This clinically focused book aims to cover for the first time all of the neurological aspects relevant to the diagnosis and treatment of spinal cord disease. Furthermore, innovative neurorestorative therapeutic strategies - aiming for repair of the damaged spinal cord and/or reorganization of the remaining nervous system - with significant potential for translation into clinical routine are presented. The book covers a comprehensive list of topics, including epidemiology, neuroanatomy, etiology of compressive and non-compressive spinal cord injury, imaging, neurophysiology, neurological sequelae, and complications with emphasis on dysfunction of the autonomic nervous system. Both clinically established and preclinical therapies are discussed in detail. The book is suited for trainees and practicing clinicians including neurologists, spine surgeons, rehabilitation specialists, neuroradiologists, and occupational/physical therapists; it will also be of value to neuroscientists involved in research into spinal cord disease.

This book provides a comprehensive overview of the current state of the art of practical applications of neuroprosthesis based on functional electrical stimulation for restoration of motor functions lost by spinal cord injury and discusses the use of brain-computer interfaces for their control. The book covers numerous topics starting with basics about spinal cord injury, electrical stimulation, electrical brain signals and brain-computer interfaces. It continues with an overview of neuroprosthetic solutions for different purposes and non-invasive and invasive brain-computer interface implementations and presents clinical use cases and practical applications of BCIs. Finally, the authors give an outlook on cutting edge research with a high potential for clinical translation in the near future. All authors committed themselves to use easy-to-understand language and to avoid very specific information, focusing instead on the essential aspects. This makes this book an ideal choice not only for researchers and clinicians at all stages of their education interested in the topic of brain-computer interface-controlled neuroprostheses, but also for end users and their caregivers who want to inform themselves about the current technological possibilities to improve paralyzed motor functions.

Diagnosis and Treatment of Spinal Cord Injury will enhance readers' understanding of the complexities of the diagnosis and management of spinal cord injuries. Featuring chapters on drug delivery, exercise, and rehabilitation, this volume discusses in detail the impact of the clinical features, diagnosis, management, and long-term prognosis of spinal cord injuries on the lives of those affected. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand spinal cord injuries. Spinal injury affects about 10 million people annually worldwide, impacting on the family unit and causing lifelong disabilities, with varied symptoms including paresthesia, spasticity, loss of motor control, and often severe pain. Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury will enhance readers' understanding of the biological and psychological effects of spinal cord injury. Featuring chapters on gene expression, metabolic effects, and behavior, this volume discusses in detail the impact of spinal cord injury to better understand the underlying pathways and processes. The book has applicability for neuroscientists, neurologists, clinicians, and anyone working to better understand these injuries. Diagnosis and Treatment of Spinal Cord Injury: - Covers both the diagnosis and treatment of spinal cord injury - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on epidemiology and pain - Includes MRI usage, biomarkers, and stem cell and gene therapy for management of spinal cord injury - Discusses pain reduction, drug delivery, and rehabilitation Cellular, Molecular, Physiological, and Behavioral Aspects of Spinal Cord Injury: - Summarizes the neuroscience of spinal cord injury, including cellular and molecular biology - Contains chapter abstracts, key facts, dictionary, and summary points to aid in understanding - Features chapters on signaling and hormonal events - Includes plasticity and gene expression - Examines health and stress behaviors after spinal cord injury

The 2nd Edition of this comprehensive text features practical guidance on how to diagnose and manage the neurological effects and complications of every major category of recreationally used drugs. Book jacket.

This revised, updated, and substantially expanded third edition provides an accessible, practical overview of major areas of research, technical development and clinical application in the field of neurorehabilitation movement therapy. The initial section provides the basic framework and a rationale for technology application in movement therapy by summarizing recent findings in neuroplasticity and motor learning. The following section provides a detailed overview of the movement physiology of various neurologic conditions, illustrating how this knowledge has been used to design various neurorehabilitation technologies. The third section then explains the principles of human-machine interaction for movement rehabilitation. The fourth section provides an overview of assessment technology and predictive modeling in neurorehabilitation. The fifth section provides a survey of technological approaches to neurorehabilitation, including spinal cord stimulation, functional electrical stimulation, virtual reality, wearable sensing, brain computer interfaces, mobile technologies, and telerehabilitation. The final two sections examine in greater detail the ongoing revolution in robotic therapy for upper extremity movement and walking, respectively. The promises and limitations of these technologies in neurorehabilitation are discussed, including an Epilogue which debates the impact and utility of robotics for neurorehabilitation. Throughout the book the chapters provide detailed practical information on state-of-the-art clinical applications of these devices following stroke, spinal cord injury, and other neurologic disorders and future developments in the field. The text is illustrated throughout with photographs and schematic diagrams which serve to clarify the information for the reader. Neurorehabilitation Technology, Third Edition is a valuable resource for neurologists, biomedical engineers, roboticists, rehabilitation specialists, physiotherapists, occupational therapists and those training in these fields. Chapter “Spinal Cord Stimulation to Enable Leg Motor Control and Walking in People with Spinal Cord Injury is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

...a classic monograph that serves as a diagnostic guide to neurologic levels for residents in both orthopedics and neurology.