Novel Treatments of Strong Correlations, Volume 90 in the Advances in Quantum Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Topics covered include Coupled Cluster, Stochastic CC, NOFT, Breaking the Symmetry Dilemma : Capturing Strong-Correlations by Restoration of Broken Symmetry Solutions, Flexible wavefunctions, Electronic Coupling to Optical Cavity Modes, Multireference Perturbation Theories Based on the Dyall Hamiltonian, The GW Approximation: A Quantum Chemistry Perspective, Geminals, and more. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in Advances in Quantum Chemistry series - Updated release includes the latest information on this timely topic

​This book presents up-to-date information on clinical and research applications of imaging in peripheral arterial disease (PAD). It provides high-quality images useful not only in the diagnosis of PAD but also for use in clinical trials aimed at the development of novel therapies such as angiogenic agents and stem cells. The book begins with coverage of the applications of the four major imaging modalities in a clinical setting: ultrasound, computed tomography angiography (CTA), magnetic resonance angiography (MRA), and digital subtraction angiography (DSA). It also discusses the ankle brachial index (ABI) as a screening technique to establish the presence of PAD. Subsequent chapters focus on the advantages and limitations of various research applications of imaging in PAD including contrast ultrasound for measuring perfusion; MRI for assessing perfusion, energetics, plaque volume, and characteristics; and radionuclide imaging for perfusion and inflammation. Imaging in Peripheral Arterial Disease: Clinical and Research Applications is an essential resource for physicians, researchers, residents, and fellows in cardiology, radiology, imaging, nuclear medicine, diagnostic radiology, and vascular surgery.

The 7th volume of the book series Acute Leukemias provides new updates on the biology of acute leukemias and especially the underlying genetic and molecular events. High quality contributions are provided by leading scientists and clinicians making the book an excellent overview over most recent achievements which translate into new treatment strategies and hence an improved outlook for patients suffering from acute leukemias.

Acute Leukemias IX provides an extended and thorough overview of recent developments in cell biology and experimental therapy for acute leukemias. Following the tradition of the Acute Leukemias series since 1987, this book bridges the gap between basic research and clinical studies and emphasizes that both aspects are equally necessary to achieve improvements, not only in understanding the disease but also in providing better therapy. As a forum for world-wide activities in the field of acute leukemias the volume contains invaluable contributions that provide the reader with new, previously unpublished information.

This book provides a practical guide to decision making in head and neck oncologic surgery. As new technology is introduced, there is increasing knowledge regarding the efficacy of traditional head and neck surgical therapies and how to select among these varied and complex approaches is becoming increasingly difficult. Concise easy to follow chapters are devoted to one or two specific questions or decisions in head and neck oncologic surgery, aiding the reader to develop their decision making skills. Difficult Decisions in Head and Neck Oncologic Surgery is a timely reference source for practicing surgeons, surgeons in training, and educators on the recommended ideal approaches in selected clinical situations.

Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in clinical development, this book discusses various potential drug development strategies, the design and analysis of pharmacokinetics (PK) studies, and the design and analysis of efficacy studies.