Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma. Contains contributions by international authors Covers recent clinical trial advancements and findings and updates on ongoing trials Presents an overview of clinical practice guidelines for the management of traumatic spinal cord injury featured Provides the reader with insights regarding the translation of research from bench to bedside and the skills needed to understand the translational pathway using real-life examples

Therapeutic approaches in spinal cord injury.- Cell death and tissue degeneration in traumatic brain injury.- neurotransmitters and electrophysiology in brain injury.- neurotransmitters and electrophysiology in brain injury.- Parkinsonism in the MPTP model.- EAE Demyelination.- EAE Neurodegeneration.- Cataract.- Uveitis.- Optic neuritis.- GBS/peripherial neuropathy, paraproteinemia.- Brain Tumor(Tumor Mechanisma).- Brain Tumor and angiogenesis.- SCIDS.- Phenylketone urea and mental retardation.- Neurofibromatosis.- BBB.- Muscular dystrophy.- Stracher.- Diabetic neuropathy/retinopathy/cataract.- Peroxisomes and adrenoleukodystrophy ALD.- Neuroprotection.- NFkB (Inflammation and spinal cord injury).- spinal cord injury and traumatic brain injury.- free radicals and neuroprotection.- Traumatic brain injury.- white matter degeneration.- Mitochondrial membrane defects.- Encephalomyopathies.- metal induced neurodegenaration.- neurometals in protein misfolding neurodegenerative diseases.- hyperammonemia.- kyneurenines in the brain preclinical and clinical studies, therapeutic condiserations.

This volume offers every clinical ophthalmologist valuable guidance in implementing the results of the latest multicenter clinical trials in practice. Chapters on all major disease entities review all pertinent trials, bring these trials into a real-world setting, and show how the results should influence day-to-day patient management. Coverage includes diseases in all ophthalmologic subspecialties—cornea/external disease, glaucoma, retina, pediatric ophthalmology, ocular oncology, neuro-ophthalmology, and oculoplastics. More than 170 illustrations, 92 in full color, complement the text. General ophthalmologists will have at their fingertips, in an easily digestible format, the current standard of patient care across the spectrum of ophthalmology.

Clinical Neuroepidemiology of Acute and Chronic Disorders explores the epidemiology of disorders that affect the nervous system, providing comprehensive discussions on incidence, prevalence, and more. With thorough coverage of a variety of disorders, chapters detail etiology, risk factors, pathophysiology, clinical manifestations, diagnosis, global incidence and prevalence, age-specific incidence, global mortality, prevention, treatment and prognosis for each disorder. Chapters uniquely discuss the effects of the COVID-19 coronavirus upon the nervous system and in relation to several diseases, including new discoveries and treatments for Alzheimer's disease and migraine headaches. Real-world case studies with critical thinking questions and "Focus On" boxes highlight important information. - Covers a variety of disorders and their etiology, including risk factors, pathophysiology clinical manifestations diagnosis, incidence of mortality, prevention, treatment and prognosis - Features real-world case studies with critical thinking questions and answers - Includes Focus On boxes that highlight key information in each chapter - Highlights treatments for various disorders, including Alzheimer's disease and migraines - Discusses the effects of COVID-19 on the nervous system in relation to several diseases

This book provide useful information in the area of spinal infections, particularly with regard to those that receive delayed treatment. The book first deals with various spinal infections and their manifestations. It is strong in the areas of tuberculosis and the structural problems that ensue when spinal infections are not diagnosed and treated early. Structural diagrams are helpful. Apart from surgical techniques, adequate emphasis has been laid on clinical features, value of modern diagnostic facilities and appropriate drug therapy. This book will be a useful reference book with more infor.

The Spine: Medical and Surgical Conditions is a complete, two volume, evidence based study edited by an internationally recognised team of spine surgeons based in the USA, China, Canada, Germany, Japan, Brazil, Egypt and India. The two volumes are divided into 137 chapters, across fourteen sections. The first section covers general topics in spinal medicine, including anatomy, biomechanics, physical and neurological examination, interventional diagnostics and therapeutics, and anaesthesia. This is followed by sections on the development of the spine, metabolic disorders, and bone grafting. Subsequent sections focus on surgery for particular parts of the spine, including cervical, lumbar and thoracic, as well as sections on spinal cord injuries and motor preservation. Later sections in the book provide information on the spine in paediatrics, adult deformity, tumours, vascular malformations and infections, complications of spinal surgery, and a final section on minimally invasive techniques. Enhanced by 1500 full colour images, The Spine: Medical and Surgical Conditions is also made available online, complete with text, images and video, with each physical copy. Key Points Comprehensive, two volume guide to spinal medicine Covers anatomy, biomechanics, examination, diagnostics, therapeutics, anaesthesia, surgery and complications Enhanced by 1500 full colour images Includes access to online version with complete text, images and video

