Nanomedicine in Cancer Immunotherapy bridges the two disciplines of nanotechnology and immunology, summarizing the latest research into novel cancer treatments, often personalized to the patient.This book covers a wide range of nanomaterial types for use in cancer immunotherapy, including hydrogel, lipid, exosome, gold and peptide nanoparticles. The preparation, application, pros and cons of each nanomaterial class is reviewed, helping the reader understand the potential for each and tailor their selection to their needs. Nanovaccines are also covered, along with a clinical evaluation and market analysis of nanomedicines for immunotherapy, offering an important clinical and commercial overview of this rapidly developing field.Nanomedicine in Cancer Immunotherapy is an interesting reference for those working in the fields of nanotechnology, immunology and cancer therapeutics, as well as clinicians with an interest in novel nano-based cancer treatments. - Provides a single source for a review of the latest research in the development of nanomaterials for cancer immunotherapy - Introduces the reader to basic principles of immunology and immunotherapy to aid our understanding - Details a wide range of nanomaterial classes for cancer immunotherapy, with advantages and disadvantages thoroughly analyzed

The book covers the latest developments in biologically-inspired and derived nanomedicine for cancer therapy. The purpose of the book is to illustrate the significance of naturally-mimicking systems for enhancing the dose delivered to the tumor, to improve stability, and prolong the circulation time. Moreover, readers are presented with advanced materials such as adjuvants for immunostimulation in cancer vaccines. The book also provides a comprehensive overview of the current status of academic research. This is an ideal book for students, researchers, and professors working in nanotechnology, cancer, targeted drug delivery, controlled drug release, materials science, and biomaterials as well as companies developing cancer immunotherapy.

Chapter 1: Cancer biology Chapter 2: Histone deacetylase inhibitors Chapter 3: Nanomedicine based cancer treatments: Abraxane Chapter 4: Nanomedicine based cancer treatments: Doxil

The collection is diverse in the topics covered as well as the contributors, who come from across the globe. The overall topic is inherently a complex one since it integrates the exceptional complexity of cancer biology and treatment with the large and rapidly growing number of potential nanostructures and modifications that could be applied to treatment. In both cancer and nanotechnology, a very small change of a relevant variable can generate exceptional variability in biological outcome, creating inherent challenges to clinical adoption. As with many high-potential fields in medicine, the recognition of exceptional potential for nanotechnology in cancer therapy, with associated expectations of rapid clinical impact, has been followed by disappointingly slow progress that highlights not failure but rather unrealistic expectations for rapid progress. We have passed that period of expected rapid clinical impact for nanoparticle treatment of cancer and are now well-entrenched in the more realistic phase of exploiting the easiest applications, in this case packaging of established chemotherapy drugs, while carefully studying the exceptional numbers of relevant variables that must be evaluated for efficacy and safety of innovative strategies. Although never as rapid as hoped, the progress is clear and clinical impact is growing.

This book reviews the current applications and future prospects of nanomaterials in cancer diagnostics and therapy. Nanomaterials have recently emerged as a remarkable and promising tool for cancer therapy and diagnosis, due to their broad range of intrinsic molecular properties. To overcome the current limitations of nanoparticles in drug delivery systems, attempts have been made to synthesize nanoparticles from biological materials for targeted cancer therapy. This book provides concise evaluations of various potential bio-inspired platforms that mimic natural components of the body and offer effective and versatile drug delivery systems for cancer therapy. It also assesses the potential of nanoparticles to enhance the outcomes of cancer immunotherapy via immune cell activation and tumor microenvironment modulation. The book also summarizes in the applications of nanomaterials for the detection, prevention, and treatment of solid tumors and in the treatment of leukemia and lymphomas. In closing, it discusses ethical issues in nanomedicine, including risk assessment, risk management, and risk communication during clinical trials. The book offers offers a valuable source of information for students, academics, researchers, scientists, clinicians, and healthcare professionals working in nanotechnology and cancer research.

