Featuring 127 new drug entries, the eighth edition of this popular reference provides practical, reliable information on more than 1,175 drugs that may be used by pregnant and lactating women.

This fourth edition of Current Cardiovascular Drugs is designed to provide an updated practical compendium of current knowledge regarding cardiovascular drug therapy in a concise, easily readable format. The book is organized into chapters by drug class, and details the pharmacologic characteristics of specific treatment entities. The clinical efficacy and limitations of the various drug therapies are discussed using supportive reference material from the most authoritative sources and published clinical trials. The book is for practicing physicians, physician's assistants, pharmacists, nurse practitioners, nurses, and residents.

A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting. These leading basic and fundamental authorities survey such important new drugs as calcium-influx inhibitors, free-radical scavenging drugs, glutamate and glycinergic antagonists, and immune suppressors. They also evaluate all the latest findings concerning calcium homeostasis, glutamate toxicity, gene activation, and the role of free radicals, glycine, and hormones. Chapters devoted to the neuroimaging of stroke, clinical trials, and the role of cerebral immune activation complete this informative collection of cutting-edge reviews.

This textbook aims to examine some of the most controversial areas of neurological surgery by applying the current evidence to illuminate our understanding of the pathophysiology of each disease and the outcomes from surgical and non-surgical treatments. The Evidence for Neurosurgery is a textbook that will challenge current dogmas in many instances, provide an organized framework for understanding where current evidence can be applied clinically, and illustrate where gaps in the evidence exist and how these deficiencies may be filled in the future. In the first chapter, "Clinical Evidence", the reader will gain an understanding of the levels of clinical evidence and will learn what types of study designs are appropriate and in which situations. The textbook is then divided into six sections: Spine, Vascular, Tumor, Pediatrics, Functional, and Trauma.

More than 40 articles provide an extensive coverage of clinical and basic science advances over the last three years of research on subarachnoid hemorrhage-induced brain injuries. Early brain injury, the new frontier of subarachnoid research, which may be a key contributor to the high mortality and morbidity, promotes collaborative efforts from neurosurgery, neurology, neuro-ICU into other interrelated fields and basic neurosciences. For the first time, subarachnoid hermorrhage research is almost equally divided by early brain injury and cerebral vasospasm, mechanistic investigations and therapeutic approaches, demonstrating a translational feature of the future direction.

The Second Edition of this handy review is formatted for ease of use. Over 300 detailed entries include key points, a discussion, and suggested readings for each keyword. Broad-based coverage addresses all areas of anesthesiology, including pediatrics. New key words have been added to this edition, and questions and answers at the end of each keyword presentation test and reinforce readers’ knowledge. A companion website includes fully searchable text.

Basic research, progress in technology and informatics, and the success of clinical pharmacology are the fundamental bases of this interesting field of medicine. Nowadays, critical care medicine is no longer for experts only, but it is a field in which researchers and clinicians, nurses and technical staff work in an interdisciplinary way, each offering their own skills. The volume is divided in six sections, devoted to critical care key issues, to lung diseases, to trauma, to acid-base equilibrium, to perioperative medicine, and to obstetrics.

Part of the Drugs in series, this book provides an easily accessible pocket-sized guide to the use of medications when treating patients with neurological ailments. Drugs in Neurology covers the breadth of medications used in modern neurology, including each drug's indications, contra-indications, side-effects and important interactions. The underlying pharmacology also feature (where known). Practical aspects related to prescribing and therapeutic drug monitoring are covered and based on the most up-to-date evidence-based guidance. Each drug monograph contains a small section drawing on the wisdom of the senior contributors of each chapter with regards to using the medication.

This volume sets a basis for effective translational research. Authored by experts in the field of translational stroke research, each chapter specifically addresses one or more components of preclinical stroke research. The emphasis is placed on target identification and drug development using state-of-the-art in vitro and in vivo assays, in combination with in vitro toxicology assays, AMDE and clinical design.