Nanotechnology for Biomedical Imaging and Diagnostics: From Nanoparticle Design to Clinical Applications reflects upon the increasing role of nanomaterials in biological and medical imaging, presenting a thorough description of current research as well as future directions. With contributions from experts in nanotechnology and imaging from academia, industry, and healthcare, this book provides a comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology and bioimaging Provides comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine Written by well-recognized experts in academia, industry, and healthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research and diagnostic topics, this book will appeal to students, scientiests, and healthcare professionals alike

The rapid progress of nanoscience and the application of nanotechnology in medicine are changing the foundations of disease prevention, diagnosis and treatment. At the core of nanotechnology for modern biomedical imaging and interventions, nano/microparticles offer 3-in-1 primary functions as imaging agents, target-specific probes, and target-specific therapeutic carriers. Nanoparticle-based imaging and interventions have already exhibited exciting potential in probing the bases or roots of diseases, such as to identify their altered molecular profiles and/or cellular characteristics prior to the appearance of visual anatomic alterations. As nanoparticle-based imaging and interventions continue to be refined and are increasingly applied to clinical practice, they will certainly have significant impact on global health care in the near future. Scientists from various disciplines around the world have already done outstanding work in developing various nanotechnology-based imaging modalities, such as molecular and cellular imaging with X-ray-based computerised tomography (CT), ultrasound, magnetic resonance (MR), optics, and nuclear medicine.However, clinical applications of these particle-based imaging techniques are still very limited. This can be attributed to a gap existing between basic science and clinical practice, where scientists have no direct access to patient care; meanwhile clinicians are extremely busy with their daily clinical practices and lack the time or means to learn such new technological evolutions. In order to bring the two parties together, a bridge needs to be built between basic science and clinical practice, as termed translational medicine by the US National Institute of Health (NIH). The aim of writing this book is to facilitate such translation of nanotechnology-based imaging modalities from laboratory benches to clinical practices. The authors come from several continents around the world, and are experts working in the fields of nanotechnology, material science, biomedical engineering, medicine, pathology, medical imaging, and interventional radiology. We hope this book will provoke common interest, brainstorming and co-operation among professionals in both technology and medicine, and will bring nanomedicine one step closer to improving patient care.

The rapid progress of nanoscience and the application of nanotechnology in medicine are changing the foundations of disease prevention, diagnosis and treatment. At the core of nanotechnology for modern biomedical imaging and interventions, nano/microparticles offer "3-in-1" primary functions as imaging agents, target-specific probes, and target-specific therapeutic carriers. Nanoparticle-based imaging and interventions have already exhibited exciting potential in probing the bases or "roots" of diseases, such as to identify their altered molecular profiles and/or cellular characteristics prior to the appearance of visual anatomic alterations. As nanoparticle-based imaging and interventions continue to be refined and are increasingly applied to clinical practice, they will certainly have significant impact on global health care in the near future. Scientists from various disciplines around the world have already done outstanding work in developing various nanotechnology-based imaging modalities, such as molecular and cellular imaging with X-ray-based computerized tomography (CT), ultrasound, magnetic resonance (MR), optics, and nuclear medicine. However, clinical applications of these particle-based imaging techniques are still very limited. This can be attributed to a gap existing between basic science and clinical practice, where scientists have no direct access to patient care; meanwhile clinicians are extremely busy with their daily clinical practices and lack the time or means to learn such new technological evolutions. In order to bring the two parties together, a bridge needs to be built between basic science and clinical practice, as termed "translational medicine" by the US National Institute of Health (NIH). The aim of writing this book is to facilitate such translation of nanotechnology-based imaging modalities from laboratory benches to clinical practices. The authors come from several continents around the world, and are experts working in the fields of nanotechnology, material science, biomedical engineering, medicine, pathology, medical imaging, and interventional radiology. We hope this book will provoke common interest, brainstorming and cooperation among professionals in both technology and medicine, and will bring nanomedicine one step closer to improving patient care.

