Sometimes in life things are bound to get noisy, and if that's the case, why not learn from them? With the help of this informative book, readers perform exciting experiments and learn why and how certain items make certain sounds. Accessible step-by-step instructions correlate closely with eye-popping illustrations, ensuring readers of many ages and levels can follow along with these amazing activities. Each exciting project encourages readers to use their critical thinking skills and draw conclusions based on the experiments they perform.

Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.

Praise for the First Edition: "If you ... want an up-to-date, definitive reference written by authors who have contributed much to this field, then this book is an essential addition to your library." —Journal of the American Statistical Association A COMPREHENSIVE REVIEW OF MODERN EXPERIMENTAL DESIGN Experiments: Planning, Analysis, and Optimization, Third Edition provides a complete discussion of modern experimental design for product and process improvement—the design and analysis of experiments and their applications for system optimization, robustness, and treatment comparison. While maintaining the same easy-to-follow style as the previous editions, this book continues to present an integrated system of experimental design and analysis that can be applied across various fields of research including engineering, medicine, and the physical sciences. New chapters provide modern updates on practical optimal design and computer experiments, an explanation of computer simulations as an alternative to physical experiments. Each chapter begins with a real-world example of an experiment followed by the methods required to design that type of experiment. The chapters conclude with an application of the methods to the experiment, bridging the gap between theory and practice. The authors modernize accepted methodologies while refining many cutting-edge topics including robust parameter design, analysis of non-normal data, analysis of experiments with complex aliasing, multilevel designs, minimum aberration designs, and orthogonal arrays. The third edition includes: Information on the design and analysis of computer experiments A discussion of practical optimal design of experiments An introduction to conditional main effect (CME) analysis and definitive screening designs (DSDs) New exercise problems This book includes valuable exercises and problems, allowing the reader to gauge their progress and retention of the book's subject matter as they complete each chapter. Drawing on examples from their combined years of working with industrial clients, the authors present many cutting-edge topics in a single, easily accessible source. Extensive case studies, including goals, data, and experimental designs, are also included, and the book's data sets can be found on a related FTP site, along with additional supplemental material. Chapter summaries provide a succinct outline of discussed methods, and extensive appendices direct readers to resources for further study. Experiments: Planning, Analysis, and Optimization, Third Edition is an excellent book for design of experiments courses at the upper-undergraduate and graduate levels. It is also a valuable resource for practicing engineers and statisticians.

This user-friendly new edition reflects a modern and accessible approach to experimental design and analysis Design and Analysis of Experiments, Volume 1, Second Edition provides a general introduction to the philosophy, theory, and practice of designing scientific comparative experiments and also details the intricacies that are often encountered throughout the design and analysis processes. With the addition of extensive numerical examples and expanded treatment of key concepts, this book further addresses the needs of practitioners and successfully provides a solid understanding of the relationship between the quality of experimental design and the validity of conclusions. This Second Edition continues to provide the theoretical basis of the principles of experimental design in conjunction with the statistical framework within which to apply the fundamental concepts. The difference between experimental studies and observational studies is addressed, along with a discussion of the various components of experimental design: the error-control design, the treatment design, and the observation design. A series of error-control designs are presented based on fundamental design principles, such as randomization, local control (blocking), the Latin square principle, the split-unit principle, and the notion of factorial treatment structure. This book also emphasizes the practical aspects of designing and analyzing experiments and features: Increased coverage of the practical aspects of designing and analyzing experiments, complete with the steps needed to plan and construct an experiment A case study that explores the various types of interaction between both treatment and blocking factors, and numerical and graphical techniques are provided to analyze and interpret these interactions Discussion of the important distinctions between two types of blocking factors and their role in the process of drawing statistical inferences from an experiment A new chapter devoted entirely to repeated measures, highlighting its relationship to split-plot and split-block designs Numerical examples using SAS® to illustrate the analyses of data from various designs and to construct factorial designs that relate the results to the theoretical derivations Design and Analysis of Experiments, Volume 1, Second Edition is an ideal textbook for first-year graduate courses in experimental design and also serves as a practical, hands-on reference for statisticians and researchers across a wide array of subject areas, including biological sciences, engineering, medicine, pharmacology, psychology, and business.

