

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Genre : Medical
Author : Yong-Kyu Kim
Publisher : Springer Science & Business Media
Release : 2009-03-25
File : 557 Pages
ISBN-13 : 9780387767277


Psychiatric Genetics And Genomics

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From reviews of the hardback:'It is timely to see such an excellent textbook... Aimed at graduate level students, this book is complex enough to be thorough, but clear with enough background to be accessible... the coverage is comprehensive and the flow logical... The text is uniformly well written and achieves a successful integration.' -The Lancet'A good introduction and reference book for professionals interested in psychiatric genetics such as psychiatrists, clinical psychologists and neuroscientists... the book you want to have on your bookshelf to look up material and obtain a complete and balanced picture of the field.' -Psychological MedicineRevised for paperback edition, with new appendicesGenetics promises to provide one of the most powerful approaches to understanding the functional pathology of the human brain. This book presents a critical review of the evidence for a genetic contribution to common psychiatric conditions and the rarer single-gene disorders that may have psychiatric presentations.The first section of the book introduces the reader to molecular biology and the techniques of molecular genetics. The coverage then moves on to consider the genetics of normal and abnormal development, followed by a look at the genetics of abnormal behaviour in adults. This section includes, amongst others, consideration of personality disorders, schizophrenia and the dementias. The final section considers the applications of the work and covers issues such as counselling and ethics, closing with a look to the future.The editors are internationally renowned figures in this field and they have invited a team of equally eminent chapter authors.Readership: Psychiatrists, clinical psychologists, geneticists, neuroscientists and neurologists

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Genre : Medical
Author : Peter McGuffin
Publisher : Oxford University Press
Release : 2004-09-23
File : 508 Pages
ISBN-13 : 0198564864


Handbook Of Clinical Psychology Volume 1

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Handbook of Clinical Psychology, Volume 1: Adults provides comprehensive coverage of the fundamentals of clinical psychological practice for adults from assessment through treatment, including the innovations of the past decade in ethics, cross cultural psychology, psychoneuroimmunology, cognitive behavioral treatment, psychopharmacology, and geropsychology.

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Genre : Psychology
Author : Michel Hersen
Publisher : John Wiley & Sons
Release : 2008-01-09
File : 937 Pages
ISBN-13 : 9780471946762


Vogel And Motulsky S Human Genetics

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The fourth edition of this classical reference book can once again be relied upon to present a cohesive and up-to-date exposition of all aspects of human and medical genetics. Human genetics has become one of the main basic sciences in medicine, and molecular genetics is increasingly becoming a major part of this field. This new edition integrates a wealth of new information - mainly describing the influence of the "molecular revolution" - including the principles of epigenetic processes which together create the phenotype of a human being. Other revisions are an improved layout, sub-division into a larger number of chapters, as well as two-colour print throughout for ease of reference, and many of the figures are now in full colour. For graduates and those already working in medical genetics.

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Genre : Medical
Author : Michael Speicher
Publisher : Springer Science & Business Media
Release : 2009-11-26
File : 1006 Pages
ISBN-13 : 9783540376545


Evolutionary And Neurocognitive Approaches To Aesthetics Creativity And The Arts

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In this book, well-known scholars describe new and exciting approaches to aesthetics, creativity and psychology of the arts, approaching these topics from a point of view that is biological or related to biology and answering new questions with new methods and theories. All known societies produce and enjoy arts such as literature, music and visual decoration or depiction. Judging from prehistoric archaeological evidence, this arose very early in human development. Furthermore, Darwin was explicit in attributing aesthetic sensitivity to lower animals. These considerations lead us to wonder whether the arts might not be evolutionarily based. Although such an evolutionary basis is not obvious on the face of it, the idea has recently elicited considerable attention. The book begins with a consideration of ten theories on the evolutionary function of specific arts such as music and literature. The theory of evolution was first drawn up in biology, but evolution is not confined to biology: genuinely evolutionary theories of sociocultural change can be formulated. That they need to be formulated is shown in several chapters that discuss regular trends in literature and scientific writings. Psychologists have recently rediscovered the obvious fact that thought and perception occur in the brain, so cognitive science moves ever closer to neuroscience. Several chapters give overviews of neurocognitive and neural network approaches to creativity and aesthetic appreciation. The book concludes with two exciting describing brain-scan research on what happens in the brain during creativity and presenting a close examination of the relationship between genetically transmitted mental disorder and creativity.

