Historically, nutrient deficiencies have been of greater concern than dietary excess. However, along with the realization that deaths due to certain diseases are more prevalent in affluent countries came the conclusion that nutritional excess is of equal or in greater concern in many nations. Because immunologic reactions may play a role development of both cancer and atherosclerosis, better understanding of these interre lated phenomena may lead to innovative ideas for control of these diseases. There has been considerable interest in the role various nutrients may play in regulating immunologic responses. This has been especially true as a possible mecha nism by which fat modulates growth of tumors in animals. Likewise, deficiency or excess of a number of other individual nutrients have been linked to altered immune responses. This volume of Human Nutrition-A Comprehensive Treatise details the effects of a number of nutrients on immunity. The first chapter covers questionable and fraudu lent claims linking nutrition and immunity. The next chapter examines several aspects of food allergy. Ensuing chapters focus on specific nutrients such as fat, cholesterol, arginine, vitamins C, A, and E, carotenoids, flavonoids, zinc, iron, copper, and sele nium. There are two chapters on total energy intake affecting immune response, one examining protein-energy malnutrition and the other describing the effects of food restriction in otherwise healthy animals.

It is a pleasure to write the foreword to Nutrition and Table 1 Nutritional Status and Outcome of Infection Immunology: Principles and Practice. In fact, this book comes at a timely moment, when the impact of nutrition and Definite adverse outcome immunology is being widely felt because of the AIDS epi Measles, diarrhea, tuberculosis demic. This is particularly of note in Africa, where large Probable adverse outcome HIV, malaria, pneumonia sums of money are being spent on nutritional intervention Little or no effect programs in the hopes of improving immune responsive Poliomyelitis, tetanus, viral encephalitis ness. We should not forget, however, early advances in our Note: HIV= human immunodeficiency virus understanding of protein energy malnutrition (PEM). PEM can be used as a model to understand the nutritional basis of immunity, as well as the immunological influences on nutri tional status. Despite advances in agricultural production, tance. However, both in vitro studies and tests in laboratory PEM continues to affect hundreds of millions ofthe world's animals may have little resemblance to what is experienced population. The functional impact of undernutrition varies in humans under field conditions. from mild morbidity to life-threatening infection.

This text provides a review of the roles of specific nutrients in maintaining the immune response and host protection against infection. It also considers the influence of various factors, such as exercise and ageing, on the interaction between nutrition and immune function.

This volume provides an authoritative and balanced account of current knowledge and practice in the area of clinical nutrition.

The rapidity of scientific progress over the last few years guarantees the utility of this new collection of state-of-the-art reviews on the immunology of aging, which is the result of extensive collaboration of more than sixty of the greatest thinkers and scholars in the field, in cooperation with a number of junior colleagues. The book summarizes current knowledge on the cellular and molecular aspects of the aging immune system and their clinical relevance, providing insights into the effects of the aging process on susceptibilities to those diseases most common among elders. The retrieval strategies used to slow down the decline in the immune system in the elderly are another subject detailed extensively. By providing a broad overview of immunosenescence and its consequences, as well as their potential modulation, this book will fill a gap in a timely manner. It will be of value to all immunologists, whether novice or experienced, as well as geriatricians and epidemiologists.

The field of geriatric rehabilitation is constantly changing due to the discovery of new evidence-based evaluation and treatment strategies, as well as the continual support or refutation of older theories and practices. Now in itsFourth Edition, A Clinical Approach to Geriatric Rehabilitation has been updated to be at the forefront of these changes and includes free video content from MedBridge and a discount on a MedBridge subscription to geriatric rehabilitation courses offered by the authors. Drs. Jennifer M. Bottomley and Carole B. Lewis have compiled the plethora of available scientific research on geriatric populations and combined it with their years of actual clinical practice. Together this makes this text a complete evidence-based guide to the clinical care of geriatric patients and clients. The first part of A Clinical Approach to Geriatric Rehabilitation, Fourth Edition tackles applied gerontological concepts, providing the general knowledge base necessary for treating geriatric patients. Topics in this section include patient evaluation, an exploration of nutritional needs, and age-related changes in physiology and function, as well as many other foundational areas. In the second section, topics become more focused on patient care concepts like neurologic considerations, cardiopulmonary and cardiovascular considerations, and establishing community-based screening programs. In the final section, chapters center on administration and management, including important subjects such as attitudes, ethics, and legal topics, as well as consultation and research. New and updated in the Fourth Edition: Pearls section for succinct highlights of the content within each chapter The latest evidence-based practice interventions with complete references for further reading Updated graphics, pictures, and diagrams to illustrate the content Content summaries and streamlined text for enhanced readability Updated case studies to exemplify clinical decision-making Designed to provide valuable, real-life clinical knowledge, A Clinical Approach to Geriatric Rehabilitation, Fourth Edition gives physical therapists an evidence-based guide to the clinical aspects of rehabilitative care in older adult patients and clients.