This book, the first of three volumes, provides a thorough background to the emerging field of neurobehavioral toxicology by looking at current clinical approaches and tests, as well as assessing current clinical research. The analysis of the impact of toxins on the human nervous system is particularly pertinent given the ongoing expansion of pharmaceuticals, industrial hazards, biological warfare and global pollution. A comprehensive introduction to neurobehavioral toxicology, this work will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.

This is the final volume in a three-volume work that has addressed the scientific methodologies relevant to clinical neurobehavioral toxicology. Volume III attends to what is known about industrial and environmental chemicals, medicines, and substances of abuse and how these agents affect the central nervous system. How to determine that a specified substance has caused harm is emphasized by way of case examples and discussion. Illnesses and behavioral variations that compete with toxicant-induced explanations for findings in a given case, as well as the various controversies that can arise around issues of diagnosis and causal determination, are treated comprehensively in this volume.

This book, the first of three volumes, provides a thorough background to the emerging field of neurobehavioral toxicology by looking at current clinical approaches and tests, as well as assessing current clinical research. The analysis of the impact of toxins on the human nervous system is particularly pertinent given the ongoing expansion of pharmaceuticals, industrial hazards, biological warfare and global pollution. A comprehensive introduction to neurobehavioral toxicology, this work will be of interest to practicing neurologists and neuropsychologists, as well as to occupational medicine physicians and medical toxicologists.

Containing 50 chapters by some of the most prominent clinical neuropsychologists, the Textbook of Clinical Neuropsychology sets a new standard in the field in its scope, breadth, and scholarship. Unlike most other books in neuropsychology, the Textbook is organized primarily around syndromes, disorders, and related clinical phenomena. Written for the clinician at all levels of training, from the beginner to the journeyman, the Textbook presents contemporary clinical neuropsychology in a comprehensive volume. Chapters are rich with reviews of the literature and clinical case material spanning a range from pediatric to adult and geriatric disorders. Chapter authors are among the most respected in their field, leaders of American Neuropsychology, known for their scholarship and professional leadership. Rarely have so many distinguished members of one discipline been in one volume. This is essential reading for students of neuropsychology, and all others preparing for careers in the field.

Explains the treatments used in brain injury rehabilitation and covers new methods of rehabilitation, including complementary medicine theories.

Mild Cognitive Impairment (MCI) has been identified as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD). Since treatments for AD are most likely to be most effective early in the course of the disease, MCI has become a topic of great importance and has been investigated in different populations of interest in many countries. This book brings together these differing perspectives on MCI for the first time. This volume provides a comprehensive resource for clinicians, researchers, and students involved in the study, diagnosis, treatment, and rehabilitation of people with MCI. Clinical investigators initially defined mild cognitive impairment (MCI) as a transitional condition between normal aging and the early stages of Alzheimer’s disease (AD). Because the prevalence of AD increases with age and very large numbers of older adults are affected worldwide, these clinicians saw a pressing need to identify AD as early as possible. It is at this very early stage in the disease course that treatments to slow the progress and control symptoms are likely to be most effective. Since the first introduction of MCI, research interest has grown exponentially, and the utility of the concept has been investigated from a variety of perspectives in different populations of interest (e.g., clinical samples, volunteers, population-based screening) in many different countries. Much variability in findings has resulted. Although it has been acknowledged that the differences observed between samples may be ‘legitimate variations’, there has been no attempt to understand what it is we have learned about MCI (i.e., common features and differences) from each of these perspectives. This book brings together information about MCI in different populations from around the world. Mild Cognitive Impairment will be an important resource for any clinician, researcher, or student involved in the study, detection, treatment, and rehabilitation of people with MCI.

Substance use continues to be a major public health problem, and the ramifications of this are manifold. For instance, at present, on a yearly basis, the total economic cost of substance misuse is literally hundreds of billions of dollars. These costs are related to a number of factors, including, but not limited to, treatment and prevention, reduced job productivity and/or absenteeism, interdiction by the criminal justice, and incarceration. There are many more psychosocial consequences of substance misuse, and these have been well–documented over the past four to five decades; in contrast, with the exception of alcohol, the effects of substance misuse on the brain have received attention only in the past 10 to 15 years. An emerging body of literature has reported on the effects of various drugs on neuropsychological functioning, including benzodiazepines, cocaine, marijuana, MDMA, methamphetamine, nicotine, and opioids. Despite the fact that the neuropsychological consequences of many drugs of abuse are well–documented, to our knowledge, no one had previously published an edited volume that focused exclusively on this issue. Based on this fact, we decided to create a volume that would review the available literature regarding on this topic. Neuropsychology and Substance Misuse: State-of-the-Art and Future Directions explores cutting-edge issues, and will be of interest to clinical neuropsychologists who require the latest findings in this increasingly important area of neuropsychology.

Cognitive reserve has emerged as a powerful concept for interpreting individual differences in susceptibility to, and recovery from, brain injury or pathology. Underlying cognitive reserve is the idea that individual differences in how cognitive tasks are mediated in the brain allow some people to cope with pathology to a greater degree than others. Cognitive Reserve: Theory and Applications describes in depth the source of these individual differences. This volume provides a comprehensive review of theory, research and clinical application of the cognitive reserve. Chapters explore the theoretical underpinnings of cognitive reserve, and evidence for its existence. Various approaches for studying this concept are addressed, including epidemiologic, cognitive experimental, and neuroimaging. Possible genetic and physiologic underpinnings of cognitive reserve are presented. Application of this concept to a wide range of situations, including child development, aging, Alzheimer’s disease, stroke, HIV, and head injury is discussed. The result is an up-to-date, global treatment of cognitive reserve that will be of interest to someone new to the concept or the experienced investigator.

The text provides a lifespan developmental approach to neuropsychology. It addresses the many issues in neuropsychological assessment that differ between younger and older adults. It describes the symptoms, neuropathology, diagnostic considerations, and treatment options of common neurological disorders associated with aging. It also addresses special considerations related to geriatric neuropsychology, such as ethical issues, family systems issues, decision-making capacity, cultural consideration, and medical/medication/substance use issues. Additionally, a list of resources for the elderly and their families is also provided.