This book aims to summarize the latest research progress of biomedical nanozymes in diagnostic and therapeutic related fields. In terms of diagnostics, it will cover in vitro diagnostics, live analysis, and some emerging bioanalysis. In terms of therapeutics, it will introduce antioxidant therapy, peroxidation therapy and emerging therapy respectively. Furthermore, the research results previously scattered in many journals and conferences worldwide are methodically edited and presented in a unified form. Based on the new ideas and developments presented in this book, it will be of interest to readers from different areas, such as chemistry, materials, nanoscience and nanotechnology, biomedical and clinical studies, etc.

This book presents the state-of-the-art advances and applications of nanozymes, the recently developing branch of enzymology that synthesizes and uses nanomaterials that mimic the function of traditional enzymes. During the past decade, the study of nanozymes has grown rapidly. Several new nanomaterials that exhibit enzymatic actions have been identified, along with new applications for their practical use. This book draws upon the work of experts from around the world and provides an in-depth analysis and cutting-edge overview of nanozymes, with an eye toward their present and future applications. Chapters are arranged in a logical order to provide physio-chemical characterization of nanozyme and basic mechanisms of their enzymatic actions. Focusing on current limitations of nanozymes and their reaction kinetics, the book presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. It also focuses on traditional and novel nanozyme applications, such as biosensing, drug delivery, and disease therapy, as well as their use as antibacterials. An important addition in this book is the summary of emerging literature on nanozyme toxicology. This book is intended as a ready reference for advanced undergraduate and graduate students doing research in nanotechnology; materials science; chemistry; and chemical, biological, biomedical, and food engineering. Research and development scientists, engineers, and technologists working in the chemical and biological/biomedical industries will gain much from the materials in this book for their industry practice. Presents a comprehensive discourse on nanozyme engineering that includes possible surface modifications to enhance nanozyme effectiveness. Discusses metal organic frameworks as nanozymes. Reviews on traditional and novel nanozyme applications, such as biosensing, drug delivery, disease therapy, and their use as antibacterials. Examines nanozyme toxicology. Dr. Sundaram Gunasekaran is a Professor in the Department of Biological Systems Engineering at the University of Wisconsin–Madison.

This book introduces the new concept of “nanozyme”, which refers to nanomaterials with intrinsic enzymatic activity, rather than nanomaterials with biological enzymes incorporated on the surface. The book presents the cutting-edge advances in nanozyme, with emphasis on state-of-the-art applications in many important fields, such as in the biomedical fields and for environmental protection. The nanozyme is a totally new type of artificial enzyme and exhibits huge advantages over natural enzymes, including greater stability, low cost, versatility, simplicity, and suitability for industry. It is of interest to university researchers, R&D engineers, as well as graduate students in nanoscience and technology, and biology wishing to learn the core principles, methods, and the corresponding applications of “nanozyme”.

Reactions catalyzed by metalloenzymes have great potential for applications in the biotechnology and pharmaceutical industries. While only a few of these enzymes have yet been used in such applications, in the last few decades numerous efficient, selective, environmentally friendly and economical synthetic analogues have been described, including supramolecular, polymeric, nanoparticulate and lowmolecular- weight organometallic complexes, and metal organic frameworks. In this Research Topic, we present a collection of original research and review articles that show significant recent advances made in the rational design of such artificial metalloenzymes.

This book presents a collection of chapters on modern bioelectrochemistry, showing different aspects of emerging techniques and materials, biodevice design and reactions. The chapters provide relevant bibliographic information for researchers and students interested in electrochemical impedance spectroscopy applied in biodevices, trends, and validation on impedimetric immunosensors in the application of routine analysis, electrochemical–surface plasmon bioanalytics and carbon nanomaterials in electrochemical biodevices, insights on inorganic complexes and metal based for biomarkers sensors, bioelectrodes and cascade reactions and field effect-based reactions.

This book summarizes nanotechnology-based agricultural research for crop productivity and the management of various plant pathogens. It deals with the application of nano-molecules for quick, cost-effective, and precise plant disease diagnostic procedures, plant pests and disease management, nano-pesticides, and nano-diagnostics. Further, it explains nanomaterials for biotic stress management, with an insight into the synthesis and modification of nanomaterials and their potential applications in different domains for disease management. Features include: Compilation of current research on the Nanomaterials as well as their versatile applications in plant biotic stress management Description of the role of nanomaterials as enzyme-mimicking nanoparticles, nano-pesticides, nano-fertilizers, and nanomaterials Review of day-to-day problems related to crop plants, their diagnostics, and stress management Exploration of trends in nanomaterial utility in diagnostics, enzyme-mimicking, and crop protection, and their possible role in plant disease management Study of pertinent nanomaterials including synthetic strategies, properties, chemistry, and applications This book is aimed at researchers and graduate students in plant pathology, genetic engineering, environmental science, botany, bioengineering, and nanotechnology.

This book reviews the latest developments and applications of nanozymes in environmental science. Protection of the environment is essential because pollution has become a global problem with many adverse effects on life and ecosystems. For that, remediation strategies and techniques have been designed, yet they are limited. Here, the recent development of nanotechnology opens a new vista for environmental remediation. In particular, nanomaterials displaying enzyme-like activities, named ‘nanozymes’, appear very promising for environmental monitoring, contaminant detection, microbial management, and degradation of organic pollutants. Nanomaterials including metallic, metal oxides and carbon-based nanoparticles with nanozymes activities have been synthesized. These nanozymes have similar activities as natural peroxidase, oxidase, superoxide dismutase and catalase enzymes. Nanozymes have several advantages, yet they suffer from several limitations such as low catalytic efficiency, less substrate selectivity, biocompatibility, and lack of engineering of the active sites.

The field of nanoscience continues to grow and, with such a vast landscape of material, careful distillation of the most important discoveries will help researchers find the key information they require. Nanoscience provides a critical and comprehensive assessment of the most recent research and opinion from across the globe. Topics covered in this volume include 2D materials for Li-ion batteries, porous organic polymers as an emerging platform for photocatalytic water splitting, smart materials for gas detection and monitoring and redox enzyme-mimicking nanomaterials. Covering energy, biological and nanomaterials applications, this volume appeals to anyone practising in nano-allied fields, or wishing to enter the nano-world. Readers will benefit from this resource as they are presented with the current thought and applications of nanoscience.

Nanoscience Volume 7 provides a critical and comprehensive assessment of the most recent research and opinion from across the globe for anyone practising in any nano-allied field, or wishing to enter the nano-world.