Ten articles provide an overview of the recently flowering research into the genetics and molecular biology of fungus species that are economically significant in industry. The contributors, from a variety of disciplines, report on work in such areas as industrial enzymes, antibiotics, toxins, heter

Several excellent books have been published that address one or more aspects of the diverse field of industrial mycology, but none of them cover the entire process of fungal bioactive metabolites discovery. Until now. The Handbook of Industrial Mycology provides, in one volume, an overview of recent developments in industrial mycology with emphasis on the discovery of bioactive metabolites and, most importantly, their underlying biology and genetics. Two additional features distinguish this book from other books in the field: 1) most chapters are prepared using experimental data to illustrate theories and 2) the authors provide methodologies and experimental protocols in their chapters. Presenting a comprehensive overview of recent advances, the book provides a framework of basic methods, tools, and organizational principles for channeling fungal germplasm into the academic, pharmaceutical, and enzyme discovery laboratories. It covers the complex range of processes involved in the discovery, characterization, and profiling of bioactive fungal metabolites. The book includes examples of several recently marketed fungal metabolites and explores the impact of fungi on applications in the pharmaceutical, food and beverage, agricultural, and agrochemical industries.

Frontiers of Industrial Mycology describes the present efforts underway to create a broad range of large-scale applications using filamentous fungi. Important and environmentally sound applications currently being developed include the use of fungi for novel *B-lactams in antibiotic production, biobleaching and the bioconversion of wood pulp, agricultural biotechnology for creating biological insecticides and herbicides, food fermentations, and the commercial raising of shiitake mushrooms, a growing and largely untapped market in North America. The topics discussed in this volume are on the cutting edge of industrial mycology. This book will thus benefit a wide range of professionals and academics in biotechnology, mycology, microbiology, plant science, entomology, and biochemistry.

Describing the scientific and commercial applications of microbial recombinant DNA technology, this outstanding, single-source reference offers state-of-the-art reviews of gene expression in the most important classes of recombinant microorganisms-providing numerous examples of the expression of homologous genes or heterologous gene products. Presents a unique collection of safety and regulatory considerations from around the world and addresses specific measures to be taken for large-scale industrial operations!

For millennia, the presence of fungi in food has been both boon and bane to food stores. Fungi can spoil large quantities of food and produce dangerous toxins that threaten human health; however, fungal spoilage in certain foods can produce a unique, highly prized food source and there are some very effective fungal derived medicines. A thorough un

Bridging the gap between laboratory observations and industrial practices, this work presents detailed information on recombinant micro-organisms and their applications in industry and agriculture. All recombinant microbes, bacteria, yeasts and fungi are covered.

This book is about the growth and differentiation processes underlying the growth and differentia of filamentous fungi. The impetus for this work tion of fungi and that it provides the reader with stems from our perception that the coverage of adequate source references for further information. this highly diverse and important group of organ It is estimated conservatively that there are more isms has been neglected in recent years, despite than 1. 5 million species of fungi - more than five many significant advances in our understanding of times the number of vascular plants and second the underlying mechanisms of growth. This situ only in diversity to the insects. The extreme ation contrasts with the treatment of Saccharomyces diversity of form in the fungi has always been a cerevisiae, for example, which because of its ideal source of inspiration for mycologists. This book is properties for genetic analyses, has established concerned mainly with those systems that have itself as the model eukaryote for the analysis of the been well characterized from the biochemical, cell cycle, and basic studies of biochemical and physiological or genetic points of view. Although genetic regulation. This book does not deal with it has not been possible to illustrate the breadth of the detailed growth phYSiology of S.

Fungi are now at the forefront of research on mechanisms in gene silencing, biological rhythm, mating processes, biogenesis of intracellular organelles, adaptations to hostile habitats, structure of natural populations, and speciation. Because of their small genomes, fungi are being used in "systems biology" to understand the connections between ge

Over the past fifty years plant breeders have achieved impressive improvements in yield, quality and disease resistance. These gains suggest that many more modifications might be introduced if appropriate genes can be identified. Current DNA techniques allow the construction of transgenic plants and this important new book reviews the current state of knowledge. A team of leading researchers provide in-depth reviews at the cutting edge of technology for laboratory techniques for the transformation of important soil microorganisms and recalcitrant plants of economic value. The book is divided into three sections: soil microorganisms; cereal crops; and industrially important plants. The most effective methods used to date are compared, and their merits and limitations discussed. Some chapters emphasise case studies and applications. In cases where obstacles remain to be overcome, an overview of progress to date is given. The book will serve as a general guide and reference tool for those working on transformation in microbiology and plant science.

It was not until recent years that the study of polyamines, their mechanisms of synthesis, and the roles they play in metabolism have flourished, becoming a fertile field of intense research. Polyamines in Fungi: Their Distribution, Metabolism, and Role in Cell Differentiation and Morphogenesis provides a complete overview of its topic. It is the f