The study of phase transitions is among the most fascinating fields in physics. Originally limited to transition phenomena in equilibrium systems, this field has outgrown its classical confines during the last two decades. The behavior of far from equilibrium systems has received more and more attention and has been an extremely active and productive subject of research for physicists, chemists and biologists. Their studies have brought about a more unified vision of the laws which govern self-organization processes of physico-chemical and biological sys tems. A major achievement has been the extension of the notion of phase transi tion to instabilities which occur only in open nonlinear systems. The notion of phase transition has been proven fruitful in apphcation to nonequilibrium ins- bihties known for about eight decades, like certain hydrodynamic instabilities, as well as in the case of the more recently discovered instabilities in quantum optical systems such as the laser, in chemical systems such as the Belousov-Zhabotinskii reaction and in biological systems. Even outside the realm of natural sciences, this notion is now used in economics and sociology. In this monograph we show that the notion of phase transition can be extend ed even further. It apphes also to a new class of transition phenomena which occur only in nonequilibrium systems subjected to a randomly fluctuating en vironment.

Primarily intended for the undergraduate and postgraduate students of psychology, this book will help understand the methodology of experiments and the basic concepts of experimental psychology. Since the experiments are described in detail with the help of purely hypothetical data, the readers will easily understand the procedure and the steps involved in each experiment. Complete reports of more than fifty experiments will certainly help understand the significance of each step in an experiment. The detailed description of experiments will also help in conceptualising relevant problems and designing appropriate experiments. Another feature is that, more than half of the experiments described in the book do not require sophisticated apparatus. Key Features • Sample data are provided in each experiment. • Theoretical background of experiments is sufficient and clear. • Sample data are analysed with the help of statistical techniques. • Language is lucid and easy to comprehend. • Experiments on most of the topics have been covered.

A thorough reference work bridging the gap between contemporary and traditional approaches to noise problems Noise in semiconductor devices refers to any unwanted signal or disturbance in the device that degrades performance. In semiconductor devices, noise is attributed to hot-electron effects. Current advances in information technology have led to the development of ultrafast devices that are required to provide low-noise, high-speed performance. Microwave Noise in Semiconductor Devices considers available data on the speed versus noise trade-off and discusses optimal solutions in semiconductors and semiconductor structures. These solutions are of direct interest in the research and development for fast, efficient, and reliable communications systems. As the only book of its kind accessible to practicing engineers, the material is divided into four parts-the kinetic theory of fluctuations and its corollaries, the methods of measurements of microwave noise, low-dimensional structures, and, finally, devices. With over 100 illustrations presenting recent experimental data for up-to-date semiconductor structures designed for ultrafast electronics, together with results of microscopic simulation where available, these examples, tables, and references offer a full comprehension of electronic processes and fluctuation in dimensionally quantizing structures. Bridging the apparent gap between the microscopic approach and the equivalent circuit approach, Microwave Noise in Semiconductor Devices considers microwave fluctuation phenomena and noise in terms of ultrafast kinetic processes specific to modern quantum-well structures. Scientists in materials science, semiconductor and solid-state physics, electronic engineers, and graduate students will all appreciate this indispensable review of contemporary and future microwave and high-speed electronics.

This open-access book empowers its readers to explore the acoustic world of animals. By listening to the sounds of nature, we can study animal behavior, distribution, and demographics; their habitat characteristics and needs; and the effects of noise. Sound recording is an efficient and affordable tool, independent of daylight and weather; and recorders may be left in place for many months at a time, continuously collecting data on animals and their environment. This book builds the skills and knowledge necessary to collect and interpret acoustic data from terrestrial and marine environments. Beginning with a history of sound recording, the chapters provide an overview of off-the-shelf recording equipment and analysis tools (including automated signal detectors and statistical methods); audiometric methods; acoustic terminology, quantities, and units; sound propagation in air and under water; soundscapes of terrestrial and marine habitats; animal acoustic and vibrational communication; echolocation; and the effects of noise. This book will be useful to students and researchers of animal ecology who wish to add acoustics to their toolbox, as well as to environmental managers in industry and government.