Presents evidence-based spine trauma management in a concise, user-friendly format Representing the collective efforts of a multinational, multidisciplinary panel of spine and spinal cord trauma masters, this beautifully illustrated evidence-based textbook does more than provide multiple treatment options -- it offers unique access to insights from recognized spine experts and a thoughtful yet practical review of the most relevant literature and clinical evidence available in the field today. Each chapter centers on pertinent questions and objective reviews of state-of-the-art procedures that guide readers from an evaluation of the evidence through practical recommendations they can easily apply to their own practices. Features: Succinct outline format -- easy to read and reference 138 detailed evidentiary tables appear throughout the text An innovative new classification system for spine trauma developed by The Spine Trauma Study Group, composed of 50 internationally recognized spine experts High-quality radiographs and full-color drawings and photographs complement the text Practical recommendations for the treatment of many common spinal injuries, including odontoid fractures, central cord injuries, and thoraco-lumbar flexion distraction injuries --in-depth information on everything from intensive care to rehabilitation An accompanying DVD contains 15 narrated videos -- over one hour of footage -- of actual procedures by the authors Spine and Spinal Cord Trauma: Evidence-Based Management is an invaluable reference for orthopaedic surgeons, neurosurgeons, residents and fellows in those specialties, and allied health professionals who care for spine injury patients.

In this issue of Radiologic Clinics, guest editor Dr. Vinil Shah brings his considerable expertise to the topic of Spine Imaging. Top experts in the field cover essentials of spinal tumor ablation; spinal CSF leak localization with dynamic CT myelography; endovascular treatment of CSF venous fistulas; imaging of discogenic and vertebrogenic pain; and more. - Contains 14 relevant, practice-oriented topics including functional anatomy of the spinal cord; diffusion tensor imaging of the spinal cord: clinical applications; 3-D printing in treatment planning of spinal deformities and tumors; role of high-resolution MR imaging (MR neurography) in diagnosis and treatment of peripheral nerve disorders; practical artificial intelligence applications in spinal imaging; and more. - Provides in-depth clinical reviews on spine imaging, offering actionable insights for clinical practice. - Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.

Using a problem-solving approach based on clinical evidence, Neurological Rehabilitation, 6th Edition covers the therapeutic management of people with functional movement limitations and quality of life issues following a neurological event. It reviews basic theory and covers the latest screening and diagnostic tests, new treatments, and interventions commonly used in today's clinical practice. This edition includes the latest advances in neuroscience, adding new chapters on neuroimaging and clinical tools such as virtual reality, robotics, and gaming. Written by respected clinician and physical therapy expert Darcy Umphred, this classic neurology text provides problem-solving strategies that are key to individualized, effective care. UNIQUE! Emerging topics are covered in detail, including chapters such as Movement Development Across the Lifespan, Health and Wellness: The Beginning of the Paradigm, Documentation, and Cardiopulmonary Interactions. UNIQUE! A section on neurological problems accompanying specific system problems includes hot topics such as poor vision, pelvic floor dysfunction, and pain. A problem-solving approach helps you apply your knowledge to examinations, evaluations, prognoses, and intervention strategies. Evidence-based research sets up best practices, covering topics such as the theory of neurologic rehabilitation, screening and diagnostic tests, treatments and interventions, and the patient's psychosocial concerns Information. Case studies use real-world examples to promote problem-solving skills. Non-traditional approaches to neurological interventions in the Alternative and Complementary Therapies chapter include the movement approach, energy approach, and physical body system approaches therapies. Terminology adheres to the best practices of the APTA as well as other leading physical therapy organizations, following The Guide to Physical Therapy Practice, the Nagi model, and the ICF World Health Model of patient empowerment. Updated illustrations provide current visual references. NEW chapters on imaging and robotics have been added. Updated chapters incorporate the latest advances and the newest information in neuroscience and intervention strategies. Student resources on an Evolve companion website include references with links to MEDLINE and more.

Using a problem-solving approach based on clinical evidence, Neurological Rehabilitation, 6th Edition covers the therapeutic management of people with functional movement limitations and quality of life issues following a neurological event. It reviews basic theory and covers the latest screening and diagnostic tests, new treatments, and interventions commonly used in today's clinical practice. This edition includes the latest advances in neuroscience, adding new chapters on neuroimaging and clinical tools such as virtual reality, robotics, and gaming. Written by respected clinician and physical therapy expert Darcy Umphred, this classic neurology text provides problem-solving strategies that are key to individualized, effective care. UNIQUE! Emerging topics are covered in detail, including chapters such as Movement Development Across the Lifespan, Health and Wellness: The Beginning of the Paradigm, Documentation, and Cardiopulmonary Interactions. UNIQUE! A section on neurological problems accompanying specific system problems includes hot topics such as poor vision, pelvic floor dysfunction, and pain. A problem-solving approach helps you apply your knowledge to examinations, evaluations, prognoses, and intervention strategies. Evidence-based research sets up best practices, covering topics such as the theory of neurologic rehabilitation, screening and diagnostic tests, treatments and interventions, and the patient's psychosocial concerns Information. Case studies use real-world examples to promote problem-solving skills. Non-traditional approaches to neurological interventions in the Alternative and Complementary Therapies chapter include the movement approach, energy approach, and physical body system approaches therapies. Terminology adheres to the best practices of the APTA as well as other leading physical therapy organizations, following The Guide to Physical Therapy Practice, the Nagi model, and the ICF World Health Model of patient empowerment. Updated illustrations provide current visual references. NEW chapters on imaging and robotics have been added. Updated chapters incorporate the latest advances and the newest information in neuroscience and intervention strategies. Student resources on an Evolve companion website include references with links to MEDLINE and more.