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Genre : Psychology
Author : Colin Martindale
Publisher : Routledge
Release : 2019-06-04
File : 235 Pages
ISBN-13 : 9781351844536


Neurobiology Of Exceptionality

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Nurture or nature? Biology or environment? Why are some people intelligent, or personable, or creative and others obtuse, or shy, or unimaginative? Although each human being is a unique mixture of positive and negative traits and behaviors, the question remains: What is the neurobiological basis for each individual’s makeup? For example, why does one person suffer from a disorder (e.g., ADHD, autism, mental retardation) and another lives free of maladies? These are just some of the issues addressed in detail in Neurobiology of Exceptionality. The introductory chapter provides a broad-based overview of current neurobiological techniques (i.e., terms, procedures, and technologies), which are followed by chapters that offer in-depth examination of the neurobiological bases for: • Impulsive sensation seeking • Creativity • Intelligence • Antisociality • Autism, mental retardation, and Down Syndrome • ADHD • Savant Syndrome This volume provides a one-stop source for clinical psychologists and other allied mental health professionals to access information on a wide range of research on the neurobiology of psychological and psychiatric traits. It is designed to give readers an overview of the current knowledge base of the biological processes for each trait. It is unlikely that any one book could cover all human traits, but the Neurobiology of Exceptionality addresses a wide range of exceptional psychological traits and psychiatric disorders.

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Genre : Psychology
Author : Con Stough
Publisher : Springer Science & Business Media
Release : 2006-09-28
File : 222 Pages
ISBN-13 : 9780306486494


The Trouble With Twin Studies

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The Trouble with Twin Studies questions popular genetic explanations of human behavioral differences based upon the existing body of twin research. Psychologist Jay Joseph outlines the fallacies of twin studies in the context of the ongoing decades-long failure to discover genes for human behavioral differences, including IQ, personality, and the major psychiatric disorders. This volume critically examines twin research, with a special emphasis on reared-apart twin studies, and incorporates new and updated perspectives, analyses, arguments, and evidence.

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Genre : Psychology
Author : Jay Joseph
Publisher : Routledge
Release : 2014-11-20
File : 333 Pages
ISBN-13 : 9781317605904


An Introduction To Human Molecular Genetics

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An Introduction to Human Molecular Genetics Second Edition Jack J. Pasternak The Second Edition of this internationally acclaimed text expandsits coverage of the molecular genetics of inherited human diseaseswith the latest research findings and discoveries. Using a unique,systems-based approach, the text offers readers a thoroughexplanation of the gene discovery process and how defective genesare linked to inherited disease states in major organ and tissuesystems. All the latest developments in functional genomics,proteomics, and microarray technology have been thoroughlyincorporated into the text. The first part of the text introduces readers to the fundamentalsof cytogenetics and Mendelian genetics. Next, techniques andstrategies for gene manipulation, mapping, and isolation areexamined. Readers will particularly appreciate the text'sexceptionally thorough and clear explanation of genetic mapping.The final part features unique coverage of the molecular geneticsof distinct biological systems, covering muscle, neurological, eye,cancer, and mitochondrial disorders. Throughout the text, helpfulfigures and diagrams illustrate and clarify complex material. Readers familiar with the first edition will recognize the text'ssame lucid and engaging style, and will find a wealth of new andexpanded material that brings them fully up to date with a currentunderstanding of the field, including: * New chapters on complex genetic disorders, genomic imprinting,and human population genetics * Expanded and fully revised section on clinical genetics, coveringdiagnostic testing, molecular screening, and varioustreatments This text is targeted at upper-level undergraduate students,graduate students, and medical students. It is also an excellentreference for researchers and physicians who need a clinicallyrelevant reference for the molecular genetics of inherited humandiseases.

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Genre : Science
Author : Jack J. Pasternak
Publisher : John Wiley & Sons
Release : 2005-06-14
File : 656 Pages
ISBN-13 : 9780471719175


Handbook Of Social Psychology Volume 1

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First published in 1935, The Handbook of Social Psychology was the first major reference work to cover the field of social psychology. The field has since evolved and expanded tremendously, and in each subsequent edition, The Handbook of Social Psychology is still the foremost reference that academics, researchers, and graduate students in psychology turn to for the most current, well-researched, and thorough information covering the field of social psychology. This volume of the Fifth Edition covers the science of social psychology and the social being.

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Genre : Psychology
Author : Susan T. Fiske
Publisher : John Wiley & Sons
Release : 2010-02-15
File : 899 Pages
ISBN-13 : 9780470137482