Nanotechnology for Biomedical Imaging and Diagnostics: From Nanoparticle Design to Clinical Applications reflects upon the increasing role of nanomaterials in biological and medical imaging, presenting a thorough description of current research as well as future directions. With contributions from experts in nanotechnology and imaging from academia, industry, and healthcare, this book provides a comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine. Grouped into three sections, the book: Elucidates all major aspects of nanotechnology and bioimaging Provides comprehensive coverage of the field, ranging from the architectural design of nanomaterials to their broad imaging applications in medicine Written by well-recognized experts in academia, industry, and healthcare, will be an excellence source of reference With a multidisciplinary approach and a balance of research and diagnostic topics, this book will appeal to students, scientiests, and healthcare professionals alike

The current generation of imaging nanoparticles is diverse and dependent on its myriad of applications. This book provides an overview of how these imaging particles can be designed to fulfill specific requirements for applications across different imaging modalities. It presents, for the first time, a comprehensive interdisciplinary overview of the impact nanoparticles have on biomedical imaging and is a common central resource for researchers and teachers.

This book covers the most recent advances in using nanoparticles for biomedical imaging, including magnetic resonance imaging (MRI), magnetic particle imaging (MPI), nuclear medicine, ultrasound (US) imaging, computed tomography (CT), and optical imaging. Topics include nanoparticles for MRI and MPI, siRNA delivery, theranostic nanoparticles for PET imaging of drug delivery, US nanoparticles for imaging drug delivery, inorganic nanoparticles for targeted CT imaging, and quantum dots for optical imaging. This book serves as a valuable resource for the fundamental science of diagnostic nanoparticles and their interactions with biological targets, providing a practical handbook for improved detection of disease and its clinical implementation.

This comprehensive volume provides the reader valuable insight into the major areas of biomedical nanomaterials, advanced nanomedicine, nanotheragnostics, and cutting-edge nanoscaffolds. The ability to control the structure of materials allows scientists to accomplish what once appeared impossible before the advent of nanotechnology. It is now possible to generate nanoscopic self-assembled and self-destructive robots for effective utilization in therapeutics, diagnostics, and biomedical implants. Nanoscopic therapeutic systems incorporate therapeutic agents, molecular targeting, and diagnostic imaging capabilities and they have emerged as the next generation of multifarious nanomedicine to improve the therapeutic outcome including chemo and translational therapy. Nanomaterials in Drug Delivery, Imaging, and Tissue Engineering comprises fifteen chapters authored by senior scientists, and is one of the first books to cover nanotheragnostics, which is the new developmental edge of nanomedicine combining both diagnostic and therapeutic elements at the nano level. This large multidisciplinary reference work has four main parts: biomedical nanomaterials; advanced nanomedicine; nanotheragnostics; and nanoscaffolds technology. This groundbreaking volume also covers: Multifunctional polymeric nanostructures for therapy and diagnosis Metalla-assemblies acting as drug carriers Nanomaterials for management of lung disorders and drug delivery Responsive polymer-inorganic hybrid nanogels for optical sensing, imaging, and drug delivery Core/shell nanoparticles for drug delivery and diagnosis Theranostic nanoparticles for cancer imaging and therapy Magnetic nanoparticles in tissue regeneration Core-sheath fibers for regenerative medicine

This book comprehensively reviews the recent advances in nanomaterial-based molecular imaging, diagnostics, and personalized therapy. It discusses the novel biocompatible fluorescent nanomaterials, their synthesis, and modern state of art characterization, as well as the various strategies for immobilization of biomacromolecules on the nanomaterial surface and approaches for increasing their stability. In addition, the book describes the synthesis of lectin nanoconjugates using different types of biocompatible raw materials and their systematic characterization. Lastly, it presents our current understanding of the biomolecular carona, which affects nanoparticle-based targeted drug delivery, and examines the conceptual approaches to improve the in-vivo efficacy of targeted drug delivery.

Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques. The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. - A valuable resource for researchers, practitioners and students working in biomedical, biotechnological and engineering fields - A detailed guide to recent scientific progress, along with the latest application methods - Presents innovative opportunities and ideas for developing or improving technologies in nanomedicine and medical imaging

The title "Nano Biotechnology for Biomedical and Diagnostics Research" will address research aspects related to nanomaterial in imaging and biological research, nanomaterials as a biosensing tool, DNA nanotechnology, nanomaterials for drug delivery, medicinal and therapeutic application and cytotoxicity of nanomaterials. These topics will be covered by 16 different manuscripts. Amongst the authors that will contribute to the book are major scientific leaders such as S. Weiss - UCLA, I. Willner, and G. Golomb – HUJI, S. Esener - UCSD, E.C. Simmel - Tech. Univ. Munchen, I. Medintz – NRL, N. Hildebrandt - Université Paris and more. The manuscripts in the book intend to present specifically biological, diagnostics and medical problems with their potential solution by nano technology or materials. In this respect this book is unique, since it would arise from the biological problems to the nano technology possible solution and not vice versa.