Recent advances in nanomedicine offer ground-breaking methods for the prevention, diagnosis and treatment of some fatal diseases. Amongst the most promising nanomaterials being developed are magnetic nanomaterials, including magnetic nanoparticles and magnetic nanosensors. Some nanomagnetic medical applications are already commercially available with more set to be released over the coming years. Nanomedicine, Design and Applications of Magnetic Nanomaterials, Nanosensors and Nanosystems presents a comprehensive overview of the biomedical applications of various types of functional magnetic materials. The book provides an introduction to magnetic nanomaterials before systematically discussing the individual materials, their physical and chemical principles, fabrication techniques and biomedical applications. This methodical approach allows this book to be used both as a textbook for beginners to the subject and as a convenient reference for professionals in the field. Discusses magnetic nanoparticles including nanowires, nanotubes, zero-dimensional nanosperes and naturally existing magnetosomes. Examines intrinsically smart magnetic materials and describes their part in the development of biomedical sensors and biochips, which are often used in biomedical tests. Integrates the research efforts of different disciplines – from materials sciences to biology and electrical engineering to medicine – in order to provide a unified and authoritative guide to a richly interdisciplinary field. This volume is of great appeal to students and researchers in the fields of electrical and electronic engineering, biomedical engineering, nanotechnology, materials science, physics, medicine and biology. It is also of interest to practising engineers, materials scientists, chemists and research medical doctors involved in the development of magnetic materials and structures for biomedical applications.

Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases takes a scientific approach to nanotechnology and nanomaterials applications in medicine, while also explaining the core biological principles for an audience of biomedical engineers, materials scientists, pharmacologists, and medical diagnostic technicians. The book is structured by major disease groups, offering a practical, application-based focus for scientists, engineers, and clinicians alike. The spectrum of medical applications is explored, from diagnostics and imaging to drug delivery, monitoring, therapies, and disease prevention. It also focuses specifically on the synthesis of nanomaterials and their potential health risks (particularly toxicity). Nanomedicine — the application of nanomaterials and devices for addressing medical problems — has demonstrated great potential for enabling improved diagnosis, treatment, and monitoring of many serious illnesses, including cancer, cardiovascular and neurological disorders, HIV/AIDS, and diabetes, as well as many types of inflammatory and infectious diseases. - Gain an understanding of how nanotechnologies and nanomaterials can be deployed in the fight against the major life-threatening diseases: cancer, neurological disorders (including Alzheimer's and Parkinson's), cardiovascular diseases, and HIV/AIDS - Discover the latest developments in nanomedicine, from therapies and drug delivery to diagnostics and disease prevention - The authors cover the health risks of nanomaterials as well as their benefits, considering toxicity and potential carcinogens

A comprehensive and multidisciplinary guide to nanomaterials-based medicine Nanomedicine is the study and application of nanomaterials-based medical techniques. In recent years it has very rapidly become indispensable in a huge range of medical contexts, from analysis of extreme life events to diagnosis and treatment of life-threatening intractable diseases, such as cancers and cardiovascular diseases. It has already transformed both research and clinical outcomes in many areas of medicine and promises to continue as the cutting-edge research and clinical area for the next generation of medical specialists. Nanomedicine: Fundamentals, Synthesis, and Applications constitutes a comprehensive guide to this subfield and its recent advances. Beginning with a brief history of the field and introduction to its core principles, it thoroughly treats recent developments in this vital and ever-growing field. Its multidisciplinary approach equips the reader with a systematic overview of these life-saving developments in medicine. Nanomedicine readers will also find: Edited by a leading researcher with decades of experience in both North America and China Detailed treatment of subjects including nanocarriers, nanomaterial bioprobes, multi-function nanodrugs, nanomedicine-mediated immunotherapy and/or physical ablation, and more A comprehensive volume treats every facet of the subject Nanomedicine is a vital resource for biochemists, biomedical engineers, pharmaceutical chemists, physicists, and professionals in the biotechnological industries, as well as for clinicians looking to familiarize themselves with nanomedical techniques and instrumentation.

Nanotechnology in Human Health: Current Research and Future Trends details the various challenges faced in human healthcare settings and how nanotechnology can be used to target and improve outcomes. The book describes the application of nanoparticles in the diagnosis of human diseases, including metabolic diseases, cancer, bacterial infection, organ degeneration and the various targeted, nano-based treatments available. Several chapters look at how microbial biofilms - a key clinical concern - can be mitigated using nanomaterials and nanotechnology. In addition, the book covers how different nanoparticle types can be utilized as therapeutic agents. This book combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary reference for materials scientists, microbiologists, biomedical engineers and clinicians with an interest in nanotechnology. - Reviews the potential applications of nanotechnology in healthcare, with a focus on combating antibiotic-resistant microbial infections and biofilms - Explores the legal, social and ethical challenges of utilizing nanotechnology in clinical settings - Combines materials science concepts and techniques with clinical insights and understanding to provide an interdisciplinary approach